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OPENSEQ.org
4HEA_5 - 4HEA_N
UniProt: Q56219 - Q56229 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 634
Sequences: 1535
Seq/Len: 2.73
I_Prob: 0.72
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaNV:MU:LT:5FContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
121_L 262_S 1.53 0.72
104_V 233_L 1.05 0.29
37_E 260_Y 0.89 0.17
29_L 97_L 0.87 0.15
124_I 336_L 0.87 0.15
37_E 222_A 0.86 0.15
55_L 84_F 0.85 0.14
103_T 196_T 0.84 0.14
91_R 382_V 0.84 0.13
34_F 276_G 0.82 0.12
101_L 357_A 0.81 0.12
44_M 138_L 0.80 0.12
90_V 344_G 0.80 0.11
122_F 238_A 0.79 0.11
34_F 386_P 0.79 0.11
150_Y 97_L 0.78 0.10
133_R 147_F 0.78 0.10
44_M 270_A 0.78 0.10
88_F 160_S 0.78 0.10
73_E 329_A 0.77 0.10
107_L 154_F 0.77 0.10
147_R 244_G 0.77 0.10
92_V 201_Q 0.77 0.10
54_G 414_L 0.76 0.10
119_Y 248_A 0.76 0.10
141_L 148_L 0.76 0.10
139_E 266_A 0.76 0.09
87_R 215_V 0.75 0.09
104_V 232_A 0.75 0.09
74_L 258_L 0.75 0.09
146_L 90_Y 0.74 0.09
31_R 70_A 0.74 0.09
124_I 209_L 0.74 0.09
118_V 183_L 0.74 0.09
141_L 338_P 0.73 0.08
76_S 332_S 0.73 0.08
140_D 222_A 0.73 0.08
137_T 146_F 0.73 0.08
88_F 57_G 0.72 0.08
120_D 205_T 0.72 0.08
54_G 115_S 0.72 0.08
107_L 336_L 0.71 0.08
102_P 298_V 0.71 0.08
130_P 356_G 0.71 0.08
43_A 242_V 0.71 0.08
121_L 101_T 0.71 0.08
87_R 194_F 0.71 0.08
120_D 246_L 0.71 0.07
94_V 121_L 0.71 0.07
39_A 370_V 0.71 0.07
71_V 103_H 0.71 0.07
110_S 383_F 0.70 0.07
109_G 370_V 0.70 0.07
94_V 188_A 0.69 0.07
51_D 110_A 0.69 0.07
102_P 272_A 0.69 0.07
48_F 367_T 0.69 0.07
124_I 232_A 0.69 0.07
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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