| UniProt: | Q47140 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13457 | ||
| Length: | 172 (167) | ||
| Sequences: | 585 | ||
| Seq/Len: | 3.50 |
| HCAF
Paralog alert: 0.28 [within 20: 0.07] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 28_K | 31_D | 5.311 | 1.00 | |
| 22_S | 103_Q | 3.661 | 1.00 | |
| 117_V | 139_D | 3.222 | 1.00 | |
| 38_E | 71_K | 3.1 | 1.00 | |
| 119_Y | 135_G | 3.07 | 1.00 | |
| 144_L | 148_N | 2.947 | 1.00 | |
| 30_R | 82_E | 2.601 | 1.00 | |
| 12_R | 143_R | 2.577 | 1.00 | |
| 142_R | 152_L | 2.217 | 1.00 | |
| 96_R | 159_D | 2.059 | 1.00 | |
| 91_P | 125_Q | 1.98 | 1.00 | |
| 23_L | 35_Q | 1.947 | 1.00 | |
| 16_F | 141_V | 1.889 | 1.00 | |
| 41_R | 153_E | 1.876 | 1.00 | |
| 13_I | 104_I | 1.818 | 0.99 | |
| 112_V | 142_R | 1.766 | 0.99 | |
| 143_R | 149_W | 1.741 | 0.99 | |
| 89_E | 93_S | 1.678 | 0.99 | |
| 17_L | 115_V | 1.608 | 0.98 | |
| 99_I | 102_C | 1.586 | 0.98 | |
| 43_T | 155_D | 1.562 | 0.98 | |
| 44_M | 156_I | 1.555 | 0.98 | |
| 141_V | 151_L | 1.534 | 0.97 | |
| 40_I | 74_L | 1.531 | 0.97 | |
| 36_L | 40_I | 1.489 | 0.97 | |
| 80_R | 86_A | 1.478 | 0.96 | |
| 117_V | 137_R | 1.453 | 0.96 | |
| 23_L | 31_D | 1.421 | 0.95 | |
| 37_D | 150_R | 1.407 | 0.95 | |
| 113_F | 149_W | 1.399 | 0.95 | |
| 31_D | 34_A | 1.364 | 0.94 | |
| 33_L | 74_L | 1.357 | 0.93 | |
| 108_D | 114_A | 1.345 | 0.93 | |
| 39_E | 152_L | 1.332 | 0.93 | |
| 17_L | 102_C | 1.306 | 0.92 | |
| 108_D | 112_V | 1.293 | 0.91 | |
| 71_K | 75_E | 1.289 | 0.91 | |
| 20_E | 32_W | 1.279 | 0.91 | |
| 101_N | 118_N | 1.274 | 0.90 | |
| 86_A | 95_T | 1.269 | 0.90 | |
| 122_Y | 134_V | 1.261 | 0.90 | |
| 108_D | 111_N | 1.26 | 0.90 | |
| 39_E | 142_R | 1.251 | 0.89 | |
| 76_R | 135_G | 1.228 | 0.88 | |
| 22_S | 116_R | 1.221 | 0.88 | |
| 36_L | 151_L | 1.207 | 0.87 | |
| 16_F | 151_L | 1.19 | 0.86 | |
| 19_H | 103_Q | 1.185 | 0.85 | |
| 18_F | 101_N | 1.18 | 0.85 | |
| 33_L | 75_E | 1.174 | 0.85 | |
| 89_E | 123_R | 1.165 | 0.84 | |
| 10_H | 15_Q | 1.162 | 0.84 | |
| 24_L | 95_T | 1.156 | 0.84 | |
| 116_R | 136_T | 1.155 | 0.83 | |
| 13_I | 141_V | 1.144 | 0.83 | |
| 76_R | 79_A | 1.13 | 0.82 | |
| 19_H | 23_L | 1.125 | 0.81 | |
| 22_S | 26_D | 1.123 | 0.81 | |
| 99_I | 114_A | 1.119 | 0.81 | |
| 99_I | 117_V | 1.118 | 0.81 | |
| 107_T | 143_R | 1.102 | 0.79 | |
| 37_D | 152_L | 1.102 | 0.79 | |
| 60_Q | 63_T | 1.094 | 0.79 | |
| 13_I | 113_F | 1.08 | 0.77 | |
| 122_Y | 132_F | 1.08 | 0.77 | |
| 34_A | 150_R | 1.071 | 0.77 | |
| 16_F | 112_V | 1.054 | 0.75 | |
| 37_D | 142_R | 1.042 | 0.74 | |
| 23_L | 28_K | 1.031 | 0.73 | |
| 102_C | 117_V | 1.015 | 0.71 | |
| 66_I | 73_Q | 1.009 | 0.70 | |
| 98_L | 120_L | 1.007 | 0.70 | |
| 139_D | 154_R | 1 | 0.69 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2bmoB | 1 | 0.9709 | 100 | 0.286 | Contact Map | 0.68 |
| 3gzxB | 1 | 0.9942 | 100 | 0.316 | Contact Map | 0.694 |
| 2gbwB | 3 | 0.9884 | 100 | 0.327 | Contact Map | 0.775 |
| 1wqlB | 1 | 0.9942 | 100 | 0.334 | Contact Map | 0.687 |
| 1uliB | 3 | 0.9942 | 100 | 0.343 | Contact Map | 0.871 |
| 2b1xB | 3 | 0.9709 | 100 | 0.362 | Contact Map | 0.816 |
| 3e99A | 1 | 0.9244 | 100 | 0.413 | Contact Map | 0.668 |
| 3ebyA | 1 | 0.9244 | 99.9 | 0.46 | Contact Map | 0.6 |
| 3ejvA | 1 | 0.8605 | 99.6 | 0.652 | Contact Map | 0.551 |
| 2rgqA | 3 | 0.8081 | 99.6 | 0.667 | Contact Map | 0.767 |
Sequence Conservation (Image Generated using WebLogo v3)