| UniProt: | P75960 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13443 | ||
| Length: | 242 (230) | ||
| Sequences: | 2748 | ||
| Seq/Len: | 11.95 |
| NPD
Paralog alert: 0.16 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 17_E | 222_S | 3.852 | 1.00 | |
| 18_S | 70_N | 3.727 | 1.00 | |
| 78_K | 81_D | 2.67 | 1.00 | |
| 115_K | 149_H | 2.597 | 1.00 | |
| 99_E | 108_H | 2.553 | 1.00 | |
| 219_G | 224_V | 2.457 | 1.00 | |
| 14_I | 72_A | 2.441 | 1.00 | |
| 16_A | 22_T | 2.397 | 1.00 | |
| 88_L | 166_A | 2.182 | 1.00 | |
| 183_Y | 187_G | 2.177 | 1.00 | |
| 8_V | 76_L | 2.149 | 1.00 | |
| 71_A | 226_P | 2.149 | 1.00 | |
| 77_A | 81_D | 2.116 | 1.00 | |
| 118_C | 121_S | 2.088 | 1.00 | |
| 192_A | 197_A | 2.071 | 1.00 | |
| 137_C | 140_C | 2.055 | 1.00 | |
| 72_A | 225_V | 2.038 | 1.00 | |
| 76_L | 89_L | 2.026 | 1.00 | |
| 176_I | 221_A | 1.994 | 1.00 | |
| 183_Y | 186_A | 1.982 | 1.00 | |
| 5_R | 169_M | 1.954 | 1.00 | |
| 219_G | 223_Q | 1.896 | 1.00 | |
| 8_V | 174_I | 1.821 | 1.00 | |
| 42_E | 154_G | 1.809 | 1.00 | |
| 220_P | 223_Q | 1.786 | 1.00 | |
| 78_K | 82_A | 1.785 | 1.00 | |
| 80_Q | 105_N | 1.782 | 1.00 | |
| 125_L | 146_L | 1.774 | 1.00 | |
| 68_Q | 100_R | 1.735 | 1.00 | |
| 17_E | 220_P | 1.705 | 1.00 | |
| 80_Q | 103_N | 1.685 | 1.00 | |
| 99_E | 106_V | 1.676 | 1.00 | |
| 72_A | 221_A | 1.674 | 1.00 | |
| 167_L | 188_F | 1.668 | 1.00 | |
| 176_I | 202_L | 1.655 | 1.00 | |
| 118_C | 140_C | 1.616 | 1.00 | |
| 34_R | 37_D | 1.58 | 1.00 | |
| 75_A | 226_P | 1.573 | 1.00 | |
| 108_H | 112_E | 1.558 | 1.00 | |
| 80_Q | 104_T | 1.508 | 1.00 | |
| 7_L | 170_A | 1.498 | 1.00 | |
| 204_L | 220_P | 1.492 | 1.00 | |
| 55_Y | 58_R | 1.487 | 1.00 | |
| 123_Q | 138_H | 1.487 | 1.00 | |
| 123_Q | 139_C | 1.483 | 1.00 | |
| 193_K | 214_A | 1.48 | 1.00 | |
| 75_A | 225_V | 1.462 | 1.00 | |
| 124_V | 149_H | 1.454 | 1.00 | |
| 88_L | 107_I | 1.449 | 1.00 | |
| 103_N | 106_V | 1.441 | 1.00 | |
| 40_T | 43_G | 1.43 | 1.00 | |
| 165_M | 169_M | 1.426 | 1.00 | |
| 10_T | 14_I | 1.424 | 1.00 | |
| 10_T | 98_H | 1.415 | 1.00 | |
| 22_T | 25_A | 1.411 | 1.00 | |
| 5_R | 87_F | 1.389 | 0.99 | |
| 107_I | 162_E | 1.372 | 0.99 | |
| 107_I | 159_G | 1.371 | 0.99 | |
| 201_E | 210_G | 1.35 | 0.99 | |
| 227_E | 230_E | 1.343 | 0.99 | |
| 176_I | 225_V | 1.34 | 0.99 | |
| 75_A | 229_V | 1.34 | 0.99 | |
| 117_R | 149_H | 1.338 | 0.99 | |
| 41_P | 45_D | 1.336 | 0.99 | |
| 207_S | 210_G | 1.334 | 0.99 | |
| 30_W | 39_A | 1.315 | 0.99 | |
| 121_S | 140_C | 1.301 | 0.99 | |
| 116_V | 146_L | 1.28 | 0.99 | |
