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OPENSEQ.org

DYR - TYSY
UniProt: P0ABQ4 - P0A884
Length: 423
Sequences: 739
Seq/Len: 1.75
I_Prob: 0.00

DYR - Dihydrofolate reductase
Paralog alert: 0.09 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: DYR
TYSY - Thymidylate synthase
Paralog alert: 0.03 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: TYSY
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
17_E 193_D 1.08 0.00
119_V 200_V 0.86 0.00
93_V 120_K 0.85 0.00
97_G 136_G 0.83 0.00
62_L 6_E 0.83 0.00
85_C 135_V 0.81 0.00
98_R 251_G 0.81 0.00
110_L 200_V 0.80 0.00
32_K 89_D 0.79 0.00
63_S 229_K 0.78 0.00
101_E 221_S 0.78 0.00
47_W 142_A 0.73 0.00
105_P 226_P 0.72 0.00
156_L 239_I 0.72 0.00
50_I 89_D 0.71 0.00
21_P 129_I 0.71 0.00
6_A 236_P 0.70 0.00
4_L 45_V 0.67 0.00
29_A 187_M 0.67 0.00
6_A 254_P 0.66 0.00
153_F 202_T 0.66 0.00
9_A 247_F 0.66 0.00
78_V 49_R 0.65 0.00
115_I 87_N 0.65 0.00
98_R 237_E 0.65 0.00
36_L 239_I 0.64 0.00
77_S 109_I 0.63 0.00
135_S 208_L 0.63 0.00
29_A 103_T 0.63 0.00
78_V 248_E 0.61 0.00
40_V 2_K 0.61 0.00
62_L 135_V 0.61 0.00
63_S 149_F 0.60 0.00
6_A 45_V 0.60 0.00
100_Y 86_E 0.60 0.00
56_G 105_D 0.60 0.00
63_S 40_D 0.60 0.00
61_I 185_V 0.60 0.00
52_R 161_C 0.59 0.00
115_I 17_Q 0.59 0.00
118_E 251_G 0.59 0.00
37_N 88_G 0.59 0.00
118_E 81_D 0.58 0.00
23_N 192_C 0.58 0.00
108_Q 156_D 0.58 0.00
64_S 56_I 0.58 0.00
75_V 257_G 0.57 0.00
86_G 13_D 0.57 0.00
48_E 2_K 0.57 0.00
81_A 224_P 0.57 0.00
99_V 241_D 0.57 0.00
125_F 201_W 0.57 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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