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mhcii (A, 1-100) (B, 1-100)

Genes: A B A+B
Length: 100 100 197
Sequences: 101 1902 30
Seq/Len: 1.01 19.02 0.15
MirrorTree (Pazo et al. 2001) 0.18
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show HHblits results] - Maybe useful in deciding what regions to trim.

Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.04 0.22 0.07
2 0.06 0.44 0.10
5 0.06 0.52 0.14
10 0.09 0.54 0.15
20 0.09 0.54 0.15
100 0.09 0.54 0.15
0.09 0.54 0.15
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!

GREMLIN results
  • ERROR: Not enough sequences to run GREMLIN analysis on (0.15 < 0.6).
WARNING: The input alignment may be corrupted!
  • For sequence B, there is a high ratio (0.54 > 0.4) of paralogs.

ID Seq/Len Name Options I_Prob Status
9027 0.15 mhcii (A, 1-100) (B, 1-100) Δgene:(1, 20) A:(1E-40, 8) B:(1E-40, 8) msa: HHblits (2015_06) Killed - Shared
9026 0.15 mhcii_ab (A, 1-100) (B, 1-100) Δgene:(1, 100) A:(1E-40, 8) B:(1E-40, 8) msa: HHblits (2015_06) Killed

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