| Pen-1 |
| ID: | 1678814489 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 870 (814) | ||
| Sequences: | 8079 (6690.4) | ||
| Seq/Len: | 9.925 | ||
| Nf(neff/√len): | 234.5 |
HHblits Results: (2016_02)
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 344_T | 361_L | 4.580 | 1.00 |
| 533_L | 583_V | 4.128 | 1.00 |
| 249_A | 275_V | 3.835 | 1.00 |
| 622_Y | 680_I | 3.754 | 1.00 |
| 277_M | 286_L | 3.575 | 1.00 |
| 363_S | 542_D | 3.437 | 1.00 |
| 247_G | 343_S | 3.432 | 1.00 |
| 247_G | 542_D | 3.393 | 1.00 |
| 292_E | 349_F | 2.912 | 1.00 |
| 588_D | 592_S | 2.867 | 1.00 |
| 204_S | 229_E | 2.757 | 1.00 |
| 791_Q | 794_D | 2.663 | 1.00 |
| 584_R | 594_V | 2.632 | 1.00 |
| 229_E | 269_K | 2.562 | 1.00 |
| 536_E | 576_L | 2.537 | 1.00 |
| 749_L | 779_L | 2.535 | 1.00 |
| 530_V | 596_I | 2.522 | 1.00 |
| 251_P | 295_A | 2.498 | 1.00 |
| 50_L | 158_L | 2.487 | 1.00 |
| 233_T | 269_K | 2.465 | 1.00 |
| 60_D | 73_G | 2.449 | 1.00 |
| 238_H | 242_L | 2.425 | 1.00 |
| 385_R | 410_C | 2.401 | 1.00 |
| 226_R | 230_E | 2.398 | 1.00 |
| 746_L | 783_A | 2.346 | 1.00 |
| 235_L | 266_A | 2.341 | 1.00 |
| 248_K | 272_G | 2.325 | 1.00 |
| 763_N | 802_E | 2.314 | 1.00 |
| 476_K | 494_N | 2.293 | 1.00 |
| 235_L | 262_V | 2.251 | 1.00 |
| 143_A | 146_P | 2.241 | 1.00 |
| 81_E | 84_G | 2.226 | 1.00 |
| 206_K | 210_Q | 2.214 | 1.00 |
| 547_N | 550_K | 2.178 | 1.00 |
| 366_N | 540_V | 2.165 | 1.00 |
| 244_L | 272_G | 2.155 | 1.00 |
| 197_Q | 205_E | 2.155 | 1.00 |
| 246_T | 343_S | 2.147 | 1.00 |
| 752_K | 782_A | 2.145 | 1.00 |
| 765_H | 768_S | 2.143 | 1.00 |
| 800_I | 803_S | 2.131 | 1.00 |
| 647_V | 694_Y | 2.130 | 1.00 |
| 858_L | 861_A | 2.111 | 1.00 |
| 347_I | 545_L | 2.110 | 1.00 |
| 742_M | 809_K | 2.095 | 1.00 |
| 206_K | 209_S | 2.094 | 1.00 |
| 144_T | 148_E | 2.087 | 1.00 |
| 762_V | 801_L | 2.071 | 1.00 |
| 248_K | 296_G | 2.061 | 1.00 |
| 366_N | 487_T | 2.055 | 1.00 |
| 363_S | 366_N | 2.054 | 1.00 |
| 515_V | 593_V | 2.036 | 1.00 |
| 515_V | 583_V | 2.036 | 1.00 |
| 650_A | 700_M | 2.014 | 1.00 |
| 765_H | 799_P | 2.011 | 1.00 |
| 344_T | 542_D | 2.008 | 1.00 |
| 249_A | 347_I | 2.003 | 1.00 |
