| UniProt: | P76458 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11669 | ||
| Length: | 220 (218) | ||
| Sequences: | 1580 | ||
| Seq/Len: | 7.25 |
| ATOD
Paralog alert: 0.43 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 161_T | 194_E | 3.685 | 1.00 | |
| 135_T | 140_T | 3.483 | 1.00 | |
| 120_P | 139_K | 3.422 | 1.00 | |
| 165_L | 187_V | 3.311 | 1.00 | |
| 198_L | 203_I | 3.17 | 1.00 | |
| 156_A | 165_L | 3.137 | 1.00 | |
| 16_R | 19_M | 2.999 | 1.00 | |
| 167_Y | 205_T | 2.907 | 1.00 | |
| 137_D | 145_R | 2.783 | 1.00 | |
| 83_E | 86_R | 2.737 | 1.00 | |
| 71_R | 94_D | 2.594 | 1.00 | |
| 17_D | 45_R | 2.574 | 1.00 | |
| 22_M | 149_A | 2.521 | 1.00 | |
| 158_R | 191_E | 2.45 | 1.00 | |
| 58_D | 66_V | 2.403 | 1.00 | |
| 7_T | 10_D | 2.366 | 1.00 | |
| 9_Q | 41_E | 2.305 | 1.00 | |
| 18_G | 46_D | 2.245 | 1.00 | |
| 46_D | 71_R | 2.176 | 1.00 | |
| 22_M | 107_I | 2.174 | 1.00 | |
| 123_V | 140_T | 2.159 | 1.00 | |
| 133_T | 140_T | 2.119 | 1.00 | |
| 15_F | 39_L | 2.118 | 1.00 | |
| 157_H | 168_Q | 2.09 | 1.00 | |
| 37_E | 63_P | 2.077 | 1.00 | |
| 38_A | 41_E | 1.969 | 1.00 | |
| 48_T | 74_I | 1.905 | 1.00 | |
| 50_I | 147_L | 1.889 | 1.00 | |
| 39_L | 153_L | 1.852 | 1.00 | |
| 86_R | 90_S | 1.842 | 1.00 | |
| 161_T | 195_T | 1.837 | 1.00 | |
| 68_G | 87_R | 1.824 | 1.00 | |
| 118_L | 134_L | 1.823 | 1.00 | |
| 87_R | 92_E | 1.779 | 1.00 | |
| 159_C | 189_P | 1.768 | 1.00 | |
| 159_C | 192_L | 1.734 | 1.00 | |
| 50_I | 149_A | 1.713 | 1.00 | |
| 159_C | 187_V | 1.689 | 1.00 | |
| 158_R | 166_T | 1.664 | 1.00 | |
| 152_A | 182_A | 1.635 | 1.00 | |
| 15_F | 186_L | 1.601 | 1.00 | |
| 23_V | 153_L | 1.594 | 1.00 | |
| 162_L | 195_T | 1.588 | 1.00 | |
| 148_R | 183_D | 1.556 | 1.00 | |
| 194_E | 197_E | 1.555 | 1.00 | |
| 64_L | 69_R | 1.547 | 1.00 | |
| 96_V | 106_Q | 1.542 | 1.00 | |
| 17_D | 43_G | 1.537 | 1.00 | |
| 10_D | 13_G | 1.536 | 1.00 | |
| 133_T | 142_L | 1.517 | 0.99 | |
| 68_G | 92_E | 1.517 | 0.99 | |
| 116_G | 143_L | 1.516 | 0.99 | |
| 199_Q | 202_H | 1.512 | 0.99 | |
| 107_I | 178_I | 1.499 | 0.99 | |
| 19_M | 151_L | 1.494 | 0.99 | |
| 105_E | 108_R | 1.48 | 0.99 | |
| 160_D | 164_N | 1.478 | 0.99 | |
| 14_F | 212_H | 1.465 | 0.99 | |
| 35_L | 153_L | 1.462 | 0.99 | |
| 48_T | 72_K | 1.456 | 0.99 | |
