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OPENSEQ.org
YGCP - Uncharacterized protein YgcP
UniProt: Q46906 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13123
Length: 191 (185)
Sequences: 272
Seq/Len: 1.47
YGCP
Paralog alert: 0.11 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
67_A 73_V 2.579 1.00
50_I 57_A 2.37 1.00
144_W 160_C 2.141 0.99
25_A 33_I 1.841 0.96
162_E 166_R 1.698 0.93
33_I 50_I 1.679 0.93
47_V 108_L 1.669 0.92
98_R 129_D 1.667 0.92
63_L 134_L 1.546 0.88
168_A 173_V 1.544 0.88
86_I 162_E 1.521 0.87
14_A 30_C 1.502 0.86
47_V 57_A 1.491 0.85
51_K 84_D 1.466 0.84
40_I 44_S 1.457 0.83
75_Q 96_A 1.437 0.82
88_S 94_L 1.43 0.82
17_K 164_D 1.428 0.82
131_I 169_I 1.427 0.82
89_T 156_G 1.415 0.81
78_K 102_F 1.413 0.81
136_G 159_V 1.41 0.81
60_H 156_G 1.404 0.80
133_I 145_V 1.396 0.80
38_G 158_L 1.394 0.80
3_L 6_L 1.382 0.79
12_V 165_A 1.38 0.79
47_V 81_T 1.37 0.78
63_L 179_T 1.351 0.77
140_K 164_D 1.348 0.76
16_V 33_I 1.348 0.76
15_A 62_D 1.342 0.76
118_N 180_N 1.323 0.74
64_L 98_R 1.32 0.74
120_D 145_V 1.315 0.74
137_C 155_A 1.313 0.74
36_L 62_D 1.306 0.73
94_L 104_C 1.276 0.71
17_K 63_L 1.274 0.70
107_R 156_G 1.272 0.70
60_H 128_P 1.269 0.70
108_L 119_I 1.269 0.70
14_A 32_F 1.267 0.70
26_I 176_L 1.25 0.68
113_S 134_L 1.248 0.68
178_T 183_V 1.241 0.67
17_K 70_K 1.241 0.67
12_V 98_R 1.23 0.66
18_D 21_S 1.226 0.66
76_F 80_V 1.219 0.65
89_T 109_F 1.217 0.65
60_H 89_T 1.199 0.64
71_E 168_A 1.183 0.62
28_S 171_A 1.175 0.61
125_Q 175_A 1.165 0.60
43_I 76_F 1.163 0.60
15_A 36_L 1.156 0.59
156_G 159_V 1.15 0.59
68_S 118_N 1.148 0.59
85_G 107_R 1.141 0.58
78_K 177_S 1.138 0.58
17_K 138_M 1.134 0.57
44_S 80_V 1.133 0.57
106_H 159_V 1.122 0.56
21_S 181_T 1.118 0.56
48_K 82_E 1.115 0.55
43_I 86_I 1.113 0.55
46_I 58_F 1.112 0.55
52_N 169_I 1.11 0.55
21_S 113_S 1.101 0.54
31_Q 77_L 1.081 0.52
33_I 63_L 1.08 0.52
122_Q 134_L 1.074 0.51
144_W 147_E 1.073 0.51
16_V 50_I 1.07 0.51
4_L 7_L 1.069 0.51
46_I 179_T 1.059 0.50
121_K 174_V 1.053 0.49
52_N 64_L 1.052 0.49
22_L 50_I 1.051 0.49
87_I 134_L 1.05 0.49
139_P 142_L 1.042 0.48
17_K 25_A 1.04 0.48
30_C 39_N 1.035 0.47
25_A 116_F 1.03 0.47
107_R 132_E 1.029 0.46
142_L 171_A 1.029 0.46
36_L 134_L 1.026 0.46
43_I 51_K 1.023 0.46
58_F 154_I 1.022 0.46
15_A 115_S 1.022 0.46
51_K 167_N 1.019 0.45
14_A 134_L 1.019 0.45
39_N 72_V 1.008 0.44
19_N 37_Y 1.006 0.44
9_Q 176_L 1.002 0.44
90_K 95_K 1 0.44
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1vkfA40.93721000.167Contact Map0.346
3ktsA811000.352Contact Map0.429
1wa3A60.926798.70.838Contact Map0.246
4adtA20.937298.50.85Contact Map0.273
3labA20.926798.40.854Contact Map0.277
4axkA20.874398.30.858Contact Map0.194
1vhcA60.926798.20.861Contact Map0.297
2yw3A60.916298.10.866Contact Map0.268
4e38A30.926798.10.866Contact Map0.295
1geqA20.931998.10.867Contact Map0.285
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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