| UniProt: | P76561 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14195 | ||
| Length: | 232 (205) | ||
| Sequences: | 1778 | ||
| Seq/Len: | 8.67 |
| YPFH
Paralog alert: 0.21 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 114_A | 136_G | 3.62 | 1.00 | |
| 121_I | 131_V | 3.543 | 1.00 | |
| 66_F | 137_R | 3.262 | 1.00 | |
| 114_A | 133_A | 3.003 | 1.00 | |
| 186_V | 200_F | 2.927 | 1.00 | |
| 134_F | 201_A | 2.882 | 1.00 | |
| 164_L | 185_I | 2.628 | 1.00 | |
| 27_D | 31_A | 2.572 | 1.00 | |
| 132_I | 201_A | 2.492 | 1.00 | |
| 29_P | 52_G | 2.481 | 1.00 | |
| 168_V | 185_I | 2.417 | 1.00 | |
| 106_A | 205_L | 2.325 | 1.00 | |
| 17_Q | 46_A | 2.322 | 1.00 | |
| 19_L | 48_V | 2.145 | 1.00 | |
| 182_T | 207_Y | 2.138 | 1.00 | |
| 20_L | 91_V | 2.04 | 1.00 | |
| 106_A | 130_R | 1.968 | 1.00 | |
| 22_F | 87_F | 1.96 | 1.00 | |
| 157_G | 187_E | 1.931 | 1.00 | |
| 154_I | 197_S | 1.816 | 1.00 | |
| 88_I | 120_S | 1.77 | 1.00 | |
| 18_L | 94_W | 1.756 | 1.00 | |
| 133_A | 153_L | 1.733 | 1.00 | |
| 117_V | 131_V | 1.731 | 1.00 | |
| 160_P | 190_G | 1.627 | 1.00 | |
| 15_A | 18_L | 1.621 | 1.00 | |
| 121_I | 149_T | 1.603 | 1.00 | |
| 11_P | 15_A | 1.58 | 1.00 | |
| 151_I | 179_G | 1.576 | 1.00 | |
| 108_I | 132_I | 1.537 | 1.00 | |
| 116_M | 136_G | 1.532 | 1.00 | |
| 189_L | 194_D | 1.531 | 1.00 | |
| 157_G | 185_I | 1.524 | 1.00 | |
| 118_L | 153_L | 1.516 | 1.00 | |
| 89_E | 93_Y | 1.508 | 1.00 | |
| 171_Q | 175_I | 1.504 | 1.00 | |
| 164_L | 168_V | 1.496 | 1.00 | |
| 202_L | 206_R | 1.48 | 1.00 | |
| 135_N | 155_H | 1.48 | 1.00 | |
| 184_D | 200_F | 1.463 | 1.00 | |
| 52_G | 63_R | 1.446 | 0.99 | |
| 56_P | 82_A | 1.433 | 0.99 | |
| 16_Q | 104_A | 1.426 | 0.99 | |
| 111_S | 191_H | 1.415 | 0.99 | |
| 171_Q | 181_V | 1.392 | 0.99 | |
| 167_A | 183_L | 1.386 | 0.99 | |
| 101_G | 104_A | 1.374 | 0.99 | |
| 84_M | 119_E | 1.371 | 0.99 | |
| 77_Q | 81_D | 1.367 | 0.99 | |
| 92_R | 96_K | 1.365 | 0.99 | |
| 118_L | 133_A | 1.342 | 0.99 | |
| 152_H | 197_S | 1.331 | 0.99 | |
| 157_G | 188_D | 1.316 | 0.99 | |
| 130_R | 150_T | 1.312 | 0.99 | |
| 17_Q | 104_A | 1.296 | 0.99 | |
| 28_N | 31_A | 1.282 | 0.98 | |
| 58_G | 62_G | 1.278 | 0.98 | |
| 152_H | 200_F | 1.266 | 0.98 | |
