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OPENSEQ.org
HEM1 - HEM2
UniProt: P0A6X1 - P0ACB2
Length: 742
Sequences: 456
Seq/Len: 0.62
I_Prob: 0.00
HEM1 - Glutamyl-tRNA reductase
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM1 		HEM2 - Delta-aminolevulinic acid dehydratase
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM2
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
21_V 45_K 1.21 0.00
220_Q 26_L 1.18 0.00
106_G 39_E 1.18 0.00
46_V 32_V 1.15 0.00
69_L 145_E 1.10 0.00
287_P 184_F 1.06 0.00
173_A 20_M 1.06 0.00
9_N 24_T 1.06 0.00
137_E 277_A 1.04 0.00
194_I 188_A 1.03 0.00
257_I 190_M 1.03 0.00
58_S 119_T 1.02 0.00
158_I 85_T 1.01 0.00
132_H 46_A 1.01 0.00
128_S 32_V 1.01 0.00
286_E 50_M 1.00 0.00
105_S 156_A 1.00 0.00
284_D 138_V 0.99 0.00
91_H 124_Y 0.99 0.00
231_I 277_A 0.99 0.00
101_M 74_R 0.98 0.00
34_S 193_S 0.96 0.00
188_V 200_F 0.96 0.00
8_I 73_I 0.95 0.00
246_I 145_E 0.95 0.00
345_I 200_F 0.95 0.00
200_H 255_I 0.95 0.00
97_V 26_L 0.93 0.00
245_I 50_M 0.92 0.00
185_V 138_V 0.92 0.00
179_S 300_S 0.91 0.00
418_E 133_L 0.91 0.00
249_S 257_R 0.91 0.00
221_I 277_A 0.90 0.00
355_V 300_S 0.90 0.00
8_I 126_S 0.89 0.00
412_R 143_T 0.89 0.00
218_R 184_F 0.88 0.00
74_C 55_R 0.88 0.00
87_S 277_A 0.88 0.00
180_L 272_V 0.88 0.00
81_E 243_C 0.87 0.00
400_A 320_K 0.87 0.00
153_R 117_S 0.87 0.00
373_A 308_L 0.87 0.00
105_S 29_N 0.87 0.00
21_V 55_R 0.87 0.00
6_L 261_E 0.86 0.00
44_G 162_I 0.86 0.00
130_K 177_Q 0.86 0.00
101_M 19_A 0.86 0.00
387_R 235_L 0.86 0.00
16_S 193_S 0.85 0.00
18_R 43_D 0.85 0.00
238_E 187_T 0.85 0.00
362_K 235_L 0.85 0.00
322_E 185_K 0.85 0.00
72_W 100_A 0.85 0.00
206_V 317_L 0.84 0.00
281_V 92_A 0.84 0.00
217_E 83_H 0.84 0.00
194_I 114_I 0.83 0.00
234_S 206_E 0.83 0.00
156_T 287_A 0.83 0.00
256_I 75_S 0.83 0.00
245_I 175_I 0.83 0.00
186_L 139_D 0.83 0.00
80_N 256_V 0.83 0.00
276_L 188_A 0.83 0.00
105_S 307_D 0.83 0.00
15_V 20_M 0.83 0.00
38_Q 256_V 0.83 0.00
156_T 51_P 0.82 0.00
170_C 285_A 0.82 0.00
337_R 300_S 0.82 0.00
153_R 119_T 0.81 0.00
35_L 258_E 0.81 0.00
158_I 211_A 0.81 0.00
48_S 257_R 0.81 0.00
212_A 258_E 0.81 0.00
128_S 206_E 0.81 0.00
377_M 217_K 0.81 0.00
79_L 229_A 0.81 0.00
301_D 17_L 0.80 0.00
175_Q 193_S 0.80 0.00
318_A 277_A 0.80 0.00
165_V 258_E 0.80 0.00
100_L 277_A 0.80 0.00
322_E 172_V 0.80 0.00
205_K 94_R 0.80 0.00
170_C 133_L 0.79 0.00
204_H 31_L 0.79 0.00
246_I 288_I 0.79 0.00
132_H 83_H 0.79 0.00
201_L 129_H 0.79 0.00
240_L 92_A 0.79 0.00
344_T 255_I 0.79 0.00
41_V 231_R 0.79 0.00
