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OPENSEQ.org
L28 - S19
UniProt: P60494 - Q5SHP2
Length: 191
Sequences: 816
Seq/Len: 5.26
I_Prob: 0.05
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2d1 3v2eS 3v2f1Contact Map
2j002j00S 2j011 2j02S 2j031Contact Map
4juw4juwS 4jux1Contact Map
4kix4kixX 4kiyS 4kizX 4kj0S 4kj1X 4kj2S 4kj3X 4kj4SContact Map
4kj54kj5X 4kj6S 4kj7X 4kj8S 4kj9X 4kjaS 4kjbX 4kjcSContact Map
3uyd3uydV 3uyeZ 3uyfV 3uygZContact Map
4gd13r8sX 3r8tX 4gd1S 4gd2SContact Map
3knh3knhS 3kni1 3knjS 3knk1Contact Map
3ohc3ohcS 3ohdS 3ohj1 3ohk1Contact Map
3ohy3ohyS 3ohz1 3oi0S 3oi11Contact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
74_V 57_H 1.05 0.05
61_R 2_P 1.00 0.04
73_L 80_Y 0.95 0.04
69_K 65_N 0.94 0.04
20_R 86_E 0.81 0.02
35_T 41_V 0.80 0.02
53_V 6_K 0.78 0.02
10_K 43_E 0.76 0.02
74_V 55_K 0.76 0.02
42_Q 39_T 0.76 0.02
74_V 53_N 0.72 0.02
60_F 44_M 0.72 0.02
46_L 53_N 0.71 0.02
41_R 63_T 0.70 0.02
16_N 86_E 0.68 0.01
2_S 29_R 0.67 0.01
65_S 76_P 0.66 0.01
52_R 49_I 0.66 0.01
54_A 30_L 0.65 0.01
6_E 19_V 0.64 0.01
43_Y 5_L 0.63 0.01
68_P 35_S 0.63 0.01
18_I 17_E 0.61 0.01
10_K 63_T 0.61 0.01
16_N 22_L 0.60 0.01
11_R 10_F 0.59 0.01
48_K 28_K 0.59 0.01
20_R 34_W 0.59 0.01
13_I 27_E 0.58 0.01
37_I 20_L 0.58 0.01
68_P 22_L 0.58 0.01
62_V 62_I 0.57 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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