| UniProt: | P76038 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13909 | ||
| Length: | 254 (245) | ||
| Sequences: | 1273 | ||
| Seq/Len: | 5.20 |
| PUUD
Paralog alert: 0.25 [within 20: 0.02] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 196_V | 199_R | 3.602 | 1.00 | |
| 35_I | 40_G | 3.483 | 1.00 | |
| 81_E | 188_K | 3.055 | 1.00 | |
| 100_I | 110_I | 2.762 | 1.00 | |
| 194_L | 208_V | 2.726 | 1.00 | |
| 165_G | 197_E | 2.583 | 1.00 | |
| 120_L | 216_A | 2.565 | 1.00 | |
| 62_L | 65_I | 2.561 | 1.00 | |
| 112_A | 120_L | 2.557 | 1.00 | |
| 11_G | 62_L | 2.45 | 1.00 | |
| 191_S | 194_L | 2.38 | 1.00 | |
| 102_A | 106_R | 2.321 | 1.00 | |
| 215_F | 239_G | 2.297 | 1.00 | |
| 14_M | 44_A | 2.289 | 1.00 | |
| 121_V | 191_S | 2.265 | 1.00 | |
| 93_D | 115_R | 2.258 | 1.00 | |
| 197_E | 209_S | 2.222 | 1.00 | |
| 129_H | 188_K | 2.202 | 1.00 | |
| 124_T | 194_L | 2.165 | 1.00 | |
| 190_V | 196_V | 2.044 | 1.00 | |
| 67_L | 100_I | 2.001 | 1.00 | |
| 10_I | 64_G | 1.973 | 1.00 | |
| 73_N | 184_G | 1.972 | 1.00 | |
| 97_M | 123_A | 1.966 | 1.00 | |
| 240_F | 244_C | 1.92 | 1.00 | |
| 35_I | 66_Y | 1.872 | 1.00 | |
| 120_L | 218_G | 1.833 | 1.00 | |
| 162_E | 199_R | 1.779 | 1.00 | |
| 92_R | 96_S | 1.755 | 1.00 | |
| 219_V | 236_L | 1.71 | 1.00 | |
| 65_I | 110_I | 1.701 | 1.00 | |
| 131_K | 184_G | 1.681 | 1.00 | |
| 9_V | 61_K | 1.652 | 0.99 | |
| 100_I | 123_A | 1.622 | 0.99 | |
| 239_G | 243_A | 1.618 | 0.99 | |
| 101_N | 105_E | 1.607 | 0.99 | |
| 187_A | 208_V | 1.599 | 0.99 | |
| 107_R | 214_P | 1.591 | 0.99 | |
| 83_G | 87_D | 1.586 | 0.99 | |
| 66_Y | 240_F | 1.579 | 0.99 | |
| 65_I | 103_A | 1.567 | 0.99 | |
| 102_A | 105_E | 1.559 | 0.99 | |
| 10_I | 40_G | 1.559 | 0.99 | |
| 11_G | 45_L | 1.557 | 0.99 | |
| 186_G | 204_L | 1.547 | 0.99 | |
| 157_H | 181_S | 1.535 | 0.99 | |
| 158_E | 178_W | 1.532 | 0.99 | |
| 165_G | 209_S | 1.517 | 0.99 | |
| 40_G | 241_I | 1.512 | 0.99 | |
| 190_V | 208_V | 1.509 | 0.99 | |
| 65_I | 99_I | 1.497 | 0.99 | |
| 122_V | 128_L | 1.494 | 0.99 | |
| 132_L | 204_L | 1.464 | 0.98 | |
| 37_H | 234_R | 1.455 | 0.98 | |
| 215_F | 243_A | 1.451 | 0.98 | |
| 189_V | 192_P | 1.45 | 0.98 | |
| 104_L | 124_T | 1.441 | 0.98 | |
| 158_E | 176_N | 1.434 | 0.98 | |
| 157_H | 206_E | 1.408 | 0.98 | |
| 124_T | 191_S | 1.39 | 0.97 | |
| 163_E | 168_S | 1.385 | 0.97 | |
| 121_V | 127_S | 1.374 | 0.97 | |
| 195_R | 211_I | 1.372 | 0.97 | |
| 160_Q | 176_N | 1.371 | 0.97 | |
| 163_E | 175_S | 1.369 | 0.97 | |
| 103_A | 108_I | 1.368 | 0.97 | |
| 56_E | 102_A | 1.362 | 0.97 | |
| 60_P | 106_R | 1.355 | 0.97 | |
| 79_Y | 128_L | 1.339 | 0.97 | |
| 114_C | 222_H | 1.338 | 0.97 | |
| 43_I | 61_K | 1.336 | 0.97 | |
