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OPENSEQ.org
LIPB - Octanoyltransferase
UniProt: P60720 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11591
Length: 213 (202)
Sequences: 1384
Seq/Len: 6.85
LIPB
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
109_V 137_C 3.976 1.00
85_M 152_L 3.762 1.00
107_Q 111_N 3.067 1.00
115_E 198_N 2.828 1.00
14_Q 41_V 2.772 1.00
138_S 176_M 2.647 1.00
118_I 179_I 2.561 1.00
110_V 122_P 2.411 1.00
10_Q 192_A 2.333 1.00
14_Q 19_I 2.297 1.00
30_R 36_D 2.198 1.00
40_L 85_M 2.193 1.00
112_T 198_N 2.174 1.00
158_M 178_K 2.096 1.00
108_T 199_I 2.082 1.00
116_L 194_R 2.082 1.00
111_N 201_A 2.034 1.00
17_E 21_Q 2.018 1.00
101_L 141_L 2.002 1.00
107_Q 122_P 1.876 1.00
118_I 131_V 1.851 1.00
115_E 194_R 1.845 1.00
87_V 105_L 1.821 1.00
113_L 136_I 1.818 1.00
58_I 75_V 1.763 1.00
25_E 29_T 1.761 1.00
154_L 191_I 1.745 1.00
13_L 44_Y 1.657 1.00
83_Q 195_L 1.603 1.00
13_L 42_E 1.598 1.00
57_H 74_Q 1.591 1.00
134_K 175_E 1.583 1.00
21_Q 24_H 1.554 0.99
152_L 195_L 1.525 0.99
138_S 174_M 1.491 0.99
111_N 202_L 1.486 0.99
115_E 197_E 1.484 0.99
15_P 18_P 1.47 0.99
20_S 70_D 1.46 0.99
98_V 102_V 1.46 0.99
157_N 180_S 1.447 0.99
20_S 24_H 1.433 0.99
178_K 181_Q 1.433 0.99
111_N 198_N 1.409 0.99
15_P 44_Y 1.397 0.99
24_H 70_D 1.375 0.98
11_L 39_W 1.372 0.98
62_G 165_R 1.359 0.98
55_A 68_Q 1.356 0.98
47_F 165_R 1.345 0.98
113_L 120_A 1.344 0.98
98_V 143_I 1.334 0.98
106_E 110_V 1.332 0.98
27_T 149_F 1.328 0.98
19_I 44_Y 1.328 0.98
77_Y 162_P 1.326 0.98
97_G 103_T 1.302 0.98
26_F 34_T 1.254 0.97
187_T 190_N 1.247 0.97
77_Y 158_M 1.236 0.96
100_E 104_L 1.211 0.96
144_R 149_F 1.21 0.96
64_I 162_P 1.21 0.96
112_T 191_I 1.208 0.96
30_R 34_T 1.199 0.96
34_T 37_E 1.19 0.95
158_M 162_P 1.189 0.95
190_N 194_R 1.189 0.95
21_Q 25_E 1.187 0.95
45_P 77_Y 1.186 0.95
180_S 185_E 1.182 0.95
92_K 96_L 1.18 0.95
184_P 190_N 1.177 0.95
19_I 41_V 1.17 0.95
87_V 101_L 1.167 0.95
51_Q 142_R 1.156 0.94
179_I 191_I 1.137 0.94
114_A 119_E 1.132 0.93
85_M 195_L 1.126 0.93
109_V 195_L 1.116 0.93
23_M 39_W 1.114 0.93
85_M 109_V 1.109 0.92
188_T 192_A 1.109 0.92
9_R 39_W 1.108 0.92
199_I 203_L 1.082 0.91
187_T 193_P 1.075 0.91
104_L 203_L 1.075 0.91
91_L 148_S 1.071 0.91
113_L 179_I 1.071 0.91
20_S 69_S 1.068 0.91
99_R 103_T 1.066 0.90
167_N 171_Y 1.058 0.90
15_P 65_P 1.055 0.90
30_R 33_S 1.053 0.90
136_I 177_A 1.052 0.90
177_A 181_Q 1.05 0.89
112_T 194_R 1.045 0.89
168_P 176_M 1.041 0.89
66_V 165_R 1.04 0.89
143_I 148_S 1.04 0.89
112_T 116_L 1.04 0.89
156_V 188_T 1.039 0.89
101_L 148_S 1.036 0.89
96_L 146_G 1.035 0.89
18_P 21_Q 1.028 0.88
161_S 164_L 1.027 0.88
97_G 146_G 1.01 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1w66A10.99061000.358Contact Map0.711
2qhsA10.98591000.384Contact Map0.706
2c8mA40.96711000.495Contact Map0.583
2p0lA111000.501Contact Map0.439
3a7rA10.94841000.526Contact Map0.455
2p5iA10.99061000.539Contact Map0.455
2e5aA10.96711000.548Contact Map0.4
1vqzA10.97651000.62Contact Map0.472
2dxuA20.812294.40.924Contact Map0.737
1biaA10.939930.928Contact Map0.658
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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