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OPENSEQ.org

L25 - S19
UniProt: Q5SHZ1 - Q5SHP2
Length: 299
Sequences: 1207
Seq/Len: 4.39
I_Prob: 0.06
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2dZ 3v2eS 3v2fZContact Map
2j002j00S 2j01Z 2j02S 2j03ZContact Map
4juw4juwS 4juxZContact Map
4kix4kixV 4kiyS 4kizV 4kj0S 4kj1V 4kj2S 4kj3V 4kj4SContact Map
4kj54kj5V 4kj6S 4kj7V 4kj8S 4kj9V 4kjaS 4kjbV 4kjcSContact Map
3uyd3uydV 3uyeV 3uyfV 3uygVContact Map
4gd13r8sV 3r8tV 4gd1S 4gd2SContact Map
3ohc3ohcS 3ohdS 3ohjZ 3ohkZContact Map
3knh3knhS 3kniZ 3knjS 3knkZContact Map
3f1e3f1eS 3f1fZ 3f1gS 3f1hZContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
76_L 44_M 1.08 0.06
58_V 64_E 1.07 0.06
172_A 39_T 0.98 0.04
53_I 39_T 0.94 0.04
56_V 63_T 0.90 0.03
131_R 80_Y 0.85 0.03
108_P 79_T 0.82 0.03
148_D 11_V 0.80 0.02
111_V 6_K 0.79 0.02
122_R 57_H 0.77 0.02
89_F 55_K 0.77 0.02
110_G 53_N 0.76 0.02
114_G 53_N 0.75 0.02
4_R 10_F 0.75 0.02
171_I 45_V 0.75 0.02
116_V 55_K 0.75 0.02
178_E 41_V 0.74 0.02
76_L 39_T 0.74 0.02
45_D 44_M 0.73 0.02
117_L 57_H 0.73 0.02
47_V 28_K 0.72 0.02
109_A 44_M 0.72 0.02
147_G 5_L 0.71 0.02
60_E 75_A 0.71 0.02
73_Q 67_V 0.71 0.02
32_H 2_P 0.70 0.02
108_P 53_N 0.69 0.02
44_F 64_E 0.69 0.01
89_F 31_I 0.69 0.01
124_I 75_A 0.68 0.01
160_G 17_E 0.67 0.01
72_R 81_R 0.67 0.01
147_G 81_R 0.66 0.01
77_D 41_V 0.65 0.01
78_K 22_L 0.64 0.01
47_V 52_Y 0.64 0.01
93_D 63_T 0.64 0.01
18_L 88_K 0.63 0.01
116_V 28_K 0.63 0.01
115_G 53_N 0.63 0.01
167_P 62_I 0.61 0.01
85_H 80_Y 0.60 0.01
18_L 52_Y 0.60 0.01
183_L 62_I 0.60 0.01
3_Y 80_Y 0.60 0.01
62_P 80_Y 0.60 0.01
132_N 39_T 0.59 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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