| UniProt: | Q46893 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13110 | ||
| Length: | 236 (223) | ||
| Sequences: | 1931 | ||
| Seq/Len: | 8.66 |
| ISPD
Paralog alert: 0.09 [within 20: 0.03] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 35_Q | 43_H | 3.757 | 1.00 | |
| 36_T | 39_E | 3.221 | 1.00 | |
| 104_V | 174_L | 3.204 | 1.00 | |
| 57_A | 92_G | 3.139 | 1.00 | |
| 84_E | 87_D | 2.964 | 1.00 | |
| 143_R | 153_H | 2.873 | 1.00 | |
| 134_A | 204_L | 2.775 | 1.00 | |
| 120_L | 168_F | 2.681 | 1.00 | |
| 144_A | 204_L | 2.574 | 1.00 | |
| 12_V | 45_L | 2.425 | 1.00 | |
| 113_H | 208_R | 2.222 | 1.00 | |
| 37_I | 214_V | 2.173 | 1.00 | |
| 173_L | 195_L | 2.173 | 1.00 | |
| 132_I | 192_A | 2.146 | 1.00 | |
| 103_L | 168_F | 2.131 | 1.00 | |
| 142_K | 196_E | 2.097 | 1.00 | |
| 21_M | 30_L | 2.027 | 1.00 | |
| 141_M | 162_H | 2.023 | 1.00 | |
| 154_T | 196_E | 1.981 | 1.00 | |
| 90_L | 94_K | 1.958 | 1.00 | |
| 48_H | 118_A | 1.867 | 1.00 | |
| 137_V | 160_L | 1.856 | 1.00 | |
| 60_P | 80_D | 1.846 | 1.00 | |
| 180_R | 184_E | 1.831 | 1.00 | |
| 57_A | 88_S | 1.817 | 1.00 | |
| 116_D | 133_L | 1.78 | 1.00 | |
| 142_K | 154_T | 1.76 | 1.00 | |
| 13_P | 57_A | 1.754 | 1.00 | |
| 53_R | 77_T | 1.739 | 1.00 | |
| 112_L | 117_L | 1.729 | 1.00 | |
| 171_R | 175_H | 1.716 | 1.00 | |
| 115_D | 119_R | 1.692 | 1.00 | |
| 141_M | 160_L | 1.678 | 1.00 | |
| 132_I | 163_A | 1.668 | 1.00 | |
| 83_D | 87_D | 1.667 | 1.00 | |
| 101_W | 124_S | 1.667 | 1.00 | |
| 12_V | 42_V | 1.642 | 1.00 | |
| 116_D | 208_R | 1.631 | 1.00 | |
| 133_L | 161_W | 1.612 | 1.00 | |
| 195_L | 200_F | 1.608 | 1.00 | |
| 50_R | 118_A | 1.568 | 1.00 | |
| 45_L | 117_L | 1.567 | 1.00 | |
| 86_A | 178_L | 1.556 | 1.00 | |
| 9_C | 53_R | 1.546 | 1.00 | |
| 132_I | 151_I | 1.537 | 1.00 | |
| 15_A | 81_G | 1.523 | 1.00 | |
| 143_R | 159_G | 1.484 | 1.00 | |
| 58_I | 65_F | 1.483 | 1.00 | |
| 156_D | 159_G | 1.48 | 1.00 | |
| 38_L | 65_F | 1.463 | 0.99 | |
| 23_T | 30_L | 1.446 | 0.99 | |
| 113_H | 116_D | 1.402 | 0.99 | |
| 10_A | 45_L | 1.396 | 0.99 | |
| 140_T | 154_T | 1.384 | 0.99 | |
| 143_R | 155_V | 1.383 | 0.99 | |
| 111_C | 223_A | 1.38 | 0.99 | |
| 137_V | 162_H | 1.373 | 0.99 | |
| 103_L | 121_L | 1.371 | 0.99 | |
| 21_M | 220_L | 1.361 | 0.99 | |
| 120_L | 205_V | 1.341 | 0.99 | |
| 195_L | 198_C | 1.316 | 0.99 | |
| 178_L | 194_A | 1.31 | 0.99 | |
