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OPENSEQ.org
YBGL - UPF0271 protein YbgL
UniProt: P75746 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13308
Length: 244 (243)
Sequences: 981
Seq/Len: 4.04
YBGL
Paralog alert: 0.09 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
167_A 204_T 3.134 1.00
48_I 98_G 2.843 1.00
21_T 50_N 2.603 1.00
167_A 206_E 2.563 1.00
38_Q 80_A 2.561 1.00
90_A 94_R 2.505 1.00
137_V 214_T 2.393 1.00
60_F 112_Q 2.387 1.00
61_P 71_M 2.332 1.00
202_S 206_E 2.314 1.00
24_S 242_V 2.235 1.00
193_E 207_W 2.218 1.00
65_N 69_S 2.163 1.00
164_G 178_G 2.158 1.00
167_A 202_S 2.15 1.00
87_G 91_T 2.112 1.00
135_I 156_R 2.031 1.00
166_Q 173_P 2.011 1.00
12_G 39_I 2.009 1.00
199_R 207_W 1.983 1.00
164_G 172_V 1.963 1.00
20_L 23_V 1.948 1.00
44_V 92_I 1.919 1.00
193_E 197_H 1.915 1.00
121_D 150_Q 1.909 1.00
83_L 130_C 1.888 1.00
164_G 180_L 1.842 1.00
40_M 89_L 1.821 1.00
41_Q 80_A 1.807 1.00
45_R 96_Q 1.801 1.00
32_F 84_Y 1.787 0.99
79_Y 129_A 1.785 0.99
138_G 155_T 1.764 0.99
191_T 215_V 1.759 0.99
193_E 199_R 1.753 0.99
41_Q 96_Q 1.751 0.99
187_A 227_F 1.736 0.99
54_I 98_G 1.734 0.99
70_A 112_Q 1.709 0.99
117_A 143_E 1.688 0.99
90_A 130_C 1.678 0.99
159_V 212_A 1.672 0.99
79_Y 125_R 1.646 0.99
113_A 123_I 1.626 0.99
138_G 145_I 1.599 0.99
84_Y 88_A 1.571 0.98
164_G 203_I 1.567 0.98
4_D 24_S 1.546 0.98
143_E 146_R 1.493 0.98
202_S 208_A 1.476 0.97
4_D 25_S 1.472 0.97
64_E 81_Q 1.468 0.97
124_A 147_A 1.455 0.97
217_L 228_A 1.455 0.97
164_G 190_Q 1.452 0.97
86_I 130_C 1.414 0.96
41_Q 45_R 1.399 0.96
166_Q 176_Q 1.383 0.96
158_E 216_C 1.38 0.96
173_P 176_Q 1.371 0.95
44_V 93_A 1.364 0.95
181_I 187_A 1.353 0.95
184_E 188_L 1.348 0.95
78_V 119_L 1.331 0.94
93_A 98_G 1.312 0.94
201_K 207_W 1.301 0.93
104_K 216_C 1.301 0.93
23_V 26_A 1.295 0.93
125_R 129_A 1.288 0.93
44_V 89_L 1.283 0.93
166_Q 170_S 1.279 0.93
12_G 43_C 1.276 0.92
84_Y 87_G 1.265 0.92
185_E 230_R 1.259 0.92
104_K 158_E 1.257 0.92
192_L 234_A 1.256 0.92
15_S 18_E 1.25 0.91
200_V 208_A 1.247 0.91
166_Q 172_V 1.23 0.91
46_E 49_K 1.204 0.89
234_A 238_K 1.204 0.89
124_A 148_G 1.201 0.89
156_R 213_Q 1.201 0.89
86_I 103_V 1.194 0.89
70_A 116_E 1.184 0.88
70_A 115_K 1.177 0.88
115_K 170_S 1.175 0.88
189_A 234_A 1.172 0.87
122_A 126_A 1.168 0.87
172_V 203_I 1.16 0.87
226_A 229_R 1.158 0.87
32_F 81_Q 1.15 0.86
104_K 110_Y 1.135 0.85
20_L 50_N 1.119 0.84
163_R 174_R 1.117 0.84
145_I 157_E 1.11 0.83
192_L 196_Q 1.095 0.82
140_A 157_E 1.093 0.82
9_L 20_L 1.09 0.82
121_D 125_R 1.088 0.82
121_D 151_Y 1.083 0.81
103_V 127_V 1.083 0.81
102_H 137_V 1.08 0.81
159_V 194_M 1.075 0.81
73_L 81_Q 1.074 0.80
121_D 147_A 1.07 0.80
184_E 230_R 1.066 0.80
199_R 209_T 1.055 0.79
17_A 46_E 1.051 0.78
193_E 201_K 1.051 0.78
73_L 78_V 1.05 0.78
145_I 155_T 1.045 0.78
196_Q 238_K 1.042 0.78
78_V 122_A 1.035 0.77
232_R 236_A 1.035 0.77
172_V 190_Q 1.027 0.76
236_A 242_V 1.019 0.75
112_Q 119_L 1.018 0.75
53_A 102_H 1.007 0.74
124_A 153_L 1.007 0.74
76_E 80_A 1.005 0.74
180_L 221_G 1.002 0.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1xw8A11100-0.007Contact Map0.745
1v6tA11100-0.005Contact Map0.843
2dfaA11100-0.004Contact Map0.771
2x5eA10.97541000.02Contact Map0.717
2i5iA20.87794.30.941Contact Map0.529
2vyoA10.737784.40.953Contact Map0.433
2qv5A20.815672.70.958Contact Map0.385
1ny1A20.713171.80.958Contact Map0.512
2j13A10.717256.30.962Contact Map0.516
1vl2A40.9303530.963Contact Map0.207
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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