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OPENSEQ.org

IOJAP - Ribosomal silencing factor RsfS
UniProt: P0AAT6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11255
Length: 105 (104)
Sequences: 1527
Seq/Len: 14.68

IOJAP
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
14_I 51_I 3.151 1.00
14_I 19_G 3.031 1.00
99_E 102_K 2.829 1.00
58_E 61_A 2.822 1.00
19_G 40_C 2.819 1.00
42_G 48_V 2.138 1.00
22_I 40_C 1.936 1.00
59_S 82_L 1.905 1.00
27_V 34_T 1.837 1.00
54_H 58_E 1.667 1.00
7_Q 11_I 1.618 1.00
76_D 91_Q 1.599 1.00
69_V 80_V 1.584 1.00
52_A 78_I 1.566 1.00
14_I 55_V 1.556 1.00
66_P 82_L 1.54 1.00
43_T 47_H 1.537 1.00
40_C 89_V 1.526 1.00
14_I 40_C 1.496 1.00
52_A 89_V 1.483 1.00
79_V 86_I 1.423 1.00
70_E 79_V 1.395 0.99
10_V 82_L 1.394 0.99
56_V 69_V 1.389 0.99
6_L 59_S 1.383 0.99
76_D 94_S 1.379 0.99
9_F 62_A 1.377 0.99
9_F 13_K 1.339 0.99
13_K 54_H 1.304 0.99
91_Q 94_S 1.275 0.99
67_L 83_G 1.27 0.99
39_I 100_L 1.265 0.99
10_V 38_I 1.26 0.99
7_Q 38_I 1.254 0.99
51_I 89_V 1.25 0.99
59_S 64_L 1.242 0.98
21_D 41_T 1.239 0.98
11_I 15_D 1.221 0.98
24_A 38_I 1.22 0.98
27_V 31_S 1.183 0.98
47_H 50_S 1.182 0.98
53_D 72_E 1.178 0.98
56_V 80_V 1.171 0.98
48_V 89_V 1.151 0.97
38_I 85_V 1.133 0.97
42_G 51_I 1.128 0.97
13_K 55_V 1.125 0.97
47_H 51_I 1.104 0.96
75_A 78_I 1.083 0.96
57_Q 61_A 1.08 0.95
15_D 22_I 1.079 0.95
49_M 75_A 1.046 0.94
11_I 22_I 1.043 0.94
37_M 88_H 1.036 0.94
54_H 57_Q 1.02 0.93
57_Q 60_R 1.02 0.93
37_M 86_I 1.016 0.93
19_G 51_I 1.013 0.93
48_V 91_Q 1.012 0.93
72_E 78_I 1.01 0.93
8_D 11_I 1.002 0.92
48_V 75_A 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2id1A211000.012Contact Map0.841
2o5aA211000.013Contact Map0.942
3upsA111000.027Contact Map0.882
2qipA10.828634.50.912Contact Map0.126
3aszA20.609518.60.923Contact Map0.295
2wp4A20.771412.40.929Contact Map0.511
4ht5A60.666710.90.931Contact Map0.313
3fchA20.59059.50.933Contact Map0.292
3nbmA10.81990.933Contact Map0.132
3ct4A30.83818.90.934Contact Map0.273

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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