May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

3IP4_B - 3IP4_C
PDB: 3IP4 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 575
Sequences: 689
Seq/Len: 1.21
I_Prob: 1.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
53_K 65_E 3.67 1.00
24_P 69_I 2.04 0.94
18_D 67_K 1.84 0.89
42_L 77_A 1.46 0.66
35_S 74_Q 1.26 0.45
137_S 94_I 1.23 0.42
82_F 16_A 1.22 0.42
24_P 68_A 1.19 0.38
59_A 68_A 1.10 0.29
197_L 95_M 1.05 0.24
19_S 68_A 1.04 0.24
276_V 61_N 1.02 0.22
26_P 68_A 1.00 0.20
19_S 5_T 0.98 0.19
284_W 65_E 0.96 0.17
105_I 9_V 0.95 0.17
32_E 74_Q 0.94 0.16
13_V 51_E 0.91 0.14
268_R 15_L 0.91 0.14
66_L 32_L 0.89 0.13
35_S 87_G 0.88 0.12
424_E 23_E 0.88 0.12
138_L 88_Q 0.87 0.12
274_D 15_L 0.86 0.11
276_V 58_D 0.86 0.11
134_G 94_I 0.85 0.11
42_L 89_F 0.85 0.11
115_R 8_E 0.85 0.11
136_Y 83_E 0.83 0.10
349_N 16_A 0.82 0.09
93_S 89_F 0.82 0.09
269_Y 15_L 0.81 0.09
39_V 77_A 0.81 0.09
51_V 61_N 0.81 0.09
131_T 88_Q 0.80 0.08
26_P 70_K 0.80 0.08
279_Y 60_Q 0.80 0.08
25_S 70_K 0.80 0.08
32_E 87_G 0.79 0.08
23_S 70_K 0.79 0.08
24_P 36_L 0.78 0.07
290_Q 65_E 0.77 0.07
290_Q 79_K 0.77 0.07
262_E 18_L 0.77 0.07
18_D 68_A 0.77 0.07
82_F 14_N 0.77 0.07
406_D 45_A 0.77 0.07
379_G 17_R 0.76 0.07
223_G 53_T 0.76 0.07
286_E 67_K 0.75 0.07
99_I 21_S 0.75 0.06
332_E 26_E 0.74 0.06
109_V 56_V 0.74 0.06
130_S 94_I 0.74 0.06
115_R 40_K 0.73 0.06
24_P 64_R 0.73 0.06
272_E 7_E 0.73 0.06
436_Y 46_D 0.72 0.06
422_V 34_S 0.72 0.05
425_A 5_T 0.72 0.05
195_I 18_L 0.71 0.05
63_A 88_Q 0.71 0.05
128_G 15_L 0.71 0.05
53_K 25_T 0.71 0.05
275_I 82_K 0.71 0.05
309_L 46_D 0.69 0.05
310_P 85_E 0.69 0.05
260_V 93_T 0.69 0.05
224_L 9_V 0.69 0.05
120_R 40_K 0.69 0.05
360_L 20_I 0.68 0.04
24_P 70_K 0.68 0.04
135_E 85_E 0.68 0.04
301_A 67_K 0.68 0.04
4_E 32_L 0.68 0.04
272_E 67_K 0.68 0.04
214_L 39_A 0.67 0.04
283_A 19_Q 0.67 0.04
270_F 15_L 0.67 0.04
69_E 16_A 0.67 0.04
37_T 77_A 0.67 0.04
105_I 86_D 0.67 0.04
437_K 27_E 0.66 0.04
25_S 69_I 0.66 0.04
161_K 30_N 0.66 0.04
115_R 18_L 0.66 0.04
278_L 33_E 0.66 0.04
19_S 73_P 0.66 0.04
402_Q 21_S 0.66 0.04
237_N 33_E 0.66 0.04
424_E 37_D 0.66 0.04
188_S 18_L 0.65 0.04
257_L 5_T 0.65 0.04
367_E 76_L 0.65 0.04
286_E 8_E 0.65 0.04
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

Page generated in 0.4097 seconds.