| 210_Q | 213_R | 1.989 | 1.00 |
| 736_I | 763_N | 1.985 | 1.00 |
| 739_R | 762_V | 1.953 | 1.00 |
| 425_G | 429_K | 1.938 | 1.00 |
| 229_E | 334_V | 1.928 | 1.00 |
| 436_H | 489_G | 1.923 | 1.00 |
| 233_T | 237_R | 1.923 | 1.00 |
| 260_T | 392_Y | 1.913 | 1.00 |
| 516_V | 534_L | 1.912 | 1.00 |
| 750_W | 801_L | 1.904 | 1.00 |
| 741_E | 744_R | 1.904 | 1.00 |
| 603_V | 612_L | 1.893 | 1.00 |
| 47_W | 108_L | 1.892 | 1.00 |
| 91_L | 95_R | 1.872 | 1.00 |
| 385_R | 432_V | 1.858 | 1.00 |
| 384_S | 433_N | 1.839 | 1.00 |
| 73_G | 81_E | 1.834 | 1.00 |
| 648_F | 714_R | 1.828 | 1.00 |
| 245_Q | 248_K | 1.823 | 1.00 |
| 558_D | 574_G | 1.823 | 1.00 |
| 223_M | 262_V | 1.810 | 1.00 |
| 649_V | 694_Y | 1.797 | 1.00 |
| 288_T | 356_K | 1.782 | 1.00 |
| 618_H | 681_L | 1.771 | 1.00 |
| 212_D | 226_R | 1.771 | 1.00 |
| 399_D | 489_G | 1.767 | 1.00 |
| 749_L | 783_A | 1.767 | 1.00 |
| 263_G | 267_V | 1.741 | 1.00 |
| 384_S | 409_G | 1.733 | 1.00 |
| 440_S | 461_E | 1.727 | 1.00 |
| 54_G | 153_H | 1.726 | 1.00 |
| 753_L | 779_L | 1.717 | 1.00 |
| 514_W | 517_D | 1.683 | 1.00 |
| 396_V | 436_H | 1.673 | 1.00 |
| 252_L | 263_G | 1.671 | 1.00 |
| 169_S | 172_E | 1.666 | 1.00 |
| 384_S | 454_E | 1.665 | 1.00 |
| 556_I | 576_L | 1.659 | 1.00 |
| 91_L | 94_I | 1.657 | 1.00 |
| 244_L | 248_K | 1.652 | 1.00 |
| 794_D | 807_K | 1.651 | 1.00 |
| 204_S | 232_S | 1.647 | 1.00 |
| 746_L | 801_L | 1.646 | 1.00 |
| 530_V | 582_L | 1.645 | 1.00 |
| 229_E | 233_T | 1.643 | 1.00 |
| 766_F | 771_G | 1.643 | 1.00 |
| 740_T | 762_V | 1.642 | 1.00 |
| 199_I | 367_Y | 1.632 | 1.00 |
| 55_T | 58_N | 1.630 | 1.00 |
| 266_A | 270_A | 1.622 | 1.00 |
| 48_V | 63_F | 1.619 | 1.00 |
| 231_R | 259_W | 1.616 | 1.00 |
| 214_P | 222_E | 1.610 | 1.00 |
| 161_S | 174_V | 1.601 | 1.00 |
| 480_A | 489_G | 1.598 | 1.00 |
| 761_G | 764_D | 1.590 | 1.00 |
| 586_D | 592_S | 1.590 | 1.00 |
| 290_A | 295_A | 1.584 | 1.00 |
| 746_L | 805_A | 1.580 | 1.00 |
| 778_R | 782_A | 1.577 | 1.00 |
| 249_A | 273_A | 1.576 | 1.00 |
| 389_F | 438_T | 1.576 | 1.00 |
| 342_S | 365_S | 1.576 | 1.00 |
| 415_S | 418_Q | 1.571 | 1.00 |
| 232_S | 269_K | 1.570 | 1.00 |
