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OPENSEQ.org

L19 - S19
UniProt: P60490 - Q5SHP2
Length: 239
Sequences: 1020
Seq/Len: 4.93
I_Prob: 0.02
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2dT 3v2eS 3v2fTContact Map
2j002j00S 2j01T 2j02S 2j03TContact Map
4juw4juwS 4juxTContact Map
4kix4kixP 4kiyS 4kizP 4kj0S 4kj1P 4kj2S 4kj3P 4kj4SContact Map
4kj54kj5P 4kj6S 4kj7P 4kj8S 4kj9P 4kjaS 4kjbP 4kjcSContact Map
3uyd3uydV 3uyeR 3uyfV 3uygRContact Map
4gd13r8sP 3r8tP 4gd1S 4gd2SContact Map
3ohc3ohcS 3ohdS 3ohjT 3ohkTContact Map
3knh3knhS 3kniT 3knjS 3knkTContact Map
3f1e3f1eS 3f1fT 3f1gS 3f1hTContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
66_V 40_I 0.99 0.02
81_P 69_H 0.90 0.02
106_S 62_I 0.88 0.01
115_R 52_Y 0.85 0.01
98_K 57_H 0.85 0.01
9_L 75_A 0.83 0.01
70_V 78_R 0.80 0.01
39_R 53_N 0.79 0.01
97_A 81_R 0.79 0.01
75_I 76_P 0.79 0.01
92_G 32_K 0.77 0.01
42_I 11_V 0.77 0.01
105_L 76_P 0.77 0.01
100_Y 84_G 0.77 0.01
76_F 11_V 0.77 0.01
40_T 56_Q 0.77 0.01
34_V 27_E 0.76 0.01
34_V 20_L 0.75 0.01
49_V 5_L 0.73 0.01
11_E 32_K 0.73 0.01
100_Y 46_G 0.73 0.01
96_R 45_V 0.72 0.01
77_P 30_L 0.72 0.01
87_D 13_D 0.71 0.01
82_L 45_V 0.69 0.01
20_P 50_A 0.69 0.01
33_K 80_Y 0.69 0.01
106_S 19_V 0.69 0.01
50_I 89_A 0.68 0.01
109_E 43_E 0.67 0.01
96_R 51_V 0.67 0.01
65_K 2_P 0.66 0.01
82_L 29_R 0.66 0.01
34_V 88_K 0.66 0.01
46_E 39_T 0.66 0.01
65_K 10_F 0.65 0.01
16_R 63_T 0.65 0.01
53_R 5_L 0.65 0.01
12_S 52_Y 0.65 0.01
85_K 5_L 0.64 0.01
46_E 65_N 0.64 0.01
22_F 37_R 0.63 0.01
39_R 34_W 0.63 0.01
34_V 33_T 0.63 0.01
8_K 43_E 0.62 0.01
90_Q 82_G 0.62 0.01
80_S 22_L 0.61 0.01
39_R 49_I 0.61 0.01
81_P 66_M 0.61 0.01
62_T 80_Y 0.61 0.01
5_A 62_I 0.60 0.01
82_L 58_V 0.60 0.01
113_K 81_R 0.60 0.01
31_S 80_Y 0.57 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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