| 21_L | 32_M | 1.264 | 0.98 | |
| 85_P | 89_E | 1.258 | 0.98 | |
| 106_A | 208_T | 1.254 | 0.98 | |
| 135_N | 197_S | 1.251 | 0.98 | |
| 88_I | 124_E | 1.227 | 0.98 | |
| 91_V | 105_T | 1.224 | 0.98 | |
| 158_E | 187_E | 1.197 | 0.97 | |
| 119_E | 123_A | 1.193 | 0.97 | |
| 86_T | 89_E | 1.191 | 0.97 | |
| 87_F | 116_M | 1.179 | 0.97 | |
| 115_I | 162_I | 1.178 | 0.97 | |
| 133_A | 136_G | 1.164 | 0.97 | |
| 115_I | 137_R | 1.154 | 0.96 | |
| 172_E | 176_S | 1.142 | 0.96 | |
| 155_H | 167_A | 1.136 | 0.96 | |
| 172_E | 175_I | 1.132 | 0.96 | |
| 56_P | 64_Q | 1.129 | 0.96 | |
| 173_A | 176_S | 1.12 | 0.95 | |
| 29_P | 51_V | 1.111 | 0.95 | |
| 93_Y | 97_Q | 1.104 | 0.95 | |
| 154_I | 186_V | 1.103 | 0.95 | |
| 58_G | 64_Q | 1.098 | 0.95 | |
| 49_V | 94_W | 1.095 | 0.95 | |
| 157_G | 164_L | 1.092 | 0.94 | |
| 164_L | 183_L | 1.092 | 0.94 | |
| 111_S | 159_D | 1.083 | 0.94 | |
| 168_V | 183_L | 1.082 | 0.94 | |
| 152_H | 184_D | 1.08 | 0.94 | |
| 94_W | 98_S | 1.076 | 0.94 | |
| 24_G | 111_S | 1.074 | 0.94 | |
| 30_V | 52_G | 1.07 | 0.94 | |
| 92_R | 126_G | 1.066 | 0.94 | |
| 85_P | 88_I | 1.055 | 0.93 | |
| 134_F | 197_S | 1.055 | 0.93 | |
| 33_G | 50_S | 1.05 | 0.93 | |
| 56_P | 63_R | 1.046 | 0.93 | |
| 75_N | 79_R | 1.04 | 0.92 | |
| 168_V | 172_E | 1.038 | 0.92 | |
| 11_P | 14_P | 1.035 | 0.92 | |
| 100_V | 105_T | 1.031 | 0.92 | |
| 92_R | 124_E | 1.027 | 0.92 | |
| 21_L | 36_G | 1.026 | 0.92 | |
| 95_Q | 105_T | 1.025 | 0.92 | |
| 204_H | 208_T | 1.023 | 0.92 | |
| 118_L | 138_Y | 1.022 | 0.92 | |
| 25_V | 68_V | 1.019 | 0.91 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1fj2A | 2 | 0.9052 | 100 | 0.516 | Contact Map | 0.803 |
| 3b5eA | 2 | 0.8879 | 100 | 0.517 | Contact Map | 0.629 |
| 4f21A | 8 | 0.9009 | 100 | 0.525 | Contact Map | 0.734 |
| 3og9A | 2 | 0.8664 | 100 | 0.526 | Contact Map | 0.66 |
| 1auoA | 2 | 0.8879 | 100 | 0.527 | Contact Map | 0.833 |
| 2r8bA | 2 | 0.875 | 100 | 0.533 | Contact Map | 0.734 |
| 3u0vA | 1 | 0.931 | 100 | 0.54 | Contact Map | 0.777 |
| 4fhzA | 1 | 0.9828 | 100 | 0.54 | Contact Map | 0.702 |
| 4h0cA | 2 | 0.8491 | 100 | 0.553 | Contact Map | 0.779 |
| 2h1iA | 3 | 0.8621 | 100 | 0.554 | Contact Map | 0.758 |
Sequence Conservation (Image Generated using WebLogo v3)