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OPENSEQ.org
YCAQ - Uncharacterized protein YcaQ
UniProt: P75843 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13701
Length: 410 (404)
Sequences: 417
Seq/Len: 1.03
YCAQ
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
302_E 308_S 2.976 1.00
186_D 190_R 2.903 1.00
242_R 251_I 2.514 0.99
213_D 250_Q 2.214 0.98
96_D 214_N 2.168 0.98
130_I 172_K 2.136 0.97
344_H 351_E 2.006 0.96
302_E 310_R 1.99 0.96
133_I 173_V 1.985 0.95
51_I 342_K 1.92 0.94
55_S 293_P 1.908 0.94
132_H 136_K 1.877 0.93
55_S 58_L 1.846 0.93
293_P 311_L 1.832 0.92
49_I 313_C 1.796 0.91
38_I 81_L 1.76 0.90
117_A 121_E 1.736 0.89
48_T 325_F 1.727 0.89
329_L 371_L 1.723 0.89
192_M 196_D 1.712 0.88
39_S 95_S 1.703 0.88
55_S 311_L 1.699 0.88
177_E 184_V 1.672 0.87
372_R 400_C 1.666 0.87
84_Y 104_M 1.665 0.86
338_R 358_Q 1.633 0.85
82_M 97_F 1.577 0.82
55_S 296_W 1.576 0.82
53_A 57_Y 1.576 0.82
313_C 325_F 1.536 0.80
294_V 301_A 1.534 0.80
48_T 313_C 1.492 0.77
133_I 139_V 1.487 0.77
127_A 172_K 1.485 0.77
222_F 227_L 1.472 0.76
51_I 138_P 1.469 0.75
329_L 355_L 1.455 0.74
46_I 91_F 1.44 0.73
167_L 193_P 1.439 0.73
46_I 327_L 1.437 0.73
209_I 244_A 1.432 0.73
41_M 180_N 1.43 0.73
7_S 10_D 1.423 0.72
216_A 227_L 1.407 0.71
188_T 212_L 1.397 0.70
209_I 248_Q 1.385 0.69
331_H 370_G 1.373 0.68
210_I 213_D 1.368 0.68
295_V 301_A 1.366 0.68
179_R 184_V 1.362 0.67
212_L 241_W 1.354 0.67
58_L 311_L 1.352 0.66
85_W 340_D 1.351 0.66
133_I 186_D 1.349 0.66
173_V 308_S 1.339 0.65
44_L 60_L 1.338 0.65
287_V 339_M 1.329 0.64
371_L 375_I 1.321 0.64
8_L 304_L 1.32 0.64
137_G 186_D 1.317 0.63
50_N 337_G 1.316 0.63
224_E 228_A 1.313 0.63
11_A 256_V 1.305 0.62
343_M 384_A 1.304 0.62
55_S 315_T 1.298 0.62
6_L 10_D 1.291 0.61
252_I 267_D 1.288 0.61
203_S 206_E 1.281 0.60
14_L 335_L 1.281 0.60
153_G 156_E 1.279 0.60
130_I 167_L 1.278 0.60
205_T 239_A 1.271 0.59
288_L 335_L 1.269 0.59
267_D 402_T 1.266 0.59
86_A 96_D 1.266 0.59
206_E 255_H 1.265 0.59
376_T 380_N 1.258 0.58
226_W 303_Q 1.256 0.58
291_F 311_L 1.254 0.58
129_L 294_V 1.22 0.55
271_L 274_R 1.213 0.54
17_A 20_G 1.211 0.54
199_R 336_V 1.207 0.54
92_M 100_I 1.206 0.53
61_F 81_L 1.206 0.53
291_F 300_R 1.206 0.53
53_A 69_A 1.196 0.52
89_A 181_F 1.191 0.52
307_F 358_Q 1.19 0.52
374_A 377_D 1.189 0.52
257_E 403_G 1.188 0.52
91_F 98_R 1.186 0.52
101_R 104_M 1.178 0.51
307_F 335_L 1.169 0.50
67_Y 72_L 1.168 0.50
217_R 253_A 1.168 0.50
155_W 165_E 1.162 0.49
183_R 232_R 1.158 0.49
90_C 182_Q 1.156 0.49
349_I 388_T 1.154 0.49
105_L 204_Q 1.152 0.48
48_T 181_F 1.15 0.48
155_W 291_F 1.149 0.48
128_Q 131_Q 1.148 0.48
96_D 374_A 1.141 0.47
