| UniProt: | P75914 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13870 | ||
| Length: | 245 (233) | ||
| Sequences: | 1640 | ||
| Seq/Len: | 7.04 |
| YCDX
Paralog alert: 0.22 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 99_G | 130_S | 3.537 | 1.00 | |
| 21_S | 62_V | 3.376 | 1.00 | |
| 146_E | 183_A | 3.121 | 1.00 | |
| 97_I | 130_S | 3.113 | 1.00 | |
| 36_A | 95_L | 3.098 | 1.00 | |
| 26_Q | 30_K | 2.999 | 1.00 | |
| 26_Q | 29_Q | 2.789 | 1.00 | |
| 142_K | 179_A | 2.721 | 1.00 | |
| 35_F | 68_I | 2.572 | 1.00 | |
| 8_M | 35_F | 2.491 | 1.00 | |
| 109_D | 112_T | 2.483 | 1.00 | |
| 174_R | 211_A | 2.294 | 1.00 | |
| 145_A | 183_A | 2.168 | 1.00 | |
| 57_R | 70_R | 2.104 | 1.00 | |
| 38_T | 95_L | 2.031 | 1.00 | |
| 21_S | 25_A | 2.016 | 1.00 | |
| 122_A | 147_A | 2.015 | 1.00 | |
| 145_A | 179_A | 1.992 | 1.00 | |
| 55_N | 58_I | 1.945 | 1.00 | |
| 6_L | 36_A | 1.928 | 1.00 | |
| 198_T | 201_E | 1.906 | 1.00 | |
| 95_L | 128_I | 1.898 | 1.00 | |
| 98_A | 126_V | 1.893 | 1.00 | |
| 24_I | 66_V | 1.848 | 1.00 | |
| 118_I | 147_A | 1.803 | 1.00 | |
| 18_S | 22_D | 1.8 | 1.00 | |
| 10_T | 23_Y | 1.799 | 1.00 | |
| 187_V | 214_F | 1.776 | 1.00 | |
| 18_S | 196_A | 1.761 | 1.00 | |
| 122_A | 150_K | 1.751 | 1.00 | |
| 5_D | 191_S | 1.707 | 1.00 | |
| 179_A | 182_D | 1.702 | 1.00 | |
| 147_A | 150_K | 1.692 | 1.00 | |
| 179_A | 183_A | 1.676 | 1.00 | |
| 110_K | 138_E | 1.662 | 1.00 | |
| 56_M | 70_R | 1.647 | 1.00 | |
| 6_L | 34_L | 1.638 | 1.00 | |
| 28_K | 66_V | 1.632 | 1.00 | |
| 34_L | 69_L | 1.628 | 1.00 | |
| 67_G | 228_L | 1.616 | 1.00 | |
| 53_F | 70_R | 1.59 | 1.00 | |
| 141_V | 176_V | 1.588 | 1.00 | |
| 180_V | 185_G | 1.583 | 1.00 | |
| 121_I | 147_A | 1.583 | 1.00 | |
| 122_A | 151_H | 1.556 | 1.00 | |
| 108_H | 113_N | 1.524 | 0.99 | |
| 181_R | 214_F | 1.495 | 0.99 | |
| 3_P | 33_K | 1.479 | 0.99 | |
| 118_I | 144_V | 1.47 | 0.99 | |
| 20_L | 37_I | 1.461 | 0.99 | |
| 149_A | 185_G | 1.457 | 0.99 | |
| 12_A | 55_N | 1.445 | 0.99 | |
| 57_R | 60_P | 1.423 | 0.99 | |
| 118_I | 143_A | 1.402 | 0.99 | |
| 145_A | 176_V | 1.397 | 0.99 | |
| 181_R | 218_R | 1.385 | 0.99 | |
| 121_I | 148_A | 1.356 | 0.98 | |
| 147_A | 151_H | 1.335 | 0.98 | |
| 155_L | 180_V | 1.333 | 0.98 | |
| 34_L | 67_G | 1.309 | 0.98 | |
| 32_I | 200_G | 1.307 | 0.98 | |
| 121_I | 153_V | 1.303 | 0.98 | |
| 38_T | 71_G | 1.296 | 0.98 | |
| 207_K | 211_A | 1.294 | 0.98 | |
| 32_I | 202_F | 1.279 | 0.97 | |
| 132_P | 155_L | 1.272 | 0.97 | |