| 395_D | 483_P | 1.565 | 1.00 |
| 342_S | 363_S | 1.555 | 1.00 |
| 75_S | 80_I | 1.554 | 1.00 |
| 740_T | 744_R | 1.553 | 1.00 |
| 493_N | 504_S | 1.551 | 1.00 |
| 125_A | 134_V | 1.551 | 1.00 |
| 605_L | 610_V | 1.548 | 1.00 |
| 861_A | 865_L | 1.547 | 1.00 |
| 697_L | 700_M | 1.545 | 1.00 |
| 793_T | 797_Q | 1.543 | 1.00 |
| 740_T | 809_K | 1.541 | 1.00 |
| 72_Q | 81_E | 1.534 | 1.00 |
| 205_E | 209_S | 1.533 | 1.00 |
| 229_E | 232_S | 1.532 | 1.00 |
| 491_T | 513_T | 1.530 | 1.00 |
| 412_C | 432_V | 1.529 | 1.00 |
| 400_C | 436_H | 1.525 | 1.00 |
| 136_G | 147_V | 1.518 | 1.00 |
| 412_C | 426_A | 1.517 | 1.00 |
| 399_D | 436_H | 1.515 | 1.00 |
| 237_R | 335_D | 1.515 | 1.00 |
| 252_L | 264_V | 1.511 | 1.00 |
| 774_L | 777_M | 1.511 | 1.00 |
| 200_Q | 364_H | 1.510 | 1.00 |
| 340_P | 343_S | 1.508 | 1.00 |
| 426_A | 430_L | 1.503 | 1.00 |
| 375_A | 407_N | 1.493 | 1.00 |
| 779_L | 795_I | 1.489 | 1.00 |
| 292_E | 547_N | 1.485 | 1.00 |
| 743_E | 762_V | 1.485 | 1.00 |
| 73_G | 84_G | 1.477 | 1.00 |
| 136_G | 151_L | 1.476 | 1.00 |
| 390_P | 396_V | 1.472 | 1.00 |
| 436_H | 480_A | 1.472 | 1.00 |
| 321_G | 324_N | 1.471 | 1.00 |
| 621_N | 684_N | 1.470 | 1.00 |
| 416_E | 419_R | 1.466 | 1.00 |
| 649_V | 696_P | 1.457 | 1.00 |
| 798_S | 807_K | 1.452 | 1.00 |
| 254_F | 263_G | 1.451 | 1.00 |
| 268_M | 345_L | 1.447 | 1.00 |
| 204_S | 269_K | 1.446 | 1.00 |
| 648_F | 716_L | 1.446 | 1.00 |
| 301_S | 304_Q | 1.445 | 1.00 |
| 261_I | 401_M | 1.438 | 1.00 |
| 214_P | 410_C | 1.437 | 1.00 |
| 736_I | 762_V | 1.437 | 1.00 |
| 369_S | 511_G | 1.435 | 1.00 |
| 784_R | 789_A | 1.433 | 1.00 |
| 783_A | 788_L | 1.431 | 1.00 |
| 586_D | 594_V | 1.431 | 1.00 |
| 143_A | 147_V | 1.422 | 1.00 |
| 223_M | 258_M | 1.422 | 1.00 |
| 515_V | 518_P | 1.421 | 1.00 |
| 198_C | 201_D | 1.419 | 1.00 |
| 370_G | 489_G | 1.417 | 1.00 |
| 360_V | 541_G | 1.411 | 1.00 |
| 287_S | 291_S | 1.407 | 0.99 |
| 99_Q | 102_G | 1.403 | 0.99 |
| 772_D | 775_K | 1.403 | 0.99 |
| 165_N | 168_Q | 1.398 | 0.99 |
| 513_T | 535_I | 1.397 | 0.99 |
| 436_H | 439_P | 1.397 | 0.99 |
| 200_Q | 339_V | 1.397 | 0.99 |
| 404_T | 411_I | 1.397 | 0.99 |
