May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
MNTP - Probable manganese efflux pump MntP
UniProt: P76264 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14012
Length: 188 (186)
Sequences: 790
Seq/Len: 4.25
MNTP
Paralog alert: 0.16 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
74_F 182_L 3.4 1.00
48_T 141_G 3.183 1.00
18_F 151_G 2.455 1.00
69_N 185_H 2.401 1.00
83_R 86_I 2.328 1.00
88_G 168_I 2.139 1.00
17_A 144_T 2.083 1.00
82_G 86_I 1.87 1.00
12_G 15_M 1.867 1.00
172_L 176_G 1.851 1.00
42_I 112_A 1.802 1.00
86_I 90_R 1.781 1.00
139_A 143_A 1.758 0.99
175_I 178_G 1.751 0.99
10_A 139_A 1.723 0.99
13_M 118_D 1.596 0.99
42_I 108_L 1.584 0.99
9_L 177_I 1.555 0.98
155_G 159_G 1.501 0.98
147_M 151_G 1.433 0.97
36_A 40_G 1.404 0.96
22_I 154_V 1.396 0.96
69_N 73_A 1.396 0.96
65_V 69_N 1.396 0.96
46_V 50_T 1.369 0.96
17_A 51_P 1.368 0.96
6_T 136_T 1.362 0.96
47_E 115_T 1.361 0.96
43_F 47_E 1.356 0.95
21_S 148_S 1.355 0.95
7_V 143_A 1.354 0.95
112_A 137_A 1.292 0.94
43_F 115_T 1.288 0.93
6_T 10_A 1.284 0.93
144_T 148_S 1.273 0.93
99_P 103_H 1.269 0.93
81_G 171_G 1.244 0.92
73_A 115_T 1.225 0.91
36_A 118_D 1.213 0.90
19_A 121_A 1.205 0.90
70_H 185_H 1.196 0.90
154_V 158_I 1.195 0.90
6_T 139_A 1.192 0.89
10_A 147_M 1.189 0.89
165_K 177_I 1.172 0.88
161_I 165_K 1.151 0.87
75_V 79_F 1.147 0.87
43_F 54_G 1.143 0.87
47_E 118_D 1.136 0.86
46_V 116_S 1.134 0.86
22_I 151_G 1.123 0.85
78_I 82_G 1.117 0.85
73_A 181_I 1.117 0.85
45_A 76_L 1.116 0.85
85_I 171_G 1.115 0.85
14_S 47_E 1.114 0.85
108_L 176_G 1.113 0.85
95_E 134_I 1.103 0.84
10_A 148_S 1.101 0.84
43_F 140_I 1.1 0.84
34_S 38_R 1.1 0.84
129_L 181_I 1.099 0.84
49_L 53_I 1.097 0.83
114_A 177_I 1.094 0.83
166_A 173_V 1.092 0.83
47_E 119_A 1.09 0.83
84_M 170_G 1.09 0.83
118_D 170_G 1.088 0.83
118_D 122_V 1.084 0.82
10_A 68_W 1.076 0.82
53_I 75_V 1.073 0.82
62_S 127_A 1.072 0.81
14_S 143_A 1.065 0.81
164_K 168_I 1.057 0.80
66_L 69_N 1.056 0.80
81_G 178_G 1.055 0.80
66_L 186_F 1.055 0.80
24_K 111_T 1.049 0.80
75_V 146_I 1.044 0.79
23_G 40_G 1.039 0.79
69_N 181_I 1.037 0.78
42_I 105_F 1.035 0.78
156_R 162_I 1.034 0.78
47_E 50_T 1.032 0.78
83_R 177_I 1.031 0.78
47_E 111_T 1.03 0.78
154_V 168_I 1.019 0.77
7_V 139_A 1.018 0.77
119_A 140_I 1.016 0.76
25_G 151_G 1.015 0.76
83_R 87_E 1.013 0.76
17_A 166_A 1.01 0.76
83_R 113_I 1.006 0.75
48_T 137_A 1.002 0.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4jr9A10.968112.60.944Contact Map0.016
3wdoA10.94686.80.95Contact Map0.088
2cfqA10.46815.60.952Contact Map0.242
3h90A40.45213.50.956Contact Map0.226
4ikvA10.54263.30.957Contact Map0.096
3o7qA10.55322.60.959Contact Map0.068
1pw4A10.52132.40.96Contact Map0.154
3tdsE50.5162.30.96Contact Map0.244
2gfpA20.46812.30.96Contact Map0.275
3j1zP20.52.20.961Contact Map0.2
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.0375 seconds.