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OPENSEQ.org

FTSQ - Cell division protein FtsQ
UniProt: P06136 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10342
Length: 276 (241)
Sequences: 297
Seq/Len: 1.23

FTSQ
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
126_Y 139_D 3.446 1.00
209_L 223_F 2.062 0.98
33_T 117_D 1.999 0.97
196_R 213_R 1.985 0.97
100_E 109_V 1.942 0.96
132_W 251_G 1.839 0.94
119_L 128_P 1.818 0.94
107_K 126_Y 1.695 0.91
27_G 31_L 1.695 0.91
55_L 88_M 1.668 0.90
139_D 143_N 1.646 0.89
92_V 113_K 1.612 0.88
62_L 205_N 1.561 0.85
87_F 115_W 1.558 0.85
43_W 109_V 1.502 0.82
109_V 201_L 1.472 0.80
62_L 198_S 1.45 0.79
183_K 224_V 1.45 0.79
211_L 223_F 1.443 0.78
57_L 158_P 1.432 0.78
109_V 185_R 1.428 0.77
130_A 223_F 1.395 0.75
198_S 213_R 1.388 0.74
204_N 241_I 1.383 0.74
87_F 104_P 1.383 0.74
226_L 252_A 1.382 0.74
78_I 138_V 1.375 0.73
97_T 204_N 1.374 0.73
223_F 244_V 1.363 0.73
49_M 88_M 1.352 0.72
138_V 191_A 1.352 0.72
128_P 226_L 1.35 0.72
35_L 38_V 1.344 0.71
112_R 196_R 1.34 0.71
114_Q 120_K 1.336 0.70
163_P 193_M 1.299 0.67
56_P 181_L 1.295 0.67
74_I 176_E 1.284 0.66
19_R 22_G 1.276 0.65
121_I 193_M 1.274 0.65
198_S 227_Y 1.268 0.65
27_G 30_F 1.265 0.64
57_L 176_E 1.263 0.64
215_D 218_K 1.261 0.64
70_R 209_L 1.245 0.62
84_P 113_K 1.22 0.60
157_L 238_G 1.219 0.60
95_I 244_V 1.214 0.60
85_G 89_T 1.21 0.59
117_D 197_R 1.206 0.59
87_F 142_G 1.201 0.58
199_W 251_G 1.199 0.58
109_V 214_G 1.196 0.58
191_A 257_A 1.185 0.57
129_I 157_L 1.183 0.57
121_I 243_Y 1.181 0.56
219_R 244_V 1.163 0.55
224_V 228_P 1.154 0.54
129_I 140_A 1.144 0.53
70_R 210_N 1.143 0.53
248_Y 251_G 1.142 0.53
173_G 177_M 1.136 0.52
171_L 255_G 1.132 0.52
201_L 241_I 1.129 0.51
35_L 39_L 1.128 0.51
60_L 208_K 1.125 0.51
100_E 174_Y 1.122 0.51
96_Q 114_Q 1.118 0.50
92_V 171_L 1.116 0.50
36_T 39_L 1.113 0.50
110_S 164_E 1.108 0.49
18_R 22_G 1.105 0.49
196_R 199_W 1.102 0.49
51_D 256_W 1.098 0.48
181_L 248_Y 1.096 0.48
73_D 90_Q 1.095 0.48
56_P 251_G 1.085 0.47
75_R 79_L 1.084 0.47
63_T 121_I 1.084 0.47
132_W 199_W 1.083 0.47
20_N 23_T 1.083 0.47
89_T 124_V 1.081 0.47
56_P 220_L 1.08 0.47
87_F 227_Y 1.08 0.47
60_L 109_V 1.078 0.46
107_K 253_A 1.078 0.46
117_D 131_R 1.072 0.46
115_W 160_L 1.072 0.46
188_L 201_L 1.071 0.46
130_A 160_L 1.07 0.46
95_I 111_V 1.065 0.45
136_H 146_S 1.062 0.45
188_L 191_A 1.061 0.45
60_L 213_R 1.06 0.45
96_Q 118_E 1.058 0.44
88_M 95_I 1.056 0.44
72_D 106_I 1.056 0.44
147_V 198_S 1.052 0.44
86_T 194_T 1.047 0.43
34_V 61_V 1.042 0.43
212_G 219_R 1.04 0.43
139_D 177_M 1.039 0.43
190_E 220_L 1.038 0.42
203_L 219_R 1.035 0.42
27_G 34_V 1.028 0.42
209_L 222_R 1.026 0.41
75_R 119_L 1.024 0.41
138_V 220_L 1.022 0.41
187_T 244_V 1.022 0.41
123_L 226_L 1.017 0.40
162_G 212_G 1.016 0.40
102_R 220_L 1.012 0.40
199_W 213_R 1.009 0.40
209_L 249_D 1.008 0.40
18_R 43_W 1.007 0.40
99_I 253_A 1.005 0.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2vh2A20.88041000.433Contact Map0.271
2vh1A20.79711000.446Contact Map0.266
3j00Z10.351499.80.756Contact Map0.11
1yr1A10.405898.40.872Contact Map0.448
4k3bA10.83743.50.955Contact Map0.102
3efcA10.7717410.955Contact Map0.116
2qdfA10.771732.50.958Contact Map0.1
2x8xX10.7464310.958Contact Map0.057
3fymA10.159480.968Contact Map
2m8rA10.15947.80.968Contact Map0.605

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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