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RL28 - 50S ribosomal protein L28
UniProt: P0A7M2 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10886
Length: 78 (78)
Sequences: 678
Seq/Len: 8.69

RL28
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
35_S 48_T 3.896 1.00
18_R 24_A 3.538 1.00
16_N 26_K 3.485 1.00
62_K 70_E 2.987 1.00
17_N 25_T 2.665 1.00
42_S 65_D 2.042 1.00
37_R 46_F 1.992 1.00
34_H 53_A 1.954 1.00
39_W 44_K 1.897 1.00
40_V 68_L 1.816 1.00
18_R 22_L 1.697 1.00
52_S 55_G 1.67 1.00
12_P 28_R 1.67 1.00
40_V 43_E 1.633 1.00
4_V 11_R 1.62 1.00
7_V 55_G 1.546 1.00
66_T 70_E 1.375 0.99
12_P 31_P 1.367 0.99
62_K 66_T 1.329 0.99
55_G 58_V 1.221 0.98
12_P 60_D 1.165 0.97
73_A 76_E 1.154 0.96
36_H 56_M 1.147 0.96
43_E 72_R 1.14 0.96
8_T 55_G 1.128 0.96
7_V 67_V 1.099 0.95
40_V 65_D 1.092 0.95
38_F 56_M 1.09 0.94
71_L 74_R 1.073 0.94
39_W 46_F 1.072 0.94
33_L 50_R 1.067 0.94
19_S 23_N 1.065 0.94
6_Q 49_L 1.049 0.93
43_E 65_D 1.047 0.93
35_S 50_R 1.019 0.91
74_R 78_Y 1.017 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kixX10.98721000.045Contact Map0.8
3bboY10.97441000.079Contact Map0.158
2jz6A10.923199.90.185Contact Map0.352
2zjrU10.717999.90.209Contact Map0.124
2jl6110.794999.90.221Contact Map0.679
3v2d110.961599.90.242Contact Map0.658
2zouA20.564180.915Contact Map0
1kptA20.39746.40.919Contact Map0.206
2qneA20.56413.40.929Contact Map0.251
2k5cA10.93592.90.931Contact Map0.043

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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