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OPENSEQ.org
YBAP - Uncharacterized protein YbaP
UniProt: P77301 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13244
Length: 264 (246)
Sequences: 549
Seq/Len: 2.23
YBAP
Paralog alert: 0.04 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
39_S 247_A 4.567 1.00
222_D 227_Q 2.978 1.00
36_L 260_P 2.781 1.00
91_S 94_Q 2.534 1.00
236_L 246_V 2.349 1.00
37_I 245_V 2.205 1.00
248_V 259_L 2.12 1.00
64_L 144_L 2.046 0.99
66_V 157_E 1.832 0.98
163_N 235_K 1.806 0.98
58_L 144_L 1.751 0.98
61_A 245_V 1.747 0.97
163_N 167_M 1.731 0.97
258_N 262_M 1.698 0.97
139_G 200_W 1.682 0.97
58_L 151_Q 1.66 0.96
230_L 262_M 1.636 0.96
225_M 251_L 1.611 0.95
204_P 207_N 1.599 0.95
86_L 120_I 1.592 0.95
140_I 200_W 1.59 0.95
163_N 231_A 1.583 0.95
87_E 113_S 1.579 0.95
176_L 179_L 1.579 0.95
24_I 37_I 1.555 0.94
94_Q 97_N 1.532 0.94
66_V 141_D 1.523 0.93
233_R 259_L 1.515 0.93
157_E 160_G 1.512 0.93
212_L 251_L 1.484 0.92
24_I 39_S 1.484 0.92
65_I 156_I 1.464 0.91
65_I 232_W 1.458 0.91
226_H 257_G 1.454 0.91
37_I 54_L 1.443 0.91
222_D 226_H 1.437 0.90
94_Q 180_D 1.418 0.90
43_G 47_M 1.392 0.88
199_W 211_T 1.386 0.88
144_L 247_A 1.378 0.88
210_I 214_N 1.372 0.87
233_R 258_N 1.369 0.87
116_P 169_L 1.361 0.87
62_D 243_R 1.34 0.86
99_Q 108_S 1.323 0.85
49_P 200_W 1.315 0.84
66_V 250_A 1.307 0.84
162_E 166_A 1.305 0.84
221_Y 226_H 1.298 0.83
224_L 260_P 1.296 0.83
23_A 200_W 1.286 0.82
121_A 126_A 1.281 0.82
84_E 89_R 1.275 0.82
152_H 263_L 1.262 0.81
54_L 57_K 1.259 0.80
97_N 100_H 1.255 0.80
43_G 139_G 1.236 0.79
260_P 264_R 1.236 0.79
92_E 238_A 1.228 0.78
66_V 145_L 1.227 0.78
65_I 246_V 1.226 0.78
116_P 175_G 1.22 0.77
41_H 249_G 1.219 0.77
54_L 61_A 1.203 0.76
231_A 235_K 1.201 0.76
22_P 118_W 1.193 0.75
256_E 261_Q 1.187 0.75
232_W 245_V 1.174 0.74
57_K 245_V 1.165 0.73
243_R 259_L 1.16 0.72
27_T 34_F 1.155 0.72
66_V 70_V 1.154 0.72
43_G 140_I 1.152 0.72
254_Y 258_N 1.141 0.71
63_A 244_Y 1.138 0.70
49_P 139_G 1.135 0.70
48_A 247_A 1.126 0.69
100_H 162_E 1.107 0.67
64_L 155_V 1.099 0.66
63_A 156_I 1.094 0.66
27_T 80_L 1.088 0.65
165_I 207_N 1.086 0.65
137_E 161_A 1.077 0.64
172_P 176_L 1.077 0.64
44_S 47_M 1.069 0.63
232_W 253_L 1.065 0.63
65_I 251_L 1.064 0.63
196_M 199_W 1.063 0.63
223_V 227_Q 1.054 0.62
253_L 260_P 1.052 0.61
197_M 251_L 1.051 0.61
258_N 261_Q 1.049 0.61
102_S 112_F 1.048 0.61
200_W 209_D 1.045 0.61
76_P 144_L 1.045 0.61
199_W 207_N 1.043 0.60
39_S 49_P 1.042 0.60
29_P 251_L 1.036 0.60
58_L 247_A 1.03 0.59
121_A 178_L 1.029 0.59
89_R 160_G 1.029 0.59
33_H 243_R 1.029 0.59
133_G 200_W 1.026 0.59
35_H 245_V 1.025 0.58
40_I 140_I 1.025 0.58
145_L 157_E 1.02 0.58
22_P 200_W 1.019 0.58
34_F 49_P 1.016 0.57
200_W 203_A 1.015 0.57
47_M 201_L 1.014 0.57
229_N 255_G 1.013 0.57
87_E 95_L 1.012 0.57
152_H 166_A 1.012 0.57
33_H 139_G 1.011 0.57
86_L 196_M 1.005 0.56
38_G 41_H 1.004 0.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2g5gX10.780382.20.936Contact Map0.329
3f14A10.276523.20.958Contact Map0.367
4lmiA20.318222.10.958Contact Map0.47
1nwwA20.352312.80.962Contact Map0.546
3f40A10.306810.30.964Contact Map0.369
1ohpA40.29558.80.965Contact Map0.4
2zuxA20.21598.60.965Contact Map0.053
3ebtA10.29558.40.965Contact Map0.413
4kvhA10.295580.966Contact Map0.379
4mjdA20.295580.966Contact Map0.389
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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