| 50_H | 92_S | 1.267 | 0.97 | |
| 20_L | 59_W | 1.262 | 0.97 | |
| 177_A | 214_F | 1.258 | 0.97 | |
| 24_I | 63_V | 1.256 | 0.97 | |
| 215_P | 218_R | 1.244 | 0.97 | |
| 15_H | 42_P | 1.244 | 0.97 | |
| 119_A | 122_A | 1.236 | 0.97 | |
| 145_A | 185_G | 1.233 | 0.97 | |
| 121_I | 144_V | 1.232 | 0.97 | |
| 159_N | 205_C | 1.221 | 0.96 | |
| 28_K | 65_G | 1.219 | 0.96 | |
| 22_D | 25_A | 1.211 | 0.96 | |
| 30_K | 199_M | 1.202 | 0.96 | |
| 121_I | 151_H | 1.202 | 0.96 | |
| 60_P | 66_V | 1.186 | 0.95 | |
| 8_M | 23_Y | 1.175 | 0.95 | |
| 118_I | 122_A | 1.169 | 0.95 | |
| 149_A | 183_A | 1.168 | 0.95 | |
| 195_T | 198_T | 1.163 | 0.95 | |
| 28_K | 63_V | 1.149 | 0.94 | |
| 149_A | 180_V | 1.143 | 0.94 | |
| 11_V | 19_T | 1.137 | 0.94 | |
| 157_I | 209_L | 1.119 | 0.93 | |
| 154_A | 220_L | 1.118 | 0.93 | |
| 19_T | 22_D | 1.109 | 0.93 | |
| 174_R | 212_V | 1.109 | 0.93 | |
| 51_W | 55_N | 1.104 | 0.93 | |
| 222_V | 226_R | 1.099 | 0.92 | |
| 193_S | 198_T | 1.075 | 0.91 | |
| 117_M | 144_V | 1.073 | 0.91 | |
| 59_W | 68_I | 1.068 | 0.91 | |
| 145_A | 180_V | 1.067 | 0.91 | |
| 87_G | 91_D | 1.067 | 0.91 | |
| 124_G | 153_V | 1.058 | 0.90 | |
| 229_N | 233_S | 1.058 | 0.90 | |
| 24_I | 68_I | 1.058 | 0.90 | |
| 41_G | 75_N | 1.058 | 0.90 | |
| 112_T | 115_Q | 1.056 | 0.90 | |
| 110_K | 140_D | 1.054 | 0.90 | |
| 206_L | 210_D | 1.051 | 0.90 | |
| 59_W | 63_V | 1.05 | 0.90 | |
| 177_A | 187_V | 1.038 | 0.89 | |
| 6_L | 227_L | 1.032 | 0.89 | |
| 226_R | 229_N | 1.025 | 0.88 | |
| 13_S | 39_D | 1.025 | 0.88 | |
| 38_T | 97_I | 1.024 | 0.88 | |
| 5_D | 8_M | 1.023 | 0.88 | |
| 25_A | 29_Q | 1.02 | 0.88 | |
| 6_L | 69_L | 1.02 | 0.88 | |
| 24_I | 59_W | 1.017 | 0.88 | |
| 146_E | 150_K | 1.007 | 0.87 | |
| 154_A | 230_F | 1.003 | 0.87 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1m65A | 1 | 1 | 100 | 0.351 | Contact Map | 0.745 |
| 4gc3A | 1 | 0.9551 | 100 | 0.397 | Contact Map | 0.789 |
| 3b0xA | 1 | 0.9265 | 100 | 0.399 | Contact Map | 0.828 |
| 2w9mA | 2 | 0.9469 | 100 | 0.407 | Contact Map | 0.646 |
| 3dcpA | 3 | 0.8694 | 100 | 0.414 | Contact Map | 0.871 |
| 2yxoA | 2 | 0.9347 | 100 | 0.427 | Contact Map | 0.773 |
| 3qy7A | 1 | 0.9592 | 100 | 0.514 | Contact Map | 0.418 |
| 2wjeA | 1 | 0.9347 | 100 | 0.515 | Contact Map | 0.444 |
| 1v77A | 1 | 0.8327 | 100 | 0.522 | Contact Map | 0.53 |
| 2anuA | 6 | 0.8204 | 100 | 0.593 | Contact Map | 0.656 |
Sequence Conservation (Image Generated using WebLogo v3)