May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

4HEA_1 - 4HEA_M
UniProt: Q56222 - Q56228 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 907
Sequences: 1265
Seq/Len: 1.45
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea1B:MU:LT:NVContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
107_L 232_T 0.86 0.00
218_I 104_G 0.85 0.00
71_P 281_F 0.81 0.00
53_V 394_L 0.80 0.00
107_L 332_L 0.79 0.00
223_T 208_F 0.78 0.00
165_T 308_A 0.77 0.00
276_I 365_M 0.76 0.00
223_T 203_I 0.75 0.00
258_V 244_F 0.74 0.00
118_M 203_I 0.74 0.00
138_Y 157_L 0.74 0.00
419_D 307_G 0.73 0.00
127_A 290_L 0.73 0.00
254_I 313_Y 0.72 0.00
45_L 340_E 0.71 0.00
374_I 332_L 0.71 0.00
120_L 399_V 0.71 0.00
252_Y 290_L 0.70 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

Page generated in 0.2555 seconds.