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OPENSEQ.org

YFIP - DTW domain-containing protein YfiP
UniProt: Q47319 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14223
Length: 232 (223)
Sequences: 420
Seq/Len: 1.88

YFIP
Paralog alert: 0.20 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
133_F 189_L 2.544 1.00
168_A 207_T 2.318 1.00
108_V 134_I 2.109 0.99
106_P 132_L 2.061 0.99
31_C 34_C 1.939 0.98
75_A 81_T 1.801 0.97
171_L 181_C 1.722 0.96
16_R 22_L 1.7 0.96
12_E 16_R 1.691 0.95
93_Q 97_E 1.674 0.95
136_L 146_M 1.671 0.95
59_M 71_G 1.619 0.94
187_I 206_F 1.608 0.94
110_F 171_L 1.602 0.93
142_E 149_K 1.598 0.93
70_T 210_K 1.545 0.92
71_G 83_A 1.52 0.91
161_V 189_L 1.496 0.90
74_I 186_A 1.465 0.89
174_A 179_Q 1.456 0.88
16_R 26_N 1.43 0.87
4_N 7_L 1.411 0.86
118_Q 159_I 1.394 0.85
132_L 142_E 1.372 0.84
54_R 82_V 1.363 0.83
74_I 77_I 1.351 0.83
88_R 150_S 1.351 0.83
110_F 132_L 1.348 0.82
138_G 159_I 1.348 0.82
56_C 132_L 1.337 0.82
146_M 150_S 1.329 0.81
12_E 15_A 1.328 0.81
142_E 145_K 1.315 0.80
205_H 209_F 1.304 0.79
11_A 18_T 1.301 0.79
11_A 26_N 1.294 0.79
10_R 139_T 1.286 0.78
86_W 89_T 1.286 0.78
22_L 26_N 1.284 0.78
70_T 189_L 1.271 0.77
15_A 61_D 1.267 0.77
89_T 152_Y 1.266 0.77
195_D 198_A 1.243 0.75
57_L 71_G 1.219 0.73
108_V 156_L 1.216 0.72
146_M 153_L 1.216 0.72
29_R 38_E 1.214 0.72
101_N 129_K 1.212 0.72
108_V 158_V 1.208 0.72
87_S 142_E 1.201 0.71
68_S 205_H 1.194 0.70
16_R 21_F 1.175 0.69
141_P 173_E 1.175 0.69
18_T 22_L 1.174 0.69
87_S 149_K 1.174 0.69
70_T 192_M 1.162 0.67
88_R 152_Y 1.162 0.67
14_I 21_F 1.157 0.67
169_Y 172_R 1.155 0.67
171_L 178_G 1.153 0.67
72_R 138_G 1.152 0.67
95_L 150_S 1.144 0.66
179_Q 209_F 1.144 0.66
11_A 17_A 1.143 0.66
135_M 186_A 1.14 0.65
96_L 134_I 1.14 0.65
44_S 52_K 1.14 0.65
77_I 187_I 1.136 0.65
50_Q 200_A 1.134 0.65
136_L 186_A 1.125 0.64
16_R 222_G 1.118 0.63
210_K 217_K 1.118 0.63
44_S 134_I 1.117 0.63
5_A 8_Q 1.112 0.63
159_I 164_S 1.109 0.62
54_R 132_L 1.109 0.62
95_L 139_T 1.106 0.62
88_R 149_K 1.103 0.62
3_E 16_R 1.103 0.62
67_P 76_D 1.098 0.61
72_R 157_P 1.096 0.61
69_N 88_R 1.094 0.61
2_T 7_L 1.093 0.61
66_K 202_L 1.091 0.60
69_N 73_L 1.089 0.60
86_W 150_S 1.088 0.60
48_P 79_P 1.086 0.60
55_F 78_L 1.085 0.60
134_I 168_A 1.076 0.59
7_L 10_R 1.076 0.59
47_T 110_F 1.076 0.59
108_V 201_G 1.076 0.59
3_E 221_L 1.074 0.59
22_L 221_L 1.071 0.58
12_E 22_L 1.067 0.58
2_T 26_N 1.062 0.57
181_C 219_Q 1.061 0.57
88_R 209_F 1.055 0.56
145_K 149_K 1.054 0.56
7_L 180_Y 1.052 0.56
147_F 209_F 1.051 0.56
163_L 180_Y 1.048 0.56
13_R 20_P 1.047 0.56
8_Q 13_R 1.046 0.55
77_I 186_A 1.043 0.55
96_L 100_Q 1.04 0.55
36_L 72_R 1.039 0.55
19_R 223_S 1.038 0.55
147_F 158_V 1.037 0.55
5_A 20_P 1.034 0.54
109_V 193_A 1.033 0.54
103_D 129_K 1.028 0.54
70_T 213_Y 1.025 0.53
109_V 135_M 1.018 0.52
57_L 188_A 1.018 0.52
214_L 217_K 1.01 0.52
105_Q 129_K 1.004 0.51
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3p8bA20.32767.50.967Contact Map0.217
1l6nA10.396670.967Contact Map0.054
4jmuA10.37936.60.968Contact Map0.07
2golA10.37936.20.968Contact Map0.071
1ed1A10.3755.40.969Contact Map0.067
3j20Y10.17673.60.972Contact Map0.131
3h7hA10.40953.40.972Contact Map0.199
3sbxA80.65523.20.972Contact Map0.15
1rk8C10.253.20.972Contact Map0.17
1vk0A60.461230.973Contact Map0.083

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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