| 6_M | 10_D | 1.45 | 0.99 | |
| 72_K | 94_D | 1.426 | 0.99 | |
| 40_L | 69_R | 1.414 | 0.99 | |
| 22_M | 178_I | 1.413 | 0.99 | |
| 110_G | 148_R | 1.4 | 0.99 | |
| 192_L | 215_V | 1.377 | 0.99 | |
| 161_T | 197_E | 1.346 | 0.98 | |
| 20_T | 50_I | 1.318 | 0.98 | |
| 15_F | 19_M | 1.311 | 0.98 | |
| 114_L | 117_F | 1.31 | 0.98 | |
| 184_I | 212_H | 1.299 | 0.98 | |
| 98_V | 106_Q | 1.298 | 0.98 | |
| 8_L | 38_A | 1.293 | 0.98 | |
| 179_A | 185_T | 1.268 | 0.97 | |
| 132_Q | 137_D | 1.265 | 0.97 | |
| 12_T | 38_A | 1.265 | 0.97 | |
| 15_F | 151_L | 1.264 | 0.97 | |
| 44_V | 69_R | 1.262 | 0.97 | |
| 6_M | 212_H | 1.247 | 0.97 | |
| 72_K | 96_V | 1.245 | 0.97 | |
| 106_Q | 146_P | 1.23 | 0.97 | |
| 126_V | 129_E | 1.214 | 0.96 | |
| 191_E | 197_E | 1.208 | 0.96 | |
| 40_L | 63_P | 1.194 | 0.96 | |
| 118_L | 143_L | 1.183 | 0.96 | |
| 115_G | 136_L | 1.182 | 0.96 | |
| 155_R | 216_S | 1.18 | 0.96 | |
| 169_L | 201_D | 1.179 | 0.95 | |
| 12_T | 15_F | 1.178 | 0.95 | |
| 151_L | 184_I | 1.175 | 0.95 | |
| 65_I | 87_R | 1.175 | 0.95 | |
| 107_I | 181_A | 1.137 | 0.94 | |
| 109_C | 117_F | 1.127 | 0.94 | |
| 108_R | 112_A | 1.12 | 0.94 | |
| 34_R | 216_S | 1.108 | 0.93 | |
| 102_T | 119_T | 1.108 | 0.93 | |
| 135_T | 138_G | 1.108 | 0.93 | |
| 9_Q | 38_A | 1.094 | 0.93 | |
| 172_R | 201_D | 1.094 | 0.93 | |
| 40_L | 66_V | 1.082 | 0.92 | |
| 22_M | 50_I | 1.079 | 0.92 | |
| 178_I | 182_A | 1.059 | 0.91 | |
| 154_I | 178_I | 1.041 | 0.90 | |
| 184_I | 187_V | 1.02 | 0.89 | |
| 116_G | 134_L | 1.005 | 0.88 | |
| 67_N | 92_E | 1.002 | 0.87 | |
| 105_E | 117_F | 1.002 | 0.87 | |
| 158_R | 193_V | 1 | 0.87 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3cdkA | 2 | 1 | 100 | 0.203 | Contact Map | 0.863 |
| 3rrlA | 2 | 1 | 100 | 0.206 | Contact Map | 0.773 |
| 1k6dA | 2 | 1 | 100 | 0.209 | Contact Map | 0.805 |
| 3k6mA | 4 | 0.9955 | 100 | 0.211 | Contact Map | 0.871 |
| 4kgbA | 2 | 1 | 100 | 0.217 | Contact Map | 0.833 |
| 1poiA | 2 | 0.9682 | 100 | 0.24 | Contact Map | 0.772 |
| 2ahuA | 4 | 1 | 100 | 0.252 | Contact Map | 0.799 |
| 2hj0A | 2 | 0.8182 | 100 | 0.508 | Contact Map | 0.635 |
| 3qliA | 2 | 0.8364 | 100 | 0.521 | Contact Map | 0.606 |
| 1xr4A | 2 | 0.8091 | 100 | 0.521 | Contact Map | 0.643 |
Sequence Conservation (Image Generated using WebLogo v3)