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OPENSEQ.org
YGFB - UPF0149 protein YgfB
UniProt: P0A8C4 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11323
Length: 192 (191)
Sequences: 265
Seq/Len: 1.39
YGFB
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
14_N 26_P 2.865 1.00
139_N 142_Q 2.809 1.00
160_E 164_Y 2.444 1.00
105_L 165_V 2.181 0.99
127_T 175_T 2.087 0.98
157_S 160_E 2.069 0.98
10_Y 27_A 1.692 0.92
113_L 138_R 1.639 0.91
71_M 161_I 1.613 0.90
153_E 157_S 1.589 0.89
109_V 172_C 1.516 0.85
81_D 161_I 1.485 0.84
130_T 172_C 1.473 0.83
96_V 100_D 1.471 0.83
188_K 191_L 1.459 0.82
133_A 168_A 1.441 0.81
158_L 162_I 1.428 0.80
26_P 169_A 1.394 0.78
88_L 161_I 1.359 0.76
131_G 135_D 1.354 0.75
101_R 142_Q 1.352 0.75
136_D 140_I 1.337 0.74
140_I 164_Y 1.323 0.73
43_D 159_E 1.319 0.73
68_L 132_E 1.298 0.71
102_A 137_L 1.297 0.71
85_L 133_A 1.288 0.70
75_T 92_D 1.278 0.69
37_I 75_T 1.263 0.68
44_S 95_D 1.25 0.67
71_M 75_T 1.221 0.64
89_Y 97_S 1.219 0.64
45_S 116_L 1.216 0.63
34_S 37_I 1.202 0.62
130_T 155_E 1.202 0.62
88_L 117_G 1.199 0.62
99_F 103_D 1.188 0.61
101_R 155_E 1.187 0.61
81_D 86_F 1.169 0.59
57_G 172_C 1.167 0.59
115_G 144_G 1.163 0.58
77_D 94_D 1.16 0.58
26_P 104_A 1.159 0.58
86_F 160_E 1.145 0.57
105_L 140_I 1.141 0.56
90_L 162_I 1.14 0.56
11_N 66_Q 1.138 0.56
7_M 158_L 1.128 0.55
89_Y 155_E 1.127 0.55
116_L 137_L 1.126 0.55
142_Q 166_R 1.125 0.55
138_R 141_A 1.113 0.53
95_D 130_T 1.111 0.53
140_I 156_M 1.108 0.53
101_R 104_A 1.097 0.52
109_V 156_M 1.097 0.52
128_G 131_G 1.096 0.52
8_P 74_A 1.096 0.52
98_V 187_Q 1.095 0.52
79_L 169_A 1.089 0.51
17_L 20_Q 1.087 0.51
36_M 139_N 1.083 0.50
60_F 161_I 1.08 0.50
123_L 126_V 1.079 0.50
18_N 44_S 1.077 0.50
117_G 161_I 1.075 0.50
8_P 169_A 1.07 0.49
16_Y 167_V 1.068 0.49
124_D 180_Q 1.067 0.49
81_D 84_F 1.062 0.48
106_A 143_L 1.061 0.48
29_M 172_C 1.058 0.48
85_L 129_E 1.05 0.47
33_I 118_V 1.046 0.47
82_D 97_S 1.045 0.47
42_D 158_L 1.045 0.47
28_E 40_G 1.044 0.46
25_T 29_M 1.043 0.46
17_L 172_C 1.041 0.46
37_I 41_N 1.039 0.46
60_F 68_L 1.038 0.46
18_N 92_D 1.037 0.46
68_L 75_T 1.037 0.46
13_M 140_I 1.035 0.46
65_A 168_A 1.035 0.46
150_D 185_E 1.03 0.45
10_Y 110_N 1.029 0.45
128_G 141_A 1.023 0.44
57_G 60_F 1.016 0.44
49_L 134_I 1.014 0.43
50_L 90_L 1.012 0.43
45_S 134_I 1.011 0.43
27_A 156_M 1.008 0.43
12_E 21_G 1.006 0.43
126_V 176_F 1.004 0.42
17_L 64_L 1 0.42
12_E 42_D 1 0.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4gytA20.98441000.269Contact Map0.343
1izmA10.94791000.277Contact Map0.293
3ip4C10.28656.90.958Contact Map0.528
3h0lC80.2766.30.959Contact Map0.601
2ee7A10.31255.20.96Contact Map0.135
4gr2A20.56253.20.964Contact Map0.248
2kmfA10.41672.30.967Contact Map0.383
4lvpA10.4742.20.967Contact Map0.327
2jhpA10.51041.60.97Contact Map0.176
3jrtA10.4011.50.97Contact Map0.042
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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