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OPENSEQ.org

HDED - Protein HdeD
UniProt: P0AET5 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11495
Length: 190 (179)
Sequences: 668
Seq/Len: 3.73

HDED
Paralog alert: 0.07 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
25_Q 183_A 4.438 1.00
126_W 139_L 3.407 1.00
32_F 180_F 2.989 1.00
116_C 149_A 2.903 1.00
94_Y 98_R 2.624 1.00
35_G 173_I 2.332 1.00
113_G 117_V 2.325 1.00
136_W 140_V 2.324 1.00
119_G 142_G 2.319 1.00
65_I 86_A 2.174 1.00
139_L 143_V 2.162 1.00
55_A 59_C 2.081 1.00
25_Q 29_V 2.033 1.00
135_S 139_L 1.805 0.99
33_I 37_L 1.735 0.99
46_G 104_I 1.693 0.99
28_A 180_F 1.68 0.99
38_C 45_S 1.639 0.99
21_R 187_V 1.579 0.98
21_R 184_S 1.562 0.98
22_R 26_F 1.562 0.98
96_F 103_G 1.493 0.97
68_L 83_F 1.426 0.96
68_L 86_A 1.406 0.95
109_A 113_G 1.4 0.95
54_G 93_G 1.386 0.95
119_G 145_D 1.378 0.95
123_L 142_G 1.369 0.95
61_G 90_L 1.363 0.94
147_V 151_I 1.311 0.93
151_I 169_G 1.289 0.92
123_L 139_L 1.277 0.91
28_A 176_A 1.275 0.91
143_V 147_V 1.269 0.91
32_F 173_I 1.266 0.91
130_R 135_S 1.263 0.91
140_V 143_V 1.257 0.91
83_F 87_V 1.241 0.90
108_A 162_T 1.233 0.89
131_S 135_S 1.226 0.89
126_W 135_S 1.209 0.88
141_I 165_S 1.203 0.88
25_Q 184_S 1.2 0.88
58_I 147_V 1.194 0.87
42_P 49_L 1.191 0.87
54_G 172_L 1.19 0.87
184_S 187_V 1.185 0.87
58_I 93_G 1.174 0.86
134_G 137_L 1.169 0.86
108_A 160_S 1.165 0.85
31_L 175_S 1.155 0.85
118_A 122_R 1.145 0.84
21_R 25_Q 1.123 0.82
60_S 172_L 1.122 0.82
42_P 169_G 1.107 0.81
29_V 147_V 1.105 0.81
50_S 104_I 1.082 0.79
31_L 115_F 1.073 0.78
89_Y 114_L 1.073 0.78
123_L 146_I 1.068 0.78
64_L 86_A 1.066 0.78
50_S 57_L 1.061 0.77
103_G 115_F 1.061 0.77
126_W 142_G 1.054 0.77
27_I 172_L 1.054 0.77
31_L 56_L 1.043 0.76
46_G 165_S 1.034 0.75
120_V 124_M 1.033 0.75
25_Q 180_F 1.032 0.74
32_F 182_F 1.032 0.74
50_S 111_I 1.032 0.74
122_R 171_E 1.029 0.74
143_V 154_G 1.029 0.74
39_I 169_G 1.023 0.74
147_V 162_T 1.016 0.73
34_V 172_L 1.012 0.72
115_F 145_D 1.011 0.72
33_I 98_R 1.007 0.72
108_A 165_S 1.001 0.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4ev6A50.38428.90.934Contact Map0.579
4i0uA100.37378.60.934Contact Map0.636
4j05A20.84213.90.944Contact Map0.11
2wswA10.35793.50.946Contact Map0
2kogA10.22113.40.946Contact Map0.046
3ux4A30.72113.30.946Contact Map0.196
3wdoA10.89473.10.947Contact Map0.173
1ku1A20.26842.20.951Contact Map0.002
3o7qA10.86841.90.952Contact Map0.049
2xq2A10.37371.90.953Contact Map0.335

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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