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OPENSEQ.org

YBGI - UPF0135 protein YbgI
UniProt: P0AFP6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13305
Length: 247 (246)
Sequences: 1727
Seq/Len: 7.02

YBGI
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
213_A 218_T 3.876 1.00
50_D 85_T 3.297 1.00
169_A 187_V 2.983 1.00
132_E 166_Q 2.657 1.00
37_K 237_D 2.571 1.00
142_L 189_A 2.451 1.00
41_G 62_V 2.45 1.00
192_T 210_F 2.308 1.00
145_W 149_R 2.245 1.00
137_V 145_W 2.211 1.00
19_I 25_N 2.184 1.00
165_V 189_A 2.145 1.00
119_T 134_T 2.128 1.00
86_L 93_L 2.123 1.00
132_E 167_R 2.107 1.00
194_E 212_A 1.996 1.00
6_L 59_A 1.977 1.00
37_K 58_D 1.963 1.00
112_L 150_L 1.936 1.00
138_P 141_E 1.933 1.00
146_I 191_I 1.883 1.00
39_V 57_A 1.875 1.00
36_Q 58_D 1.857 1.00
46_Q 81_N 1.853 1.00
55_L 239_T 1.829 1.00
9_L 229_W 1.829 1.00
227_S 231_N 1.818 1.00
110_A 129_P 1.813 1.00
40_T 227_S 1.801 1.00
49_L 60_V 1.785 1.00
62_V 95_G 1.771 1.00
19_I 102_A 1.761 1.00
49_L 86_L 1.758 1.00
139_G 156_W 1.716 1.00
46_Q 85_T 1.705 1.00
53_V 85_T 1.699 1.00
136_P 164_V 1.694 1.00
37_K 239_T 1.687 1.00
51_E 55_L 1.628 1.00
41_G 60_V 1.601 1.00
139_G 211_Y 1.6 1.00
53_V 89_N 1.565 1.00
193_G 214_G 1.559 1.00
177_S 198_Q 1.555 1.00
50_D 54_R 1.554 1.00
44_A 62_V 1.549 1.00
49_L 85_T 1.545 0.99
86_L 91_I 1.543 0.99
11_N 16_S 1.535 0.99
109_N 172_T 1.53 0.99
67_F 71_E 1.528 0.99
13_K 229_W 1.528 0.99
120_V 132_E 1.496 0.99
3_N 92_N 1.494 0.99
189_A 211_Y 1.478 0.99
192_T 195_V 1.478 0.99
108_N 172_T 1.471 0.99
142_L 168_V 1.469 0.99
171_C 178_F 1.459 0.99
3_N 35_V 1.425 0.99
105_E 110_A 1.424 0.99
46_Q 50_D 1.416 0.99
6_L 35_V 1.414 0.99
139_G 209_H 1.412 0.99
15_N 18_A 1.41 0.99
7_E 11_N 1.388 0.99
37_K 56_G 1.372 0.99
9_L 234_T 1.367 0.98
182_A 187_V 1.363 0.98
11_N 94_Y 1.344 0.98
14_L 100_L 1.322 0.98
142_L 191_I 1.318 0.98
136_P 166_Q 1.316 0.98
2_K 34_T 1.308 0.98
142_L 146_I 1.282 0.97
40_T 238_V 1.278 0.97
41_G 48_L 1.272 0.97
80_R 83_L 1.267 0.97
7_E 94_Y 1.239 0.97
115_L 224_R 1.235 0.97
195_V 210_F 1.224 0.96
13_K 106_L 1.224 0.96
228_E 232_E 1.22 0.96
45_S 201_H 1.218 0.96
33_E 90_D 1.205 0.96
166_Q 188_D 1.196 0.96
51_E 241_I 1.195 0.96
116_L 146_I 1.193 0.96
39_V 55_L 1.193 0.96
140_L 144_S 1.192 0.96
39_V 60_V 1.185 0.95
40_T 61_I 1.182 0.95
135_M 141_E 1.179 0.95
80_R 87_L 1.178 0.95
59_A 92_N 1.173 0.95
3_N 59_A 1.16 0.95
183_A 206_Q 1.155 0.94
37_K 55_L 1.155 0.94
131_G 182_A 1.152 0.94
5_E 8_Q 1.15 0.94
124_I 128_V 1.143 0.94
171_C 190_F 1.142 0.94
44_A 60_V 1.142 0.94
111_Q 114_A 1.138 0.94
84_K 88_A 1.137 0.94
180_D 184_R 1.127 0.94
191_I 211_Y 1.127 0.94
114_A 121_M 1.12 0.93
139_G 189_A 1.118 0.93
133_L 136_P 1.112 0.93
51_E 54_R 1.106 0.93
150_L 218_T 1.091 0.92
24_P 28_Q 1.081 0.92
130_W 187_V 1.08 0.91
39_V 51_E 1.067 0.91
189_A 209_H 1.065 0.91
27_L 92_N 1.059 0.90
195_V 200_I 1.048 0.90
200_I 247_A 1.044 0.90
118_I 131_G 1.036 0.89
84_K 87_L 1.034 0.89
180_D 202_S 1.034 0.89
196_S 199_T 1.03 0.89
176_Q 196_S 1.023 0.88
111_Q 225_A 1.019 0.88
43_T 197_E 1.017 0.88
167_R 187_V 1.008 0.87
29_V 86_L 1.004 0.87
100_L 222_G 1.004 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1nmoA60.9961000.035Contact Map0.818
2gx8A30.98791000.046Contact Map0.787
2nydA20.98791000.047Contact Map0.817
2yybA20.97571000.065Contact Map0.786
2fywA30.98381000.067Contact Map0.752
3rxyA60.92311000.207Contact Map0.525
3tr9A40.842173.90.938Contact Map0.449
1tx2A20.801673.70.938Contact Map0.382
2bmbA10.785453.10.945Contact Map0.298
2dqwA20.809751.60.946Contact Map0.41

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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