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OPENSEQ.org
4HEA_J - 4HEA_L
UniProt: Q56225 - Q56227 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 782
Sequences: 1523
Seq/Len: 2.00
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3rkoBL:CM:DN:FJContact Map
4heaLT:MU:NV:JRContact Map
4he8FL:GM:IN:DJContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
62_A 369_G 1.07 0.00
107_G 408_L 0.93 0.00
49_R 87_I 0.92 0.00
70_V 247_T 0.91 0.00
108_L 260_Y 0.90 0.00
28_A 259_L 0.88 0.00
65_V 66_S 0.87 0.00
151_V 307_F 0.87 0.00
72_M 137_A 0.87 0.00
56_V 454_V 0.86 0.00
21_T 293_K 0.86 0.00
127_L 318_A 0.85 0.00
145_L 170_M 0.85 0.00
14_L 182_T 0.84 0.00
70_V 335_A 0.84 0.00
8_A 73_S 0.83 0.00
14_L 40_S 0.82 0.00
63_I 44_G 0.82 0.00
28_A 75_F 0.81 0.00
44_V 110_L 0.81 0.00
35_N 160_I 0.80 0.00
131_L 256_S 0.80 0.00
141_A 121_A 0.80 0.00
43_Y 281_G 0.79 0.00
25_A 247_T 0.78 0.00
10_F 456_A 0.78 0.00
58_V 450_A 0.78 0.00
152_V 229_A 0.78 0.00
27_H 162_N 0.77 0.00
154_V 223_M 0.77 0.00
139_L 378_L 0.76 0.00
13_L 260_Y 0.76 0.00
139_L 419_R 0.76 0.00
132_Y 260_Y 0.76 0.00
152_V 313_G 0.76 0.00
140_L 221_P 0.75 0.00
40_A 15_A 0.75 0.00
61_G 157_K 0.74 0.00
20_V 260_Y 0.74 0.00
143_G 270_I 0.74 0.00
17_V 541_L 0.73 0.00
101_A 424_V 0.73 0.00
34_L 173_M 0.73 0.00
95_L 83_V 0.73 0.00
13_L 269_A 0.73 0.00
148_A 162_N 0.72 0.00
53_F 65_F 0.72 0.00
41_G 259_L 0.72 0.00
150_T 305_Y 0.72 0.00
145_L 371_L 0.72 0.00
30_L 167_L 0.72 0.00
22_L 32_L 0.72 0.00
142_V 129_I 0.71 0.00
124_P 507_A 0.71 0.00
94_A 190_E 0.71 0.00
140_L 419_R 0.71 0.00
129_P 318_A 0.71 0.00
107_G 220_I 0.71 0.00
149_A 553_L 0.70 0.00
21_T 275_L 0.70 0.00
46_L 458_Y 0.70 0.00
31_A 318_A 0.70 0.00
32_L 82_G 0.70 0.00
17_V 506_W 0.70 0.00
19_V 206_G 0.70 0.00
39_L 286_F 0.70 0.00
154_V 331_L 0.70 0.00
133_G 38_L 0.70 0.00
7_L 447_H 0.70 0.00
127_L 256_S 0.69 0.00
70_V 133_G 0.69 0.00
7_L 571_A 0.69 0.00
28_A 534_V 0.69 0.00
10_F 182_T 0.69 0.00
62_A 98_D 0.69 0.00
46_L 446_N 0.68 0.00
47_D 438_A 0.68 0.00
127_L 343_L 0.68 0.00
17_V 264_P 0.68 0.00
63_I 452_G 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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