| 73_G | 79_V | 1.396 | 0.99 |
| 646_I | 695_I | 1.394 | 0.99 |
| 735_K | 759_D | 1.393 | 0.99 |
| 490_C | 535_I | 1.387 | 0.99 |
| 44_A | 48_V | 1.385 | 0.99 |
| 742_M | 745_K | 1.383 | 0.99 |
| 73_G | 80_I | 1.380 | 0.99 |
| 739_R | 743_E | 1.375 | 0.99 |
| 376_E | 510_G | 1.368 | 0.99 |
| 339_V | 343_S | 1.368 | 0.99 |
| 370_G | 399_D | 1.365 | 0.99 |
| 39_H | 132_V | 1.365 | 0.99 |
| 629_V | 708_T | 1.365 | 0.99 |
| 532_E | 578_K | 1.364 | 0.99 |
| 618_H | 621_N | 1.363 | 0.99 |
| 90_A | 95_R | 1.363 | 0.99 |
| 214_P | 224_T | 1.361 | 0.99 |
| 81_E | 85_S | 1.361 | 0.99 |
| 767_F | 796_F | 1.360 | 0.99 |
| 772_D | 777_M | 1.358 | 0.99 |
| 174_V | 181_L | 1.358 | 0.99 |
| 550_K | 554_V | 1.355 | 0.99 |
| 522_D | 534_L | 1.354 | 0.99 |
| 601_Q | 710_R | 1.352 | 0.99 |
| 281_Q | 289_I | 1.351 | 0.99 |
| 244_L | 250_V | 1.349 | 0.99 |
| 558_D | 576_L | 1.343 | 0.99 |
| 291_S | 356_K | 1.342 | 0.99 |
| 517_D | 523_R | 1.341 | 0.99 |
| 218_S | 258_M | 1.335 | 0.99 |
| 47_W | 110_F | 1.335 | 0.99 |
| 187_W | 585_Y | 1.331 | 0.99 |
| 247_G | 344_T | 1.330 | 0.99 |
| 745_K | 748_G | 1.330 | 0.99 |
| 678_D | 694_Y | 1.328 | 0.99 |
| 457_G | 480_A | 1.327 | 0.99 |
| 32_P | 42_I | 1.326 | 0.99 |
| 44_A | 63_F | 1.322 | 0.99 |
| 123_L | 136_G | 1.321 | 0.99 |
| 436_H | 459_G | 1.319 | 0.99 |
| 387_L | 427_I | 1.315 | 0.99 |
| 217_V | 430_L | 1.314 | 0.99 |
| 110_F | 155_L | 1.314 | 0.99 |
| 202_I | 368_T | 1.311 | 0.99 |
| 64_S | 106_D | 1.305 | 0.99 |
| 776_A | 792_V | 1.303 | 0.99 |
| 548_P | 552_A | 1.303 | 0.99 |
| 48_V | 74_G | 1.302 | 0.99 |
| 111_R | 114_S | 1.300 | 0.99 |
| 390_P | 436_H | 1.297 | 0.99 |
| 389_F | 437_M | 1.297 | 0.99 |
| 362_I | 541_G | 1.293 | 0.99 |
| 47_W | 123_L | 1.284 | 0.99 |
| 77_S | 80_I | 1.284 | 0.99 |
| 217_V | 410_C | 1.283 | 0.99 |
| 399_D | 480_A | 1.280 | 0.99 |
| 629_V | 700_M | 1.280 | 0.99 |
| 396_V | 489_G | 1.280 | 0.99 |
| 414_P | 426_A | 1.279 | 0.99 |
| 788_L | 808_V | 1.278 | 0.99 |
| 493_N | 592_S | 1.274 | 0.99 |
| 80_I | 85_S | 1.274 | 0.99 |
| 89_S | 92_E | 1.273 | 0.99 |
| 203_I | 207_A | 1.271 | 0.99 |
| 435_A | 453_L | 1.267 | 0.99 |
