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OPENSEQ.org

4HEA_2 - 4HEA_K
UniProt: Q56221 - Q56226 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 276
Sequences: 1208
Seq/Len: 4.65
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea2C:KSContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
100_L 8_A 0.85 0.00
145_V 43_V 0.82 0.00
98_D 55_V 0.80 0.00
129_H 46_A 0.76 0.00
99_Y 58_L 0.75 0.00
153_L 87_V 0.74 0.00
136_V 40_L 0.73 0.00
80_L 81_H 0.72 0.00
131_A 63_V 0.72 0.00
119_V 78_I 0.71 0.00
140_P 27_V 0.71 0.00
119_V 43_V 0.71 0.00
145_V 12_A 0.71 0.00
102_E 6_T 0.70 0.00
126_G 47_R 0.69 0.00
82_V 24_A 0.68 0.00
131_A 55_V 0.68 0.00
149_R 82_R 0.68 0.00
153_L 39_N 0.68 0.00
120_Q 10_L 0.68 0.00
82_V 75_I 0.67 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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