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OPENSEQ.org

3MML_A - 3MML_B
PDB: 3MML Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 498
Sequences: 1067
Seq/Len: 2.25
I_Prob: 0.92
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
254_T 124_F 1.83 0.92
265_E 10_D 1.79 0.91
230_G 49_L 1.55 0.82
229_E 44_A 1.50 0.78
241_N 148_E 1.36 0.68
22_G 40_D 1.07 0.39
237_Q 92_Y 1.04 0.35
237_Q 133_Y 1.04 0.35
265_E 11_Q 1.03 0.34
229_E 47_T 1.03 0.34
229_E 128_A 1.02 0.33
252_P 164_F 1.01 0.32
28_V 187_F 0.96 0.27
57_V 157_A 0.95 0.26
28_V 195_A 0.95 0.26
196_R 112_I 0.95 0.26
180_V 7_N 0.94 0.25
134_D 124_F 0.90 0.22
211_R 151_T 0.88 0.20
155_H 50_V 0.87 0.19
183_P 6_H 0.86 0.18
228_S 176_W 0.86 0.18
229_E 161_A 0.85 0.18
237_Q 156_G 0.85 0.18
28_V 194_P 0.84 0.17
232_T 51_K 0.83 0.16
183_P 124_F 0.83 0.16
156_T 80_P 0.83 0.16
188_F 179_I 0.83 0.16
124_V 184_A 0.83 0.16
228_S 145_R 0.82 0.16
122_I 192_D 0.81 0.15
116_L 205_F 0.81 0.15
254_T 133_Y 0.81 0.15
230_G 43_P 0.80 0.14
251_H 164_F 0.79 0.14
217_L 186_M 0.79 0.14
29_T 128_A 0.79 0.14
251_H 45_A 0.79 0.14
29_T 146_R 0.79 0.14
257_Y 149_P 0.79 0.13
253_V 164_F 0.78 0.13
49_P 25_A 0.78 0.13
177_L 11_Q 0.78 0.13
227_P 164_F 0.77 0.12
252_P 45_A 0.77 0.12
99_D 36_L 0.77 0.12
266_E 10_D 0.77 0.12
33_A 90_V 0.77 0.12
186_D 46_R 0.77 0.12
260_I 133_Y 0.76 0.12
26_M 188_D 0.76 0.12
194_L 110_Q 0.75 0.12
53_A 204_Q 0.75 0.12
101_Q 188_D 0.75 0.12
110_S 13_L 0.75 0.11
238_V 159_A 0.75 0.11
265_E 53_A 0.75 0.11
242_G 133_Y 0.75 0.11
229_E 14_L 0.75 0.11
227_P 46_R 0.75 0.11
226_L 44_A 0.74 0.11
232_T 49_L 0.73 0.10
6_V 117_G 0.73 0.10
252_P 135_V 0.73 0.10
254_T 44_A 0.73 0.10
193_I 141_L 0.73 0.10
262_V 8_Y 0.72 0.10
141_P 104_T 0.72 0.10
229_E 124_F 0.71 0.09
237_Q 172_S 0.71 0.09
190_D 209_G 0.71 0.09
26_M 195_A 0.70 0.09
265_E 54_G 0.70 0.09
261_G 155_A 0.70 0.09
33_A 199_P 0.69 0.09
146_P 15_L 0.69 0.09
199_W 16_E 0.69 0.09
258_P 176_W 0.69 0.09
45_L 205_F 0.69 0.08
263_V 52_L 0.69 0.08
282_L 47_T 0.69 0.08
259_V 164_F 0.69 0.08
242_G 176_W 0.69 0.08
241_N 132_A 0.69 0.08
157_D 109_A 0.68 0.08
82_P 41_I 0.68 0.08
231_A 176_W 0.67 0.08
200_L 184_A 0.67 0.08
119_R 204_Q 0.67 0.08
267_D 38_V 0.67 0.08
113_R 169_P 0.67 0.08
125_T 190_N 0.67 0.07
151_P 38_V 0.66 0.07
79_D 105_G 0.66 0.07
7_L 69_R 0.66 0.07
186_D 40_D 0.66 0.07
51_E 81_G 0.66 0.07
154_E 50_V 0.66 0.07
206_D 115_H 0.66 0.07
76_T 4_T 0.66 0.07
260_I 57_Y 0.66 0.07
31_S 46_R 0.66 0.07
90_G 98_H 0.66 0.07
261_G 8_Y 0.66 0.07
51_E 78_Q 0.66 0.07
150_L 48_V 0.66 0.07
225_Q 146_R 0.66 0.07
137_S 124_F 0.65 0.07
247_L 125_C 0.65 0.07
52_S 178_L 0.65 0.07
242_G 145_R 0.65 0.07
231_A 145_R 0.65 0.07
247_L 160_L 0.65 0.07
225_Q 136_D 0.65 0.07
233_R 12_A 0.65 0.07
38_S 60_P 0.65 0.07
262_V 9_G 0.65 0.07
253_V 129_P 0.65 0.07
24_A 124_F 0.65 0.07
184_R 45_A 0.65 0.07
207_R 130_G 0.65 0.07
103_I 41_I 0.65 0.07
232_T 8_Y 0.65 0.07
54_T 178_L 0.64 0.07
25_H 27_T 0.64 0.07
150_L 33_A 0.64 0.07
53_A 36_L 0.64 0.07
126_P 98_H 0.64 0.07
59_F 157_A 0.64 0.07
208_V 160_L 0.64 0.07
251_H 161_A 0.64 0.07
203_N 185_V 0.64 0.06
120_G 154_P 0.64 0.06
184_R 8_Y 0.64 0.06
9_T 141_L 0.64 0.06
245_V 149_P 0.64 0.06
165_A 205_F 0.64 0.06
253_V 125_C 0.64 0.06
240_P 46_R 0.63 0.06
257_Y 176_W 0.63 0.06
132_S 209_G 0.63 0.06
199_W 24_L 0.63 0.06
183_P 46_R 0.63 0.06
179_V 102_S 0.63 0.06
167_V 13_L 0.63 0.06
233_R 51_K 0.63 0.06
173_D 66_G 0.63 0.06
214_G 159_A 0.63 0.06
200_L 172_S 0.63 0.06
283_H 102_S 0.63 0.06
25_H 186_M 0.63 0.06
236_I 27_T 0.63 0.06
247_L 154_P 0.63 0.06
134_D 161_A 0.62 0.06
28_V 42_V 0.62 0.06
14_L 179_I 0.62 0.06
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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