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OPENSEQ.org

YHHQ - Inner membrane protein YhhQ
UniProt: P37619 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12217
Length: 221 (206)
Sequences: 720
Seq/Len: 3.50

YHHQ
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
117_M 161_I 2.854 1.00
125_L 153_S 2.15 1.00
140_W 199_G 2.039 1.00
59_T 71_I 1.987 1.00
157_A 161_I 1.946 1.00
138_R 141_L 1.882 1.00
122_G 150_G 1.752 0.99
75_V 119_Y 1.745 0.99
110_R 163_F 1.743 0.99
152_V 183_Y 1.694 0.99
121_L 153_S 1.673 0.99
73_F 124_I 1.669 0.99
49_F 122_G 1.666 0.99
152_V 156_L 1.657 0.99
25_T 82_I 1.647 0.98
132_R 135_Q 1.647 0.98
128_H 132_R 1.627 0.98
101_L 104_F 1.599 0.98
129_V 133_L 1.571 0.98
57_D 146_S 1.569 0.98
17_S 71_I 1.567 0.98
98_F 102_A 1.551 0.98
195_L 199_G 1.473 0.96
175_W 179_A 1.443 0.96
139_W 143_P 1.442 0.96
31_V 43_T 1.439 0.96
20_H 147_T 1.417 0.95
117_M 157_A 1.416 0.95
123_Q 130_F 1.4 0.95
46_A 182_D 1.396 0.95
144_T 195_L 1.387 0.94
111_I 115_S 1.383 0.94
121_L 157_A 1.374 0.94
155_T 186_K 1.368 0.94
61_R 142_A 1.367 0.94
125_L 129_V 1.365 0.94
126_D 130_F 1.358 0.94
125_L 149_F 1.355 0.93
119_Y 185_F 1.348 0.93
117_M 121_L 1.336 0.93
158_F 162_A 1.323 0.92
56_T 126_D 1.278 0.91
147_T 190_S 1.268 0.90
113_T 138_R 1.263 0.90
114_A 161_I 1.262 0.90
77_I 88_S 1.255 0.89
20_H 199_G 1.251 0.89
43_T 182_D 1.249 0.89
118_A 157_A 1.245 0.89
6_Q 9_R 1.23 0.88
148_L 190_S 1.227 0.88
123_Q 127_V 1.213 0.87
60_V 131_N 1.212 0.87
43_T 159_F 1.209 0.87
137_R 188_L 1.198 0.86
37_I 177_E 1.192 0.86
180_L 184_C 1.174 0.85
125_L 161_I 1.169 0.84
54_L 198_Y 1.169 0.84
188_L 192_V 1.165 0.84
23_V 52_I 1.158 0.84
117_M 180_L 1.144 0.83
100_A 103_H 1.141 0.82
152_V 179_A 1.141 0.82
127_V 130_F 1.14 0.82
35_V 90_F 1.139 0.82
203_N 207_K 1.132 0.82
9_R 210_A 1.132 0.82
49_F 53_F 1.13 0.82
156_L 179_A 1.127 0.81
144_T 150_G 1.111 0.80
126_D 150_G 1.104 0.79
169_A 174_H 1.104 0.79
43_T 178_I 1.104 0.79
42_T 181_V 1.094 0.79
76_M 120_A 1.092 0.78
141_L 164_W 1.089 0.78
34_P 163_F 1.087 0.78
143_P 195_L 1.077 0.77
84_Y 149_F 1.076 0.77
47_F 102_A 1.064 0.76
56_T 190_S 1.057 0.75
65_A 127_V 1.057 0.75
100_A 106_L 1.054 0.75
31_V 182_D 1.051 0.75
140_W 195_L 1.049 0.74
132_R 137_R 1.049 0.74
20_H 75_V 1.04 0.73
122_G 143_P 1.038 0.73
159_F 182_D 1.037 0.73
144_T 147_T 1.035 0.73
54_L 115_S 1.033 0.73
146_S 190_S 1.03 0.72
12_A 62_I 1.029 0.72
148_L 183_Y 1.026 0.72
28_N 115_S 1.025 0.72
110_R 165_R 1.017 0.71
188_L 207_K 1.016 0.71
154_D 186_K 1.016 0.71
26_S 117_M 1.011 0.70
60_V 194_F 1.005 0.70
30_L 44_W 1.003 0.70
49_F 143_P 1.003 0.70
66_P 70_R 1.002 0.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4huqS10.773813.50.958Contact Map0.156
2xq2A10.886910.10.96Contact Map0.14
4dveA30.80097.40.963Contact Map0.225
3p5nA20.77384.80.966Contact Map0.223
3w4tA10.92312.80.969Contact Map0.202
1o22A10.23082.60.97Contact Map0.892
3j1zP20.84621.50.974Contact Map0.201
4humA10.92311.40.974Contact Map0.204
3arcL20.14481.40.974Contact Map0
2kv5A10.12671.30.974Contact Map0.5

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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