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OPENSEQ.org
4HEA_2 - 4HEA_N
UniProt: Q56221 - Q56229 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 608
Sequences: 1293
Seq/Len: 2.20
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaNV:MU:LT:2CContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
91_A 349_F 1.00 0.00
96_L 286_L 0.96 0.00
130_T 240_S 0.94 0.00
150_L 354_R 0.94 0.00
80_L 293_G 0.91 0.00
96_L 419_V 0.90 0.00
131_A 209_L 0.86 0.00
77_K 257_L 0.85 0.00
117_F 224_L 0.83 0.00
119_V 75_G 0.82 0.00
155_A 404_A 0.81 0.00
82_V 298_V 0.81 0.00
153_L 143_A 0.81 0.00
150_L 254_A 0.81 0.00
154_L 355_A 0.80 0.00
85_T 140_G 0.80 0.00
98_D 286_L 0.79 0.00
137_N 243_V 0.78 0.00
78_Y 346_Y 0.77 0.00
126_G 368_S 0.77 0.00
80_L 182_G 0.77 0.00
93_A 223_L 0.75 0.00
152_A 212_A 0.74 0.00
80_L 199_V 0.74 0.00
95_E 183_L 0.74 0.00
153_L 53_Y 0.73 0.00
49_I 184_G 0.73 0.00
153_L 30_L 0.72 0.00
92_G 150_G 0.72 0.00
138_D 143_A 0.71 0.00
90_L 149_Y 0.71 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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