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OPENSEQ.org

YAGP - Uncharacterized protein YagP
UniProt: P75684 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13555
Length: 136 (123)
Sequences: 10076
Seq/Len: 81.92

YAGP
Paralog alert: 0.90 [within 20: 0.34] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
70_A 77_T 4.381 1.00
26_K 57_Q 3.846 1.00
71_L 87_Y 3.816 1.00
95_S 98_D 3.603 1.00
67_L 87_Y 3.579 1.00
15_E 94_V 3.358 1.00
87_Y 92_K 2.881 1.00
13_R 26_K 2.85 1.00
109_L 125_I 2.622 1.00
17_F 21_G 2.41 1.00
85_R 89_E 2.377 1.00
28_I 66_M 2.321 1.00
19_A 100_F 2.292 1.00
67_L 71_L 2.282 1.00
18_L 21_G 2.252 1.00
27_C 41_W 2.067 1.00
71_L 92_K 2.066 1.00
25_H 76_I 1.983 1.00
10_A 15_E 1.864 1.00
58_I 69_L 1.824 1.00
60_T 66_M 1.813 1.00
86_P 90_S 1.786 1.00
87_Y 90_S 1.73 1.00
79_A 84_F 1.66 1.00
81_Q 85_R 1.653 1.00
126_D 129_K 1.62 1.00
27_C 54_I 1.61 1.00
68_R 72_A 1.472 1.00
124_L 128_V 1.456 1.00
127_Y 131_W 1.452 1.00
76_I 96_L 1.434 1.00
122_R 126_D 1.379 0.99
69_L 74_G 1.354 0.99
21_G 24_T 1.303 0.99
40_R 51_D 1.291 0.99
117_I 122_R 1.276 0.99
70_A 93_L 1.249 0.99
10_A 96_L 1.222 0.98
84_F 87_Y 1.21 0.98
29_G 56_P 1.173 0.98
123_A 127_Y 1.173 0.98
60_T 65_L 1.17 0.97
84_F 88_I 1.152 0.97
28_I 75_G 1.138 0.97
95_S 101_L 1.138 0.97
63_L 80_T 1.12 0.96
111_F 125_I 1.116 0.96
86_P 89_E 1.11 0.96
80_T 83_T 1.108 0.96
117_I 121_L 1.094 0.96
88_I 95_S 1.092 0.96
26_K 56_P 1.091 0.96
13_R 25_H 1.084 0.96
119_P 123_A 1.077 0.95
66_M 77_T 1.07 0.95
45_E 48_R 1.039 0.94
123_A 126_D 1.031 0.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3hhgA80.977999.30.395Contact Map0.875
3mz1A40.992699.30.406Contact Map0.654
3szpA20.948599.20.421Contact Map0.873
1al3A10.970699.10.449Contact Map0.632
3fzvA40.963299.10.457Contact Map0.627
3hhfB20.977999.10.46Contact Map0.826
3kosA10.970699.10.461Contact Map0.731
2hxrA20.955999.10.462Contact Map0.726
4ab5A20.955999.10.463Contact Map0.73
3fd3A10.9412990.465Contact Map0.65

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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