| 619_V | 647_V | 1.265 | 0.99 |
| 158_L | 173_A | 1.264 | 0.99 |
| 772_D | 776_A | 1.262 | 0.99 |
| 443_R | 467_D | 1.256 | 0.99 |
| 400_C | 489_G | 1.255 | 0.99 |
| 514_W | 518_P | 1.254 | 0.99 |
| 385_R | 412_C | 1.254 | 0.99 |
| 255_E | 301_S | 1.252 | 0.99 |
| 616_E | 630_A | 1.251 | 0.99 |
| 283_E | 287_S | 1.246 | 0.98 |
| 774_L | 792_V | 1.245 | 0.98 |
| 747_H | 801_L | 1.244 | 0.98 |
| 263_G | 299_L | 1.243 | 0.98 |
| 216_V | 261_I | 1.243 | 0.98 |
| 146_P | 149_S | 1.240 | 0.98 |
| 52_F | 55_T | 1.239 | 0.98 |
| 776_A | 780_V | 1.237 | 0.98 |
| 459_G | 489_G | 1.237 | 0.98 |
| 772_D | 783_A | 1.236 | 0.98 |
| 370_G | 400_C | 1.233 | 0.98 |
| 95_R | 98_G | 1.232 | 0.98 |
| 486_C | 535_I | 1.226 | 0.98 |
| 371_A | 406_A | 1.225 | 0.98 |
| 156_A | 160_L | 1.224 | 0.98 |
| 288_T | 349_F | 1.220 | 0.98 |
| 204_S | 233_T | 1.220 | 0.98 |
| 79_V | 83_E | 1.219 | 0.98 |
| 389_F | 489_G | 1.219 | 0.98 |
| 515_V | 519_S | 1.219 | 0.98 |
| 292_E | 356_K | 1.216 | 0.98 |
| 46_A | 159_I | 1.214 | 0.98 |
| 618_H | 684_N | 1.213 | 0.98 |
| 396_V | 399_D | 1.213 | 0.98 |
| 856_T | 861_A | 1.211 | 0.98 |
| 745_K | 786_Q | 1.210 | 0.98 |
| 153_H | 180_E | 1.209 | 0.98 |
| 37_I | 41_E | 1.209 | 0.98 |
| 74_G | 81_E | 1.208 | 0.98 |
| 858_L | 865_L | 1.207 | 0.98 |
| 201_D | 204_S | 1.207 | 0.98 |
| 404_T | 409_G | 1.204 | 0.98 |
| 486_C | 490_C | 1.203 | 0.98 |
| 216_V | 258_M | 1.202 | 0.98 |
| 90_A | 94_I | 1.202 | 0.98 |
| 534_L | 578_K | 1.201 | 0.98 |
| 582_L | 599_A | 1.198 | 0.98 |
| 739_R | 802_E | 1.197 | 0.98 |
| 858_L | 863_M | 1.195 | 0.98 |
| 281_Q | 393_A | 1.192 | 0.98 |
| 762_V | 802_E | 1.192 | 0.98 |
| 442_A | 458_L | 1.189 | 0.98 |
| 90_A | 93_A | 1.188 | 0.98 |
| 857_P | 861_A | 1.187 | 0.98 |
| 743_E | 805_A | 1.186 | 0.98 |
| 214_P | 217_V | 1.185 | 0.98 |
| 396_V | 459_G | 1.182 | 0.98 |
| 400_C | 480_A | 1.182 | 0.98 |
| 422_D | 425_G | 1.181 | 0.98 |
| 218_S | 221_G | 1.181 | 0.98 |
| 777_M | 792_V | 1.180 | 0.98 |
| 388_D | 400_C | 1.176 | 0.98 |
| 76_I | 80_I | 1.176 | 0.98 |
| 772_D | 792_V | 1.175 | 0.98 |
| 794_D | 797_Q | 1.175 | 0.98 |
| 264_V | 401_M | 1.174 | 0.98 |
| 273_A | 344_T | 1.172 | 0.97 |
