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OPENSEQ.org
4HEA_6 - 4HEA_K
UniProt: Q56218 - Q56226 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 276
Sequences: 1022
Seq/Len: 4.10
I_Prob: 0.55
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea6G:KS:JRContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
135_V 66_A 1.34 0.55
131_V 11_F 1.11 0.33
157_K 9_L 1.00 0.24
109_G 14_G 1.00 0.24
147_L 91_S 0.92 0.19
130_V 5_L 0.91 0.18
117_M 33_L 0.91 0.17
98_Q 37_A 0.90 0.17
117_M 26_L 0.85 0.14
154_L 71_G 0.81 0.12
91_V 7_S 0.81 0.12
53_S 47_R 0.80 0.11
85_S 61_I 0.79 0.11
151_V 57_A 0.77 0.10
25_E 24_A 0.77 0.10
137_V 72_L 0.76 0.10
154_L 68_V 0.76 0.10
117_M 41_S 0.74 0.09
128_D 6_T 0.74 0.09
110_A 46_A 0.73 0.09
107_S 30_S 0.72 0.08
127_V 82_R 0.72 0.08
117_M 46_A 0.72 0.08
39_A 12_A 0.72 0.08
68_F 42_L 0.71 0.08
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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