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OPENSEQ.org

YCAR - UPF0434 protein YcaR
UniProt: P0AAZ7 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14287
Length: 60 (58)
Sequences: 632
Seq/Len: 10.90

YCAR
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
26_E 51_R 4.186 1.00
29_C 32_D 3.405 1.00
14_C 32_D 3.001 1.00
14_C 29_C 2.57 1.00
19_W 30_K 2.459 1.00
21_N 24_K 2.159 1.00
35_A 51_R 1.821 1.00
20_Y 38_L 1.771 1.00
9_I 45_L 1.716 1.00
5_L 15_N 1.702 1.00
39_R 49_E 1.672 1.00
16_G 31_L 1.631 1.00
26_E 35_A 1.607 1.00
20_Y 25_Q 1.566 1.00
13_V 47_E 1.522 1.00
26_E 45_L 1.273 0.99
5_L 8_I 1.218 0.98
15_N 42_I 1.184 0.98
46_L 49_E 1.156 0.97
10_A 15_N 1.085 0.96
36_F 47_E 1.065 0.95
28_I 53_L 1.047 0.94
9_I 17_K 1.025 0.93
13_V 48_T 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2hf1A2199.80.109Contact Map0.788
2jr6A1199.80.11Contact Map0.496
2js4A1199.80.114Contact Map0.574
2pk7A2199.80.118Contact Map0.779
2jnyA1199.80.137Contact Map0.533
2k5rA1199.80.182Contact Map0.363
2kpiA10.866799.70.214Contact Map0.501
3q87A10.898.90.5Contact Map0.223
2j6aA10.998.80.526Contact Map0.196
1dl6A10.998.60.553Contact Map0.332

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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