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OPENSEQ.org
YKGG - Uncharacterized protein YkgG
UniProt: P77433 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13584
Length: 231 (229)
Sequences: 1129
Seq/Len: 4.93
YKGG
Paralog alert: 0.82 [within 20: 0.55] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
54_A 60_T 4.095 1.00
54_A 225_Y 3.626 1.00
50_F 225_Y 3.253 1.00
143_G 199_I 3.148 1.00
72_E 76_R 2.952 1.00
50_F 137_G 2.899 1.00
60_T 223_A 2.842 1.00
137_G 167_L 2.842 1.00
78_C 129_V 2.583 1.00
54_A 223_A 2.477 1.00
50_F 54_A 2.398 1.00
53_F 57_V 2.3 1.00
76_R 80_E 2.298 1.00
129_V 164_L 2.271 1.00
83_D 129_V 2.136 1.00
60_T 225_Y 2.116 1.00
75_I 106_E 2.078 1.00
51_I 55_S 2.075 1.00
143_G 201_S 2.04 1.00
48_D 52_Q 2.01 1.00
81_L 222_K 2.009 1.00
102_R 106_E 1.933 1.00
161_E 221_V 1.928 1.00
169_K 227_I 1.857 1.00
84_Q 128_K 1.851 1.00
63_E 73_A 1.843 1.00
132_V 163_S 1.774 1.00
87_V 127_A 1.769 1.00
170_S 230_D 1.754 1.00
75_I 102_R 1.726 1.00
128_K 161_E 1.72 1.00
175_R 178_Q 1.658 0.99
78_C 164_L 1.656 0.99
51_I 64_L 1.637 0.99
68_A 72_E 1.625 0.99
66_S 69_K 1.601 0.99
145_V 179_L 1.564 0.99
94_L 166_I 1.562 0.99
63_E 224_V 1.505 0.98
49_A 52_Q 1.504 0.98
42_N 45_Q 1.494 0.98
81_L 162_Y 1.486 0.98
134_A 137_G 1.475 0.98
110_V 123_Q 1.467 0.98
205_S 208_D 1.456 0.98
49_A 53_F 1.452 0.98
134_A 171_T 1.425 0.98
52_Q 55_S 1.411 0.97
69_K 72_E 1.39 0.97
83_D 164_L 1.368 0.97
145_V 199_I 1.368 0.97
166_I 228_I 1.366 0.97
73_A 77_L 1.362 0.97
138_L 179_L 1.354 0.97
89_S 153_G 1.337 0.96
2_D 5_G 1.327 0.96
138_L 173_L 1.299 0.95
58_M 201_S 1.297 0.95
65_T 73_A 1.288 0.95
168_R 171_T 1.286 0.95
130_G 160_P 1.271 0.95
206_T 209_I 1.266 0.94
162_Y 222_K 1.258 0.94
61_R 222_K 1.248 0.94
140_E 175_R 1.238 0.93
97_L 166_I 1.238 0.93
176_V 199_I 1.223 0.93
173_L 179_L 1.214 0.93
102_R 105_Q 1.196 0.92
167_L 227_I 1.191 0.92
204_S 208_D 1.19 0.92
78_C 83_D 1.188 0.92
211_L 214_V 1.185 0.91
50_F 172_I 1.162 0.90
122_S 126_Q 1.146 0.89
134_A 167_L 1.13 0.89
208_D 218_H 1.129 0.89
59_L 215_V 1.125 0.88
85_S 128_K 1.12 0.88
93_R 228_I 1.106 0.87
79_K 106_E 1.106 0.87
202_G 219_G 1.098 0.87
157_S 200_I 1.094 0.86
125_E 159_L 1.092 0.86
129_V 162_Y 1.084 0.86
63_E 77_L 1.083 0.86
101_E 104_Q 1.081 0.85
204_S 218_H 1.073 0.85
124_A 155_S 1.07 0.85
85_S 123_Q 1.07 0.85
134_A 165_F 1.053 0.83
83_D 128_K 1.048 0.83
47_C 172_I 1.043 0.83
204_S 207_A 1.037 0.82
52_Q 166_I 1.034 0.82
64_L 229_E 1.033 0.82
132_V 158_L 1.032 0.82
86_V 131_V 1.031 0.82
162_Y 224_V 1.026 0.81
44_Q 48_D 1.025 0.81
46_R 174_P 1.024 0.81
58_M 205_S 1.014 0.80
164_L 226_L 1.01 0.80
204_S 209_I 1.01 0.80
74_A 226_L 1.007 0.79
82_G 105_Q 1.003 0.79
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2g40A10.87881000.246Contact Map0.725
3cf4A10.839895.70.897Contact Map0.184
1yksA10.3896340.946Contact Map0.137
3brcA20.627713.90.955Contact Map0.107
1v5eA10.398370.961Contact Map0.12
3s93A20.3816.90.961Contact Map0.554
3bn4A60.21654.90.964Contact Map0.106
1q5zA10.50224.70.964Contact Map0.503
2zj8A10.51954.60.964Contact Map0.184
2a1bA120.21654.20.965Contact Map0.12
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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