| 176_D | 180_R | 1.306 | 0.99 | |
| 134_A | 161_W | 1.3 | 0.99 | |
| 130_G | 170_P | 1.295 | 0.98 | |
| 138_R | 209_A | 1.294 | 0.98 | |
| 162_H | 209_A | 1.284 | 0.98 | |
| 135_A | 164_L | 1.269 | 0.98 | |
| 94_K | 179_T | 1.267 | 0.98 | |
| 31_S | 34_N | 1.267 | 0.98 | |
| 26_P | 62_D | 1.265 | 0.98 | |
| 177_C | 198_C | 1.264 | 0.98 | |
| 135_A | 209_A | 1.258 | 0.98 | |
| 19_R | 84_E | 1.237 | 0.98 | |
| 178_L | 191_E | 1.234 | 0.98 | |
| 18_G | 26_P | 1.23 | 0.98 | |
| 140_T | 189_T | 1.229 | 0.98 | |
| 120_L | 133_L | 1.213 | 0.97 | |
| 11_V | 92_G | 1.204 | 0.97 | |
| 48_H | 51_V | 1.202 | 0.97 | |
| 173_L | 200_F | 1.184 | 0.97 | |
| 93_L | 102_V | 1.182 | 0.97 | |
| 35_Q | 39_E | 1.168 | 0.97 | |
| 96_A | 171_R | 1.165 | 0.97 | |
| 102_V | 171_R | 1.161 | 0.96 | |
| 123_L | 205_V | 1.151 | 0.96 | |
| 119_R | 206_E | 1.142 | 0.96 | |
| 9_C | 96_A | 1.127 | 0.96 | |
| 84_E | 187_T | 1.125 | 0.96 | |
| 164_L | 207_G | 1.119 | 0.95 | |
| 13_P | 41_S | 1.112 | 0.95 | |
| 112_L | 116_D | 1.102 | 0.95 | |
| 35_Q | 40_H | 1.101 | 0.95 | |
| 141_M | 155_V | 1.086 | 0.94 | |
| 63_S | 66_A | 1.082 | 0.94 | |
| 184_E | 197_Y | 1.079 | 0.94 | |
| 212_I | 222_L | 1.075 | 0.94 | |
| 138_R | 216_R | 1.067 | 0.94 | |
| 30_L | 220_L | 1.067 | 0.94 | |
| 39_E | 68_L | 1.057 | 0.93 | |
| 176_D | 200_F | 1.05 | 0.93 | |
| 144_A | 161_W | 1.042 | 0.92 | |
| 135_A | 207_G | 1.036 | 0.92 | |
| 101_W | 168_F | 1.035 | 0.92 | |
| 41_S | 108_A | 1.027 | 0.92 | |
| 39_E | 43_H | 1.024 | 0.92 | |
| 48_H | 121_L | 1.02 | 0.91 | |
| 55_V | 79_V | 1.015 | 0.91 | |
| 176_D | 179_T | 1.008 | 0.91 | |
| 46_L | 74_P | 1.007 | 0.91 | |
| 13_P | 89_V | 1.003 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1i52A | 1 | 0.9873 | 100 | 0.465 | Contact Map | 0.749 |
| 1w55A | 1 | 0.8983 | 100 | 0.497 | Contact Map | 0.711 |
| 4mybA | 1 | 0.9703 | 100 | 0.499 | Contact Map | 0.673 |
| 2yc3A | 1 | 0.9534 | 100 | 0.503 | Contact Map | 0.727 |
| 1vgwA | 6 | 0.9407 | 100 | 0.507 | Contact Map | 0.779 |
| 3f1cA | 2 | 0.9703 | 100 | 0.515 | Contact Map | 0.77 |
| 3q80A | 2 | 0.9492 | 100 | 0.519 | Contact Map | 0.828 |
| 4kt7A | 2 | 0.9661 | 100 | 0.525 | Contact Map | 0.868 |
| 2xwlA | 2 | 0.9364 | 100 | 0.527 | Contact Map | 0.812 |
| 2vshA | 2 | 0.9407 | 100 | 0.528 | Contact Map | 0.78 |
Sequence Conservation (Image Generated using WebLogo v3)