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YCCU - Uncharacterized protein YccU
UniProt: P75874 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13723
Length: 137 (134)
Sequences: 896
Seq/Len: 6.69

YCCU
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
63_T 66_D 3.353 1.00
88_Q 112_L 3.143 1.00
62_G 66_D 2.608 1.00
35_Y 130_I 2.599 1.00
42_H 58_Q 2.585 1.00
37_L 58_Q 2.417 1.00
87_A 98_L 2.389 1.00
67_V 71_V 2.241 1.00
15_T 42_H 2.117 1.00
102_L 128_I 2.11 1.00
111_V 115_D 2.06 1.00
61_Y 68_P 2.05 1.00
24_K 27_R 1.83 1.00
34_K 38_D 1.824 1.00
42_H 69_E 1.814 1.00
84_W 106_N 1.812 1.00
21_A 33_M 1.781 1.00
65_A 89_E 1.778 1.00
87_A 109_A 1.763 1.00
7_A 11_T 1.709 1.00
13_T 73_M 1.688 1.00
65_A 92_A 1.604 1.00
8_G 12_S 1.601 1.00
83_A 100_M 1.581 1.00
111_V 114_R 1.54 0.99
55_L 60_G 1.538 0.99
9_I 97_T 1.509 0.99
13_T 97_T 1.47 0.99
76_V 100_M 1.466 0.99
3_E 132_R 1.439 0.99
44_I 69_E 1.435 0.99
73_M 126_P 1.432 0.99
110_A 120_V 1.373 0.98
64_L 93_I 1.329 0.98
54_T 59_K 1.329 0.98
46_V 67_V 1.322 0.98
110_A 122_M 1.289 0.97
91_I 112_L 1.279 0.97
15_T 69_E 1.266 0.97
91_I 116_A 1.262 0.97
16_I 126_P 1.253 0.97
50_V 55_L 1.237 0.96
37_L 56_L 1.236 0.96
37_L 43_V 1.221 0.96
105_I 123_D 1.211 0.96
22_S 29_S 1.2 0.95
23_D 50_V 1.191 0.95
19_V 74_V 1.175 0.95
70_K 96_K 1.161 0.94
84_W 112_L 1.137 0.93
79_N 82_A 1.126 0.93
31_R 127_A 1.122 0.93
124_R 129_E 1.121 0.93
129_E 132_R 1.112 0.92
70_K 93_I 1.095 0.92
75_D 126_P 1.095 0.92
76_V 98_L 1.09 0.91
85_G 88_Q 1.076 0.91
96_K 119_N 1.065 0.90
97_T 119_N 1.051 0.89
19_V 90_A 1.051 0.89
84_W 88_Q 1.046 0.89
95_A 118_L 1.045 0.89
87_A 113_A 1.044 0.89
16_I 73_M 1.041 0.89
30_Y 56_L 1.027 0.88
3_E 133_L 1.001 0.86
82_A 85_G 1 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ff4A10.890599.90.446Contact Map0.507
2csuA20.941699.90.503Contact Map0.66
2duwA1199.90.519Contact Map0.643
1iukA1199.90.536Contact Map0.743
2d59A10.985499.80.574Contact Map0.875
1y81A10.985499.80.577Contact Map0.655
3pffA10.948999.70.621Contact Map0.33
2fp4A10.978199.60.65Contact Map0.417
2yv1A10.978199.50.657Contact Map0.494
2yv2A10.978199.40.676Contact Map0.541

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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