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OPENSEQ.org
4HEA_6 - 4HEA_N
UniProt: Q56218 - Q56229 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 608
Sequences: 1554
Seq/Len: 2.69
I_Prob: 0.01
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaNV:6G:MU:LTContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
151_V 410_L 1.01 0.01
130_V 154_F 0.89 0.00
103_K 118_L 0.89 0.00
30_W 226_V 0.89 0.00
100_P 132_A 0.89 0.00
61_A 239_L 0.89 0.00
75_A 107_M 0.86 0.00
137_V 373_Y 0.84 0.00
125_Q 152_A 0.84 0.00
56_A 227_A 0.81 0.00
151_V 60_Q 0.81 0.00
103_K 249_L 0.80 0.00
103_K 111_L 0.78 0.00
60_L 154_F 0.77 0.00
152_M 241_V 0.77 0.00
100_P 104_L 0.76 0.00
130_V 89_L 0.74 0.00
106_I 107_M 0.74 0.00
61_A 260_Y 0.73 0.00
100_P 143_A 0.73 0.00
120_N 211_M 0.72 0.00
120_N 215_V 0.72 0.00
79_I 176_L 0.72 0.00
67_V 111_L 0.72 0.00
41_F 109_V 0.72 0.00
131_V 86_L 0.71 0.00
151_V 348_A 0.71 0.00
125_Q 380_L 0.71 0.00
148_I 293_G 0.71 0.00
113_S 152_A 0.71 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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