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OPENSEQ.org

HPPK - PANB
UniProt: P26281 - P31057
Length: 423
Sequences: 274
Seq/Len: 0.65
I_Prob: 0.00

HPPK - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Paralog alert: 0.11 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HPPK
PANB - 3-methyl-2-oxobutanoate hydroxymethyltransferase
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PANB
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
43_T 27_Y 1.43 0.00
90_W 209_D 1.27 0.00
118_D 146_I 1.26 0.00
74_T 130_A 1.26 0.00
51_Q 182_C 1.25 0.00
91_G 88_M 1.24 0.00
29_I 113_I 1.20 0.00
90_W 182_C 1.20 0.00
156_L 27_Y 1.19 0.00
8_I 219_F 1.16 0.00
126_L 92_T 1.14 0.00
144_L 199_V 1.14 0.00
151_R 17_K 1.09 0.00
119_M 239_D 1.09 0.00
55_L 256_Y 1.08 0.00
65_L 170_L 1.06 0.00
5_Y 102_T 1.03 0.00
7_A 252_E 1.03 0.00
23_L 262_S 1.02 0.00
54_Y 118_W 1.00 0.00
132_I 247_Y 1.00 0.00
90_W 13_K 0.99 0.00
88_E 244_V 0.97 0.00
143_M 38_L 0.97 0.00
134_P 259_E 0.96 0.00
73_H 38_L 0.96 0.00
60_A 150_Y 0.95 0.00
144_L 4_T 0.94 0.00
159_W 38_L 0.94 0.00
131_E 166_D 0.93 0.00
102_F 228_K 0.93 0.00
77_I 117_E 0.93 0.00
121_N 192_T 0.93 0.00
10_S 206_N 0.92 0.00
117_Y 73_R 0.92 0.00
20_N 165_S 0.91 0.00
91_G 209_D 0.91 0.00
92_P 231_K 0.90 0.00
40_F 82_L 0.90 0.00
85_R 263_F 0.90 0.00
62_E 245_R 0.89 0.00
159_W 130_A 0.88 0.00
159_W 20_A 0.88 0.00
135_E 228_K 0.88 0.00
15_P 29_F 0.87 0.00
106_V 191_I 0.87 0.00
48_P 208_T 0.87 0.00
119_M 158_E 0.86 0.00
102_F 131_V 0.86 0.00
101_L 99_N 0.86 0.00
102_F 27_Y 0.86 0.00
138_F 208_T 0.85 0.00
90_W 88_M 0.85 0.00
47_G 182_C 0.85 0.00
7_A 76_A 0.85 0.00
59_V 65_I 0.85 0.00
42_R 37_G 0.85 0.00
117_Y 146_I 0.85 0.00
113_T 187_L 0.85 0.00
15_P 130_A 0.85 0.00
7_A 95_Q 0.84 0.00
53_D 195_L 0.84 0.00
68_E 123_V 0.84 0.00
53_D 228_K 0.84 0.00
61_L 30_A 0.84 0.00
39_S 191_I 0.84 0.00
69_E 186_E 0.84 0.00
43_T 113_I 0.84 0.00
14_S 165_S 0.83 0.00
59_V 130_A 0.83 0.00
6_I 39_N 0.83 0.00
57_A 232_N 0.83 0.00
92_P 216_H 0.83 0.00
140_D 131_V 0.83 0.00
54_Y 90_Y 0.83 0.00
23_L 75_G 0.82 0.00
14_S 8_L 0.82 0.00
54_Y 168_L 0.82 0.00
18_Q 49_M 0.82 0.00
41_Y 108_A 0.82 0.00
31_E 96_A 0.82 0.00
15_P 134_C 0.82 0.00
125_M 41_M 0.81 0.00
16_L 135_G 0.81 0.00
8_I 111_V 0.81 0.00
30_P 32_L 0.81 0.00
42_R 254_G 0.81 0.00
69_E 124_Q 0.81 0.00
123_G 262_S 0.80 0.00
114_V 94_E 0.80 0.00
92_P 140_T 0.80 0.00
23_L 15_E 0.80 0.00
75_Q 119_L 0.80 0.00
82_G 210_G 0.80 0.00
63_T 28_S 0.79 0.00
119_M 219_F 0.79 0.00
137_V 85_L 0.79 0.00
91_G 13_K 0.79 0.00
53_D 126_L 0.79 0.00
92_P 5_T 0.79 0.00
125_M 3_P 0.79 0.00
34_I 235_A 0.79 0.00
113_T 193_E 0.79 0.00
143_M 168_L 0.79 0.00
37_V 250_E 0.79 0.00
88_E 88_M 0.79 0.00
102_F 245_R 0.79 0.00
106_V 124_Q 0.78 0.00
155_K 2_K 0.78 0.00
149_H 195_L 0.78 0.00
10_S 183_V 0.78 0.00
46_L 24_A 0.78 0.00
74_T 77_P 0.77 0.00
59_V 256_Y 0.77 0.00
5_Y 79_C 0.77 0.00
44_P 222_T 0.77 0.00
101_L 192_T 0.77 0.00
89_R 261_H 0.77 0.00
84_V 111_V 0.77 0.00
46_L 106_A 0.77 0.00
147_I 163_L 0.77 0.00
119_M 180_L 0.77 0.00
15_P 199_V 0.77 0.00
39_S 189_K 0.77 0.00
87_A 185_V 0.77 0.00
119_M 22_I 0.76 0.00
132_I 164_L 0.76 0.00
85_R 140_T 0.76 0.00
143_M 225_H 0.76 0.00
88_E 66_A 0.76 0.00
59_V 62_V 0.76 0.00
7_A 97_F 0.76 0.00
23_L 96_A 0.76 0.00
62_E 121_E 0.76 0.00
8_I 245_R 0.76 0.00
92_P 247_Y 0.76 0.00
33_H 192_T 0.76 0.00
95_L 175_A 0.76 0.00
105_E 192_T 0.75 0.00
46_L 56_S 0.75 0.00
118_D 230_A 0.75 0.00
158_K 43_V 0.75 0.00
40_F 161_D 0.75 0.00
144_L 63_A 0.75 0.00
91_G 182_C 0.75 0.00
148_L 2_K 0.75 0.00
136_L 263_F 0.75 0.00
140_D 208_T 0.75 0.00
81_Q 170_L 0.75 0.00
102_F 253_S 0.75 0.00
133_A 95_Q 0.75 0.00
125_M 130_A 0.75 0.00
77_I 244_V 0.74 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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