257_I 261_E 0.78 0.00
373_A 199_S 0.78 0.00
158_I 172_V 0.78 0.00
141_M 196_F 0.78 0.00
388_L 317_L 0.78 0.00
192_E 147_L 0.78 0.00
57_L 255_I 0.78 0.00
210_I 259_L 0.78 0.00
254_L 310_F 0.78 0.00
187_L 117_S 0.78 0.00
153_R 154_A 0.78 0.00
55_L 288_I 0.78 0.00
15_V 319_E 0.77 0.00
18_R 147_L 0.77 0.00
143_Q 315_L 0.77 0.00
141_M 200_F 0.77 0.00
8_I 279_I 0.77 0.00
288_E 279_I 0.77 0.00
159_G 197_A 0.77 0.00
106_G 11_L 0.76 0.00
216_R 152_V 0.76 0.00
242_E 293_V 0.76 0.00
379_D 317_L 0.76 0.00
20_R 187_T 0.76 0.00
304_Q 156_A 0.76 0.00
308_S 193_S 0.76 0.00
329_T 298_L 0.76 0.00
143_Q 64_E 0.76 0.00
44_G 253_L 0.76 0.00
119_G 97_G 0.76 0.00
335_W 57_P 0.76 0.00
119_G 98_L 0.76 0.00
48_S 89_G 0.75 0.00
209_M 188_A 0.75 0.00
282_P 85_T 0.75 0.00
362_K 8_P 0.75 0.00
121_V 243_C 0.75 0.00
124_A 259_L 0.75 0.00
406_E 172_V 0.75 0.00
352_A 121_F 0.75 0.00
255_P 108_Q 0.75 0.00
168_A 73_I 0.74 0.00
297_L 252_Y 0.74 0.00
112_L 255_I 0.74 0.00
408_L 46_A 0.74 0.00
20_R 83_H 0.74 0.00
335_W 107_K 0.74 0.00
333_M 313_F 0.74 0.00
79_L 226_R 0.74 0.00
80_N 31_L 0.74 0.00
209_M 152_V 0.74 0.00
45_V 106_C 0.74 0.00
152_V 235_L 0.74 0.00
18_R 111_P 0.74 0.00
93_D 255_I 0.74 0.00
20_R 277_A 0.73 0.00
71_R 92_A 0.73 0.00
233_L 237_E 0.73 0.00
18_R 171_Q 0.73 0.00
45_V 237_E 0.73 0.00
31_A 316_D 0.73 0.00
47_L 300_S 0.73 0.00
186_L 61_L 0.73 0.00
85_R 92_A 0.73 0.00
125_F 77_M 0.73 0.00
392_P 64_E 0.73 0.00
188_V 276_Y 0.73 0.00
213_N 71_A 0.73 0.00
361_A 279_I 0.73 0.00
272_Q 251_A 0.73 0.00
101_M 313_F 0.72 0.00
199_R 74_R 0.72 0.00
393_T 212_L 0.72 0.00
139_E 106_C 0.72 0.00
130_K 206_E 0.72 0.00
11_K 154_A 0.72 0.00
6_L 238_A 0.72 0.00
59_V 24_T 0.72 0.00
277_V 113_M 0.72 0.00
100_L 129_H 0.72 0.00
231_I 268_G 0.72 0.00
285_V 16_A 0.72 0.00
238_E 126_S 0.72 0.00
329_T 187_T 0.72 0.00
256_I 59_K 0.72 0.00
390_H 55_R 0.72 0.00
246_I 258_E 0.72 0.00
188_V 149_K 0.71 0.00
178_E 255_I 0.71 0.00
293_A 78_T 0.71 0.00
68_A 102_M 0.71 0.00
42_Q 194_T 0.71 0.00
299_S 190_M 0.71 0.00
169_A 249_A 0.71 0.00
44_G 31_L 0.71 0.00
180_L 151_A 0.71 0.00
215_T 284_L 0.71 0.00
100_L 102_M 0.71 0.00
359_L 235_L 0.71 0.00
277_V 187_T 0.71 0.00
300_V 139_D 0.71 0.00
247_I 233_S 0.71 0.00
203_E 116_M 0.71 0.00
289_V 91_D 0.71 0.00
128_S 191_S 0.71 0.00
359_L 196_F 0.70 0.00
258_G 149_K 0.70 0.00
198_A 200_F 0.70 0.00
79_L 258_E 0.70 0.00
357_D 238_A 0.70 0.00
325_V 90_S 0.70 0.00
156_T 50_M 0.70 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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