| 25_A | 31_E | 1.271 | 0.99 | |
| 117_R | 124_V | 1.268 | 0.99 | |
| 51_V | 55_Y | 1.263 | 0.99 | |
| 44_F | 119_S | 1.26 | 0.99 | |
| 77_A | 101_A | 1.253 | 0.99 | |
| 51_V | 152_W | 1.244 | 0.98 | |
| 167_L | 173_F | 1.239 | 0.98 | |
| 96_N | 108_H | 1.229 | 0.98 | |
| 162_E | 165_M | 1.225 | 0.98 | |
| 4_P | 171_D | 1.213 | 0.98 | |
| 79_L | 229_V | 1.213 | 0.98 | |
| 70_N | 222_S | 1.203 | 0.98 | |
| 75_A | 79_L | 1.197 | 0.98 | |
| 45_D | 119_S | 1.189 | 0.98 | |
| 44_F | 147_R | 1.188 | 0.98 | |
| 172_I | 200_V | 1.183 | 0.98 | |
| 78_K | 230_E | 1.182 | 0.98 | |
| 172_I | 198_H | 1.176 | 0.98 | |
| 5_R | 171_D | 1.166 | 0.97 | |
| 121_S | 137_C | 1.157 | 0.97 | |
| 198_H | 214_A | 1.15 | 0.97 | |
| 109_M | 163_I | 1.139 | 0.97 | |
| 202_L | 224_V | 1.13 | 0.97 | |
| 109_M | 185_A | 1.124 | 0.97 | |
| 68_Q | 74_L | 1.123 | 0.97 | |
| 175_A | 178_T | 1.122 | 0.97 | |
| 38_V | 43_G | 1.117 | 0.96 | |
| 112_E | 115_K | 1.113 | 0.96 | |
| 27_D | 31_E | 1.113 | 0.96 | |
| 39_A | 152_W | 1.11 | 0.96 | |
| 20_I | 67_I | 1.109 | 0.96 | |
| 83_L | 86_R | 1.103 | 0.96 | |
| 118_C | 137_C | 1.099 | 0.96 | |
| 71_A | 74_L | 1.092 | 0.96 | |
| 62_L | 67_I | 1.088 | 0.96 | |
| 89_L | 103_N | 1.086 | 0.96 | |
| 37_D | 50_L | 1.074 | 0.95 | |
| 12_A | 15_S | 1.073 | 0.95 | |
| 164_Y | 191_E | 1.062 | 0.95 | |
| 162_E | 166_A | 1.059 | 0.95 | |
| 76_L | 87_F | 1.051 | 0.94 | |
| 10_T | 76_L | 1.051 | 0.94 | |
| 210_G | 216_K | 1.051 | 0.94 | |
| 41_P | 155_E | 1.043 | 0.94 | |
| 7_L | 90_V | 1.041 | 0.94 | |
| 201_E | 213_F | 1.038 | 0.94 | |
| 180_G | 201_E | 1.032 | 0.94 | |
| 24_R | 28_G | 1.03 | 0.94 | |
| 226_P | 229_V | 1.03 | 0.94 | |
| 198_H | 215_E | 1.017 | 0.93 | |
| 43_G | 50_L | 1.016 | 0.93 | |
| 227_E | 231_K | 1.014 | 0.93 | |
| 160_M | 188_F | 1.009 | 0.93 | |
| 201_E | 207_S | 1.007 | 0.93 | |
| 96_N | 114_L | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1s5pA | 1 | 0.9587 | 100 | 0.125 | Contact Map | 0.784 |
| 1m2kA | 1 | 0.9711 | 100 | 0.132 | Contact Map | 0.835 |
| 1ma3A | 1 | 0.9628 | 100 | 0.132 | Contact Map | 0.792 |
| 1yc5A | 1 | 0.9463 | 100 | 0.139 | Contact Map | 0.852 |
| 3riyA | 2 | 0.9298 | 100 | 0.147 | Contact Map | 0.774 |
| 3u31A | 1 | 0.9669 | 100 | 0.152 | Contact Map | 0.743 |
| 4i5iA | 2 | 0.9711 | 100 | 0.176 | Contact Map | 0.786 |
| 4iaoA | 2 | 0.9711 | 100 | 0.185 | Contact Map | 0.756 |
| 4kxqA | 1 | 0.9669 | 100 | 0.187 | Contact Map | 0.787 |
| 2hjhA | 2 | 0.9711 | 100 | 0.188 | Contact Map | 0.758 |
Sequence Conservation (Image Generated using WebLogo v3)