87_H 291_F 1.137 0.47
124_A 236_P 1.137 0.47
352_V 379_A 1.131 0.46
397_F 403_G 1.13 0.46
56_P 226_W 1.129 0.46
55_S 291_F 1.128 0.46
204_Q 237_A 1.123 0.46
307_F 338_R 1.123 0.46
64_L 183_R 1.122 0.46
132_H 164_L 1.118 0.45
89_A 155_W 1.117 0.45
92_M 133_I 1.115 0.45
164_L 327_L 1.114 0.45
156_E 175_V 1.114 0.45
144_F 311_L 1.111 0.45
319_K 376_T 1.107 0.44
89_A 165_E 1.106 0.44
221_I 262_L 1.104 0.44
131_Q 135_D 1.102 0.44
285_S 370_G 1.101 0.44
229_D 232_R 1.1 0.44
79_G 329_L 1.099 0.43
206_E 269_L 1.097 0.43
339_M 352_V 1.096 0.43
39_S 188_T 1.095 0.43
90_C 297_D 1.094 0.43
246_A 253_A 1.094 0.43
65_G 381_W 1.093 0.43
140_R 317_A 1.09 0.43
139_V 144_F 1.089 0.43
146_H 160_H 1.086 0.42
138_P 167_L 1.085 0.42
52_V 297_D 1.084 0.42
85_W 165_E 1.083 0.42
229_D 381_W 1.08 0.42
246_A 251_I 1.08 0.42
90_C 296_W 1.08 0.42
246_A 263_W 1.079 0.42
88_E 314_Y 1.078 0.42
16_L 315_T 1.075 0.41
395_G 398_T 1.074 0.41
62_S 170_A 1.072 0.41
48_T 291_F 1.072 0.41
65_G 229_D 1.071 0.41
344_H 347_T 1.069 0.41
213_D 245_R 1.069 0.41
31_L 74_E 1.069 0.41
57_Y 170_A 1.067 0.41
22_L 337_G 1.065 0.40
9_A 281_T 1.065 0.40
82_M 86_A 1.064 0.40
12_R 18_A 1.063 0.40
42_S 93_P 1.059 0.40
140_R 184_V 1.056 0.40
329_L 337_G 1.054 0.39
397_F 401_R 1.054 0.39
318_P 322_Y 1.053 0.39
394_Q 400_C 1.049 0.39
263_W 382_Q 1.046 0.39
178_R 193_P 1.046 0.39
222_F 332_R 1.045 0.39
288_L 330_L 1.045 0.39
213_D 401_R 1.045 0.39
322_Y 338_R 1.043 0.38
23_N 37_T 1.043 0.38
90_C 374_A 1.042 0.38
181_F 191_V 1.038 0.38
19_Q 85_W 1.036 0.38
48_T 87_H 1.035 0.38
206_E 236_P 1.034 0.38
95_S 251_I 1.034 0.38
42_S 163_H 1.033 0.38
138_P 342_K 1.032 0.37
168_F 218_S 1.031 0.37
48_T 222_F 1.026 0.37
230_Y 381_W 1.024 0.37
192_M 198_E 1.023 0.37
218_S 245_R 1.022 0.37
301_A 311_L 1.016 0.36
41_M 150_G 1.014 0.36
98_R 303_Q 1.014 0.36
89_A 291_F 1.014 0.36
229_D 295_V 1.013 0.36
89_A 161_K 1.011 0.36
204_Q 208_E 1.007 0.35
331_H 336_V 1.007 0.35
82_M 163_H 1.007 0.35
104_M 168_F 1.006 0.35
87_H 300_R 1.006 0.35
14_L 291_F 1.004 0.35
49_I 324_Y 1.004 0.35
337_G 344_H 1.001 0.35
181_F 291_F 1.001 0.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2htjA10.195151.30.974Contact Map0.601
4kmfA10.151251.10.974Contact Map0.611
1qgpA10.180548.80.974Contact Map0.608
1qbjA30.185448.30.974Contact Map0.712
3eyiA20.168340.70.975Contact Map0.676
1sfuA20.175636.10.976Contact Map0.645
2lnbA10.1927340.976Contact Map0.583
2heoA20.16133.40.976Contact Map0.843
1xmkA10.187831.80.977Contact Map0.498
2fu4A20.195130.70.977Contact Map0.594
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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