| 259_W | 301_S | 1.171 | 0.97 |
| 300_T | 304_Q | 1.171 | 0.97 |
| 387_L | 414_P | 1.170 | 0.97 |
| 857_P | 863_M | 1.170 | 0.97 |
| 747_H | 762_V | 1.169 | 0.97 |
| 486_C | 540_V | 1.169 | 0.97 |
| 389_F | 441_V | 1.161 | 0.97 |
| 231_R | 234_N | 1.157 | 0.97 |
| 275_V | 293_V | 1.157 | 0.97 |
| 507_Q | 592_S | 1.155 | 0.97 |
| 43_I | 110_F | 1.153 | 0.97 |
| 608_Q | 688_Y | 1.152 | 0.97 |
| 117_N | 120_T | 1.152 | 0.97 |
| 583_V | 593_V | 1.150 | 0.97 |
| 861_A | 864_A | 1.146 | 0.97 |
| 735_K | 761_G | 1.146 | 0.97 |
| 436_H | 441_V | 1.145 | 0.97 |
| 370_G | 459_G | 1.144 | 0.97 |
| 40_E | 44_A | 1.138 | 0.97 |
| 371_A | 403_C | 1.137 | 0.97 |
| 80_I | 84_G | 1.137 | 0.97 |
| 155_L | 159_I | 1.137 | 0.97 |
| 776_A | 795_I | 1.132 | 0.97 |
| 72_Q | 84_G | 1.131 | 0.97 |
| 187_W | 527_I | 1.128 | 0.97 |
| 370_G | 436_H | 1.127 | 0.97 |
| 855_C | 859_Q | 1.127 | 0.97 |
| 370_G | 487_T | 1.127 | 0.97 |
| 388_D | 413_V | 1.126 | 0.97 |
| 605_L | 634_I | 1.123 | 0.97 |
| 464_S | 467_D | 1.122 | 0.96 |
| 384_S | 434_M | 1.120 | 0.96 |
| 75_S | 79_V | 1.118 | 0.96 |
| 396_V | 480_A | 1.116 | 0.96 |
| 168_Q | 172_E | 1.116 | 0.96 |
| 346_Y | 362_I | 1.113 | 0.96 |
| 409_G | 433_N | 1.112 | 0.96 |
| 75_S | 81_E | 1.110 | 0.96 |
| 374_R | 399_D | 1.103 | 0.96 |
| 465_A | 469_A | 1.103 | 0.96 |
| 862_L | 865_L | 1.101 | 0.96 |
| 79_V | 84_G | 1.094 | 0.96 |
| 418_Q | 422_D | 1.093 | 0.96 |
| 202_I | 372_L | 1.093 | 0.96 |
| 709_D | 712_Q | 1.090 | 0.96 |
| 197_Q | 201_D | 1.090 | 0.96 |
| 367_Y | 488_V | 1.089 | 0.96 |
| 779_L | 804_L | 1.089 | 0.96 |
| 463_I | 479_I | 1.086 | 0.96 |
| 853_Y | 861_A | 1.086 | 0.96 |
| 700_M | 708_T | 1.082 | 0.95 |
| 72_Q | 79_V | 1.081 | 0.95 |
| 747_H | 760_I | 1.078 | 0.95 |
| 673_L | 676_G | 1.077 | 0.95 |
| 47_W | 63_F | 1.077 | 0.95 |
| 744_R | 748_G | 1.077 | 0.95 |
| 281_Q | 688_Y | 1.077 | 0.95 |
| 513_T | 583_V | 1.076 | 0.95 |
| 44_A | 110_F | 1.076 | 0.95 |
| 748_G | 786_Q | 1.075 | 0.95 |
| 73_G | 83_E | 1.074 | 0.95 |
| 288_T | 292_E | 1.072 | 0.95 |
| 251_P | 290_A | 1.072 | 0.95 |
| 274_L | 398_V | 1.071 | 0.95 |
| 783_A | 790_I | 1.071 | 0.95 |
