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OPENSEQ.org
NAPC - Cytochrome c-type protein NapC
UniProt: P0ABL5 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12060
Length: 200 (193)
Sequences: 389
Seq/Len: 2.02
NAPC
Paralog alert: 0.70 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
135_E 138_R 2.847 1.00
62_E 113_K 2.486 1.00
48_M 88_P 2.392 1.00
12_K 16_K 2.12 0.99
129_L 133_Q 2.076 0.99
142_N 145_Q 1.937 0.99
143_N 178_T 1.871 0.98
153_F 172_A 1.842 0.98
34_F 40_F 1.836 0.98
39_V 43_G 1.773 0.97
52_N 92_V 1.718 0.97
95_E 98_P 1.645 0.95
105_K 109_E 1.645 0.95
137_R 141_D 1.643 0.95
196_V 199_G 1.596 0.94
127_H 131_M 1.582 0.94
75_V 187_A 1.569 0.93
133_Q 137_R 1.511 0.92
169_H 178_T 1.508 0.92
119_D 123_K 1.487 0.91
102_R 109_E 1.478 0.90
58_I 68_Y 1.424 0.88
62_E 109_E 1.416 0.88
66_T 74_S 1.401 0.87
120_T 123_K 1.401 0.87
135_E 142_N 1.396 0.87
8_P 12_K 1.393 0.87
29_L 33_G 1.386 0.86
127_H 130_T 1.37 0.85
54_E 86_T 1.362 0.85
131_M 134_N 1.357 0.85
130_T 134_N 1.337 0.83
140_K 181_D 1.337 0.83
16_K 19_R 1.292 0.80
98_P 145_Q 1.283 0.80
117_V 127_H 1.272 0.79
10_L 14_L 1.259 0.78
48_M 107_S 1.256 0.78
108_K 112_G 1.249 0.77
101_I 104_L 1.237 0.76
158_T 170_D 1.228 0.75
195_E 199_G 1.222 0.75
96_F 100_M 1.217 0.75
85_A 89_D 1.204 0.73
192_D 197_E 1.199 0.73
143_N 176_G 1.195 0.73
25_A 28_T 1.184 0.72
24_L 29_L 1.182 0.71
97_V 101_I 1.172 0.71
161_Q 178_T 1.157 0.69
134_N 137_R 1.136 0.67
48_M 86_T 1.131 0.67
105_K 134_N 1.13 0.67
110_L 115_F 1.127 0.66
18_W 21_P 1.121 0.66
10_L 13_R 1.119 0.65
98_P 142_N 1.119 0.65
12_K 15_W 1.116 0.65
102_R 149_N 1.113 0.65
148_R 178_T 1.096 0.63
42_G 96_F 1.095 0.63
70_E 128_R 1.095 0.63
50_K 55_E 1.095 0.63
74_S 187_A 1.091 0.63
110_L 114_I 1.09 0.62
41_W 44_F 1.089 0.62
11_I 64_R 1.085 0.62
84_R 155_Y 1.082 0.62
58_I 86_T 1.077 0.61
48_M 110_L 1.073 0.61
51_A 110_L 1.072 0.60
153_F 158_T 1.068 0.60
169_H 173_V 1.068 0.60
41_W 83_V 1.067 0.60
98_P 118_I 1.065 0.60
122_Q 126_A 1.065 0.60
128_R 132_A 1.063 0.60
9_G 194_R 1.057 0.59
66_T 121_P 1.052 0.58
19_R 30_L 1.052 0.58
168_M 172_A 1.042 0.57
58_I 63_M 1.04 0.57
167_K 175_D 1.026 0.55
140_K 143_N 1.025 0.55
68_Y 72_M 1.022 0.55
138_R 142_N 1.018 0.55
148_R 161_Q 1.014 0.54
102_R 138_R 1.012 0.54
170_D 174_K 1.007 0.53
176_G 195_E 1.006 0.53
20_T 55_E 1.005 0.53
30_L 33_G 1.004 0.53
67_V 109_E 1.003 0.53
9_G 19_R 1.003 0.53
24_L 28_T 1.002 0.53
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2j7aC60.781000.54Contact Map0.343
3fo3A20.9599.80.729Contact Map0.147
1sp3A10.78599.70.752Contact Map0.166
4fasA30.83599.70.767Contact Map0.149
1oahA20.87599.60.783Contact Map0.108
2j7aA120.999.40.805Contact Map0.174
1fgjA20.7899.40.806Contact Map0.179
2ozyA10.6799.20.821Contact Map0.375
3ubrA20.8598.70.852Contact Map0.14
1jniA10.50598.40.866Contact Map0.099
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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