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OPENSEQ.org
LPTE - LPS-assembly lipoprotein LptE
UniProt: P0ADC1 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10855
Length: 193 (171)
Sequences: 304
Seq/Len: 1.78
LPTE
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
85_D 99_Q 2.104 0.99
84_K 140_Q 2.016 0.99
55_L 60_V 1.888 0.98
168_R 171_E 1.707 0.95
82_I 144_V 1.654 0.94
87_A 155_L 1.641 0.94
66_E 171_E 1.61 0.93
167_I 170_D 1.575 0.92
166_D 170_D 1.553 0.91
136_K 139_E 1.546 0.91
167_I 172_E 1.452 0.87
86_T 134_L 1.447 0.87
66_E 170_D 1.43 0.86
95_T 98_Y 1.421 0.86
66_E 172_E 1.42 0.85
168_R 172_E 1.417 0.85
107_T 156_I 1.412 0.85
88_S 101_I 1.412 0.85
93_G 154_Q 1.388 0.84
80_V 148_Y 1.387 0.84
36_M 159_L 1.38 0.83
84_K 98_Y 1.375 0.83
36_M 62_L 1.367 0.82
167_I 171_E 1.362 0.82
22_H 143_I 1.352 0.81
17_A 56_R 1.34 0.81
66_E 167_I 1.339 0.81
97_E 157_R 1.335 0.80
3_Y 10_S 1.3 0.78
21_W 148_Y 1.296 0.78
44_N 148_Y 1.279 0.76
21_W 25_D 1.278 0.76
66_E 168_R 1.256 0.74
76_R 107_T 1.25 0.74
51_V 77_L 1.241 0.73
5_A 8_L 1.24 0.73
129_N 151_A 1.236 0.73
88_S 129_N 1.228 0.72
18_G 94_Q 1.227 0.72
3_Y 171_E 1.225 0.72
106_A 138_N 1.221 0.71
107_T 117_P 1.201 0.70
96_A 127_F 1.201 0.70
147_M 151_A 1.2 0.69
106_A 127_F 1.189 0.68
10_S 14_L 1.183 0.68
102_M 147_M 1.179 0.67
117_P 155_L 1.179 0.67
94_Q 160_P 1.178 0.67
3_Y 167_I 1.178 0.67
49_R 86_T 1.165 0.66
125_S 143_I 1.163 0.66
25_D 107_T 1.157 0.65
96_A 147_M 1.154 0.65
46_P 109_L 1.147 0.64
88_S 128_D 1.132 0.63
3_Y 168_R 1.115 0.61
145_K 156_I 1.106 0.60
9_L 89_V 1.105 0.60
8_L 11_L 1.103 0.60
126_F 146_E 1.103 0.60
24_R 93_G 1.102 0.60
96_A 139_E 1.1 0.60
16_T 51_V 1.098 0.59
96_A 134_L 1.089 0.58
90_F 93_G 1.087 0.58
58_N 139_E 1.081 0.58
132_M 151_A 1.071 0.57
75_L 92_N 1.07 0.56
166_D 172_E 1.064 0.56
126_F 129_N 1.064 0.56
102_M 151_A 1.063 0.56
26_T 104_V 1.059 0.55
126_F 151_A 1.052 0.54
89_V 128_D 1.052 0.54
128_D 136_K 1.044 0.54
3_Y 172_E 1.038 0.53
34_K 137_D 1.033 0.52
11_L 28_Q 1.03 0.52
35_V 106_A 1.028 0.52
54_Q 152_A 1.025 0.52
99_Q 138_N 1.025 0.52
40_S 43_P 1.024 0.51
78_G 102_M 1.021 0.51
21_W 143_I 1.011 0.50
93_G 99_Q 1.011 0.50
101_I 154_Q 1.01 0.50
124_R 147_M 1.009 0.50
63_L 133_A 1.006 0.50
5_A 171_E 1.002 0.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2r76A20.78761000.349Contact Map0.407
3bf2A10.7721000.37Contact Map0.307
2jxpA10.78241000.376Contact Map0.267
4kwyA20.709892.50.901Contact Map0.191
3onrA120.373136.40.94Contact Map0.031
2cc6A10.352328.80.943Contact Map0.233
2yizA40.357519.30.947Contact Map0.325
3zbiC140.2487180.948Contact Map0
2ux9A60.357516.30.949Contact Map0.351
2vxaA120.367916.10.949Contact Map0.342
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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