| 380_Y | 409_G | 1.070 | 0.95 |
| 203_I | 265_L | 1.069 | 0.95 |
| 386_V | 404_T | 1.066 | 0.95 |
| 254_F | 299_L | 1.066 | 0.95 |
| 780_V | 795_I | 1.065 | 0.95 |
| 72_Q | 75_S | 1.061 | 0.95 |
| 856_T | 859_Q | 1.061 | 0.95 |
| 50_L | 54_G | 1.061 | 0.95 |
| 541_G | 555_F | 1.060 | 0.95 |
| 77_S | 81_E | 1.059 | 0.95 |
| 49_L | 158_L | 1.053 | 0.94 |
| 320_V | 324_N | 1.052 | 0.94 |
| 43_I | 132_V | 1.051 | 0.94 |
| 515_V | 533_L | 1.049 | 0.94 |
| 526_P | 529_T | 1.047 | 0.94 |
| 375_A | 403_C | 1.046 | 0.94 |
| 439_P | 442_A | 1.044 | 0.94 |
| 293_V | 349_F | 1.043 | 0.94 |
| 381_K | 384_S | 1.042 | 0.94 |
| 736_I | 802_E | 1.038 | 0.94 |
| 431_N | 452_S | 1.038 | 0.94 |
| 560_T | 565_G | 1.036 | 0.94 |
| 362_I | 487_T | 1.035 | 0.94 |
| 172_E | 523_R | 1.033 | 0.94 |
| 102_G | 107_T | 1.032 | 0.94 |
| 651_E | 696_P | 1.030 | 0.94 |
| 72_Q | 83_E | 1.028 | 0.94 |
| 534_L | 556_I | 1.027 | 0.93 |
| 399_D | 441_V | 1.026 | 0.93 |
| 751_L | 760_I | 1.026 | 0.93 |
| 455_V | 476_K | 1.026 | 0.93 |
| 527_I | 585_Y | 1.023 | 0.93 |
| 459_G | 487_T | 1.022 | 0.93 |
| 513_T | 533_L | 1.022 | 0.93 |
| 224_T | 227_Q | 1.022 | 0.93 |
| 182_S | 186_K | 1.019 | 0.93 |
| 680_I | 684_N | 1.018 | 0.93 |
| 742_M | 808_V | 1.017 | 0.93 |
| 370_G | 490_C | 1.013 | 0.93 |
| 92_E | 95_R | 1.012 | 0.93 |
| 397_S | 401_M | 1.011 | 0.93 |
| 442_A | 456_I | 1.011 | 0.93 |
| 605_L | 643_A | 1.007 | 0.93 |
| 40_E | 63_F | 1.006 | 0.93 |
| 513_T | 517_D | 1.005 | 0.93 |
| 80_I | 83_E | 1.005 | 0.93 |
| 801_L | 804_L | 1.000 | 0.92 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 2vsqA | 1 | 0.9126 | 100 | 0.269 | Contact Map |
| 4dg8A | 1 | 0.5563 | 100 | 0.402 | Contact Map |
| 4iz6A | 2 | 0.6701 | 100 | 0.423 | Contact Map |
| 4r0mB | 2 | 0.6701 | 100 | 0.443 | Contact Map |
| 1amuA | 2 | 0.5793 | 100 | 0.484 | Contact Map |
| 4d4iA | 1 | 0 | 100 | 0.505 | Contact Map |
| 3g7sA | 2 | 0.5356 | 100 | 0.527 | Contact Map |
| 3tsyA | 1 | 0.5931 | 100 | 0.529 | Contact Map |
| 3vnrA | 1 | 0.5471 | 100 | 0.534 | Contact Map |
| 3wvnA | 2 | 0.4264 | 100 | 0.536 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)