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OPENSEQ.org

YNEE - UPF0187 protein YneE
UniProt: P76146 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13813
Length: 304 (304)
Sequences: 707
Seq/Len: 2.33

YNEE
Paralog alert: 0.17 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
85_L 197_G 4.985 1.00
89_L 194_V 3.296 1.00
91_I 196_A 3.091 1.00
77_A 84_K 2.883 1.00
122_H 125_R 2.784 1.00
127_T 156_A 2.333 1.00
99_E 185_N 2.113 1.00
265_E 268_D 2.076 0.99
93_S 117_Q 2.045 0.99
257_E 267_N 1.974 0.99
126_M 136_V 1.946 0.99
81_E 200_R 1.918 0.99
77_A 80_V 1.907 0.99
120_F 195_L 1.875 0.99
114_A 282_L 1.823 0.98
277_A 281_D 1.812 0.98
263_G 268_D 1.774 0.98
21_L 28_L 1.701 0.97
93_S 278_I 1.67 0.97
259_E 268_D 1.638 0.96
113_F 163_M 1.627 0.96
92_A 190_D 1.54 0.94
190_D 193_A 1.525 0.94
39_I 237_T 1.524 0.94
99_E 187_R 1.489 0.93
295_I 298_D 1.468 0.92
81_E 84_K 1.446 0.91
212_L 216_R 1.441 0.91
32_F 242_V 1.434 0.91
123_C 159_I 1.433 0.91
193_A 196_A 1.421 0.90
88_Q 194_V 1.417 0.90
90_M 274_I 1.411 0.90
87_G 91_I 1.407 0.90
89_L 124_L 1.37 0.88
91_I 193_A 1.365 0.88
203_Y 277_A 1.365 0.88
81_E 87_G 1.36 0.88
98_R 192_S 1.344 0.87
111_R 115_R 1.332 0.86
98_R 164_G 1.331 0.86
221_F 258_L 1.329 0.86
61_G 246_Y 1.325 0.86
201_I 274_I 1.318 0.85
176_L 184_L 1.309 0.85
126_M 131_Q 1.3 0.84
31_N 35_S 1.283 0.83
34_F 38_V 1.28 0.83
94_R 199_E 1.273 0.82
10_L 14_F 1.247 0.81
116_L 166_W 1.234 0.80
213_I 250_S 1.234 0.80
57_F 216_R 1.221 0.79
217_T 247_T 1.217 0.78
52_F 229_L 1.216 0.78
271_L 275_C 1.213 0.78
25_S 30_L 1.211 0.78
127_T 154_S 1.21 0.78
290_E 296_L 1.209 0.78
29_L 50_I 1.208 0.78
60_L 241_S 1.206 0.77
67_F 252_D 1.2 0.77
97_L 282_L 1.195 0.77
57_F 224_M 1.194 0.77
293_A 297_P 1.19 0.76
75_G 221_F 1.189 0.76
229_L 275_C 1.18 0.75
296_L 299_R 1.176 0.75
100_V 110_V 1.164 0.74
276_N 280_I 1.163 0.74
188_L 191_I 1.162 0.74
208_F 212_L 1.161 0.74
66_I 254_L 1.161 0.74
33_L 40_F 1.16 0.74
66_I 72_N 1.159 0.73
40_F 44_W 1.155 0.73
67_F 251_L 1.154 0.73
164_G 188_L 1.153 0.73
65_A 69_G 1.152 0.73
125_R 271_L 1.151 0.73
73_N 87_G 1.142 0.72
80_V 87_G 1.138 0.72
230_V 235_Y 1.135 0.71
120_F 191_I 1.133 0.71
80_V 83_R 1.129 0.71
65_A 250_S 1.129 0.71
46_T 49_G 1.122 0.70
160_L 192_S 1.121 0.70
16_W 23_K 1.114 0.69
35_S 241_S 1.114 0.69
75_G 258_L 1.113 0.69
115_R 283_L 1.106 0.68
136_V 140_Y 1.106 0.68
69_G 73_N 1.103 0.68
117_Q 163_M 1.101 0.68
32_F 106_D 1.098 0.68
11_R 15_V 1.096 0.67
125_R 275_C 1.093 0.67
91_I 199_E 1.09 0.67
39_I 238_P 1.078 0.65
104_L 110_V 1.075 0.65
179_I 182_I 1.071 0.65
269_L 272_D 1.07 0.65
143_T 148_R 1.069 0.65
112_E 166_W 1.067 0.64
191_I 281_D 1.067 0.64
280_I 292_P 1.065 0.64
291_I 302_Q 1.063 0.64
143_T 146_L 1.063 0.64
87_G 200_R 1.061 0.64
299_R 304_T 1.057 0.63
172_R 176_L 1.054 0.63
298_D 303_L 1.052 0.63
118_I 282_L 1.05 0.62
62_V 120_F 1.049 0.62
227_F 267_N 1.049 0.62
219_Y 223_I 1.046 0.62
89_L 179_I 1.042 0.62
85_L 198_C 1.041 0.62
95_S 192_S 1.041 0.62
90_M 127_T 1.038 0.61
263_G 269_L 1.032 0.61
298_D 302_Q 1.032 0.61
29_L 34_F 1.031 0.60
246_Y 251_L 1.029 0.60
227_F 245_S 1.029 0.60
83_R 86_W 1.026 0.60
294_K 300_H 1.026 0.60
21_L 33_L 1.025 0.60
220_L 258_L 1.023 0.60
103_T 159_I 1.021 0.59
222_C 267_N 1.02 0.59
129_R 271_L 1.019 0.59
142_K 145_D 1.017 0.59
86_W 278_I 1.014 0.58
92_A 191_I 1.014 0.58
214_L 257_E 1.012 0.58
205_P 267_N 1.012 0.58
254_L 258_L 1.011 0.58
89_L 163_M 1.008 0.58
213_I 246_Y 1.008 0.58
277_A 297_P 1.007 0.58
146_L 251_L 1.006 0.58
135_E 138_A 1.002 0.57
28_L 242_V 1.002 0.57
67_F 248_F 1.001 0.57
94_R 196_A 1 0.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2azeC10.15135.70.975Contact Map0.181
3lw5I10.098750.976Contact Map0
1jb0I10.1253.90.977Contact Map0
2wscI10.13163.80.977Contact Map0
2l1wB10.08223.10.978Contact Map1
2l16A10.23682.50.979Contact Map0.423
4a56A10.28952.20.98Contact Map0.327
2jz3A10.118420.98Contact Map0.333
4bk4A20.302620.98Contact Map0.136
4g1aA30.1021.90.981Contact Map1

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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