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OPENSEQ.org

YRAN - UPF0102 protein YraN
UniProt: P45465 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12779
Length: 131 (115)
Sequences: 1530
Seq/Len: 13.30

YRAN
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
66_R 79_S 4.02 1.00
23_W 67_Y 3.268 1.00
80_V 112_V 3.17 1.00
38_F 54_M 3.035 1.00
62_F 92_A 2.465 1.00
25_A 41_A 2.428 1.00
28_R 38_F 2.393 1.00
28_R 41_A 2.372 1.00
92_A 110_F 2.158 1.00
56_E 124_K 2.129 1.00
61_I 109_R 2.083 1.00
19_T 67_Y 2.059 1.00
28_R 52_L 2.001 1.00
110_F 127_F 1.932 1.00
77_A 114_A 1.875 1.00
76_A 114_A 1.835 1.00
75_G 78_A 1.723 1.00
68_R 79_S 1.71 1.00
27_A 113_V 1.703 1.00
36_L 122_W 1.677 1.00
112_V 126_A 1.672 1.00
113_V 122_W 1.641 1.00
54_M 63_V 1.578 1.00
85_Q 126_A 1.52 1.00
50_I 53_I 1.467 1.00
43_V 94_L 1.442 1.00
28_R 32_E 1.379 0.99
17_K 21_D 1.377 0.99
36_L 54_M 1.364 0.99
42_N 49_E 1.362 0.99
125_D 128_N 1.337 0.99
61_I 122_W 1.306 0.99
48_G 87_K 1.289 0.99
123_I 126_A 1.269 0.99
55_R 58_R 1.257 0.99
56_E 61_I 1.256 0.99
30_W 34_K 1.249 0.99
40_A 99_H 1.242 0.98
28_R 54_M 1.213 0.98
80_V 114_A 1.21 0.98
62_F 108_C 1.196 0.98
81_T 84_K 1.181 0.98
40_A 95_W 1.179 0.98
80_V 84_K 1.168 0.97
76_A 116_T 1.161 0.97
110_F 126_A 1.159 0.97
45_E 91_T 1.155 0.97
34_K 124_K 1.147 0.97
38_F 41_A 1.146 0.97
23_W 115_F 1.126 0.97
96_L 108_C 1.114 0.96
30_W 120_V 1.092 0.96
85_Q 127_F 1.091 0.96
29_R 32_E 1.091 0.96
88_L 127_F 1.074 0.95
43_V 95_W 1.059 0.95
26_Q 115_F 1.059 0.95
77_A 123_I 1.058 0.95
70_S 74_G 1.044 0.94
34_K 122_W 1.036 0.94
60_T 95_W 1.015 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3fovA10.96951000.155Contact Map0.61
1gefA40.801599.90.413Contact Map0.35
1hh1A10.832199.90.421Contact Map0.326
2eo0A20.847399.90.437Contact Map0.525
1ob8A20.85599.90.446Contact Map0.427
2wcwA40.847399.90.496Contact Map0.459
2ostA40.786399.50.651Contact Map0.434
1y88A10.9695990.726Contact Map0.421
3dnxA10.862683.30.892Contact Map0.522
2vldA20.900878.90.897Contact Map0.569

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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