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OPENSEQ.org
YNIA - Uncharacterized protein YniA
UniProt: P77739 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13986
Length: 286 (285)
Sequences: 818
Seq/Len: 2.87
YNIA
Paralog alert: 0.05 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
190_L 216_G 3.066 1.00
155_Q 266_R 2.881 1.00
93_L 202_G 2.455 1.00
61_Q 213_C 2.413 1.00
142_R 145_T 2.291 1.00
260_T 263_N 2.281 1.00
218_R 245_L 2.247 1.00
200_A 209_F 2.212 1.00
44_V 89_V 2.209 1.00
80_G 87_F 2.192 1.00
108_Q 241_S 2.171 1.00
219_E 252_R 2.16 1.00
95_P 209_F 2.145 1.00
218_R 243_S 2.124 1.00
264_R 272_H 2.055 1.00
121_Q 141_R 2.03 1.00
225_L 236_Y 1.952 0.99
140_Q 150_Q 1.908 0.99
104_F 238_G 1.855 0.99
65_L 73_V 1.802 0.99
64_L 124_L 1.796 0.99
106_L 208_I 1.762 0.99
226_P 253_Q 1.746 0.99
72_T 91_D 1.731 0.98
104_F 234_Q 1.717 0.98
128_N 135_Q 1.712 0.98
115_Q 243_S 1.672 0.98
143_W 217_D 1.645 0.98
133_T 263_N 1.633 0.97
103_A 232_P 1.622 0.97
32_A 43_F 1.621 0.97
183_H 217_D 1.611 0.97
107_G 238_G 1.605 0.97
214_Y 220_C 1.597 0.97
218_R 244_P 1.597 0.97
157_E 161_E 1.594 0.97
254_P 257_Q 1.508 0.95
59_A 76_V 1.495 0.95
130_L 263_N 1.484 0.95
22_N 34_H 1.481 0.95
261_L 276_A 1.473 0.95
63_E 75_K 1.472 0.95
190_L 220_C 1.466 0.94
140_Q 145_T 1.465 0.94
24_L 43_F 1.463 0.94
261_L 279_S 1.461 0.94
27_G 32_A 1.461 0.94
240_Q 245_L 1.456 0.94
180_L 183_H 1.439 0.94
104_F 108_Q 1.417 0.93
127_D 136_P 1.417 0.93
228_H 272_H 1.416 0.93
225_L 257_Q 1.413 0.93
197_G 264_R 1.387 0.92
128_N 137_N 1.372 0.91
197_G 229_T 1.353 0.91
248_D 252_R 1.351 0.91
170_D 174_E 1.329 0.90
105_I 108_Q 1.329 0.90
224_M 260_T 1.323 0.89
71_V 109_Q 1.321 0.89
74_P 137_N 1.314 0.89
265_A 276_A 1.313 0.89
95_P 200_A 1.305 0.89
135_Q 155_Q 1.304 0.88
64_L 125_D 1.3 0.88
127_D 190_L 1.3 0.88
225_L 229_T 1.296 0.88
138_T 150_Q 1.293 0.88
224_M 227_L 1.28 0.87
225_L 231_Q 1.279 0.87
279_S 284_L 1.267 0.87
135_Q 259_Y 1.263 0.86
262_L 276_A 1.246 0.85
102_S 213_C 1.242 0.85
133_T 267_L 1.24 0.85
254_P 279_S 1.24 0.85
34_H 41_D 1.237 0.85
227_L 261_L 1.21 0.83
24_L 32_A 1.205 0.83
136_P 150_Q 1.199 0.82
228_H 264_R 1.197 0.82
105_I 109_Q 1.185 0.81
66_S 75_K 1.181 0.81
62_L 211_P 1.171 0.80
264_R 269_G 1.17 0.80
53_P 56_T 1.159 0.79
62_L 88_L 1.157 0.79
265_A 270_G 1.157 0.79
128_N 259_Y 1.156 0.79
90_M 93_L 1.155 0.79
56_T 172_I 1.15 0.78
254_P 282_R 1.146 0.78
155_Q 263_N 1.145 0.78
47_D 55_F 1.145 0.78
57_A 128_N 1.142 0.78
148_A 173_V 1.138 0.77
65_L 70_T 1.134 0.77
197_G 272_H 1.132 0.77
209_F 283_L 1.123 0.76
124_L 128_N 1.12 0.76
197_G 228_H 1.119 0.76
273_L 277_Q 1.118 0.75
29_V 55_F 1.116 0.75
130_L 135_Q 1.113 0.75
37_Y 40_H 1.109 0.75
279_S 283_L 1.105 0.74
225_L 230_E 1.104 0.74
130_L 155_Q 1.099 0.74
151_R 211_P 1.098 0.74
128_N 146_F 1.097 0.74
29_V 47_D 1.09 0.73
192_G 211_P 1.085 0.72
57_A 130_L 1.083 0.72
45_K 55_F 1.083 0.72
79_V 190_L 1.077 0.72
122_F 217_D 1.071 0.71
75_K 91_D 1.065 0.70
143_W 216_G 1.061 0.70
174_E 233_P 1.054 0.69
110_I 258_L 1.051 0.69
260_T 264_R 1.044 0.68
219_E 248_D 1.043 0.68
9_L 13_L 1.037 0.67
20_L 23_E 1.035 0.67
216_G 221_D 1.035 0.67
124_L 220_C 1.03 0.67
264_R 271_Q 1.029 0.67
59_A 79_V 1.028 0.66
60_D 125_D 1.028 0.66
274_V 284_L 1.028 0.66
219_E 244_P 1.026 0.66
148_A 176_I 1.025 0.66
155_Q 259_Y 1.025 0.66
57_A 61_Q 1.023 0.66
147_F 257_Q 1.023 0.66
227_L 260_T 1.022 0.66
64_L 189_L 1.022 0.66
271_Q 274_V 1.02 0.66
99_D 102_S 1.019 0.65
26_G 29_V 1.019 0.65
130_L 224_M 1.019 0.65
27_G 30_H 1.01 0.64
62_L 192_G 1.009 0.64
146_F 214_Y 1.007 0.64
15_E 18_I 1.007 0.64
6_S 18_I 1.004 0.64
221_D 224_M 1.001 0.63
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3d1uA10.9721000.434Contact Map0.61
3jr1A211000.494Contact Map0.664
3tdwA10.92311000.654Contact Map0.468
3r70A10.92661000.684Contact Map0.427
3atsA10.94761000.689Contact Map0.459
3i1aA20.9581000.701Contact Map0.516
3dxpA10.926699.90.707Contact Map0.448
3w0oA10.954599.90.708Contact Map0.383
4gkhA120.825299.90.716Contact Map0.566
2q83A20.947699.90.72Contact Map0.445
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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