| 161_V | 198_A | 1.336 | 0.97 | |
| 155_P | 226_N | 1.324 | 0.96 | |
| 159_V | 179_V | 1.322 | 0.96 | |
| 162_E | 195_R | 1.32 | 0.96 | |
| 234_R | 238_E | 1.281 | 0.95 | |
| 81_E | 130_R | 1.279 | 0.95 | |
| 166_L | 209_S | 1.278 | 0.95 | |
| 242_T | 245_Q | 1.273 | 0.95 | |
| 33_N | 36_I | 1.272 | 0.95 | |
| 159_V | 221_W | 1.265 | 0.95 | |
| 167_L | 198_A | 1.261 | 0.95 | |
| 100_I | 119_E | 1.255 | 0.95 | |
| 73_N | 131_K | 1.253 | 0.95 | |
| 210_V | 216_A | 1.252 | 0.95 | |
| 194_L | 216_A | 1.238 | 0.94 | |
| 111_F | 236_L | 1.235 | 0.94 | |
| 12_V | 32_L | 1.234 | 0.94 | |
| 117_L | 186_G | 1.22 | 0.93 | |
| 13_V | 96_S | 1.212 | 0.93 | |
| 12_V | 35_I | 1.199 | 0.93 | |
| 68_P | 92_R | 1.197 | 0.93 | |
| 30_K | 225_W | 1.195 | 0.93 | |
| 121_V | 126_G | 1.184 | 0.92 | |
| 208_V | 218_G | 1.178 | 0.92 | |
| 64_G | 244_C | 1.168 | 0.91 | |
| 59_L | 108_I | 1.162 | 0.91 | |
| 200_S | 204_L | 1.157 | 0.91 | |
| 13_V | 68_P | 1.154 | 0.91 | |
| 170_L | 239_G | 1.145 | 0.90 | |
| 29_E | 33_N | 1.118 | 0.89 | |
| 161_V | 177_F | 1.114 | 0.89 | |
| 97_M | 101_N | 1.112 | 0.88 | |
| 101_N | 123_A | 1.112 | 0.88 | |
| 12_V | 68_P | 1.108 | 0.88 | |
| 238_E | 242_T | 1.108 | 0.88 | |
| 107_R | 213_H | 1.097 | 0.88 | |
| 111_F | 240_F | 1.089 | 0.87 | |
| 127_S | 188_K | 1.088 | 0.87 | |
| 117_L | 187_A | 1.088 | 0.87 | |
| 100_I | 120_L | 1.088 | 0.87 | |
| 179_V | 200_S | 1.07 | 0.86 | |
| 121_V | 190_V | 1.063 | 0.85 | |
| 117_L | 218_G | 1.056 | 0.85 | |
| 164_G | 168_S | 1.054 | 0.85 | |
| 8_P | 40_G | 1.041 | 0.84 | |
| 157_H | 180_N | 1.038 | 0.83 | |
| 100_I | 124_T | 1.036 | 0.83 | |
| 193_R | 211_I | 1.033 | 0.83 | |
| 159_V | 198_A | 1.031 | 0.83 | |
| 181_S | 202_D | 1.031 | 0.83 | |
| 59_L | 103_A | 1.03 | 0.83 | |
| 217_L | 236_L | 1.03 | 0.83 | |
| 110_I | 216_A | 1.027 | 0.82 | |
| 70_S | 96_S | 1.025 | 0.82 | |
| 11_G | 15_C | 1.025 | 0.82 | |
| 71_P | 74_V | 1.019 | 0.82 | |
| 221_W | 233_S | 1.011 | 0.81 | |
| 194_L | 210_V | 1.009 | 0.81 | |
| 195_R | 209_S | 1.008 | 0.81 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3fijA | 8 | 0.9488 | 100 | 0.34 | Contact Map | 0.861 |
| 1l9xA | 4 | 0.9094 | 100 | 0.434 | Contact Map | 0.55 |
| 3uowA | 2 | 0.8819 | 100 | 0.52 | Contact Map | 0.58 |
| 3nvaA | 2 | 0.8661 | 100 | 0.531 | Contact Map | 0.631 |
| 1s1mA | 2 | 0.8819 | 100 | 0.535 | Contact Map | 0.6 |
| 2w7tA | 1 | 0.878 | 100 | 0.535 | Contact Map | 0.589 |
| 1vcoA | 1 | 0.8858 | 100 | 0.548 | Contact Map | 0.585 |
| 1gpmA | 4 | 0.8031 | 100 | 0.55 | Contact Map | 0.727 |
| 3tqiA | 4 | 0.8031 | 100 | 0.554 | Contact Map | 0.715 |
| 2a9vA | 4 | 0.7913 | 100 | 0.558 | Contact Map | 0.693 |
Sequence Conservation (Image Generated using WebLogo v3)