| UniProt: | P69789 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | |||
| Length: | 161 (148) | ||
| Sequences: | 869 | ||
| Seq/Len: | 5.87 |
| PTXB
Paralog alert: 0.77 [within 20: 0.02] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 28_R | 32_L | 3.917 | 1.00 | |
| 109_D | 122_R | 3.86 | 1.00 | |
| 87_S | 101_H | 3.193 | 1.00 | |
| 91_N | 135_V | 2.674 | 1.00 | |
| 89_I | 146_I | 2.666 | 1.00 | |
| 77_L | 142_L | 2.385 | 1.00 | |
| 22_L | 26_V | 2.207 | 1.00 | |
| 17_L | 21_L | 2.154 | 1.00 | |
| 139_R | 143_D | 1.999 | 1.00 | |
| 131_I | 135_V | 1.974 | 1.00 | |
| 13_I | 17_L | 1.967 | 1.00 | |
| 30_L | 34_F | 1.93 | 1.00 | |
| 76_I | 131_I | 1.923 | 1.00 | |
| 121_F | 130_I | 1.923 | 1.00 | |
| 37_C | 43_D | 1.897 | 1.00 | |
| 38_T | 41_R | 1.712 | 1.00 | |
| 17_L | 20_T | 1.688 | 1.00 | |
| 77_L | 145_L | 1.686 | 1.00 | |
| 79_A | 111_V | 1.685 | 1.00 | |
| 109_D | 113_K | 1.642 | 1.00 | |
| 102_D | 105_Q | 1.591 | 0.99 | |
| 79_A | 115_L | 1.547 | 0.99 | |
| 80_L | 129_V | 1.517 | 0.99 | |
| 31_I | 38_T | 1.485 | 0.99 | |
| 89_I | 142_L | 1.484 | 0.99 | |
| 103_M | 127_I | 1.432 | 0.98 | |
| 88_S | 99_A | 1.41 | 0.98 | |
| 31_I | 41_R | 1.389 | 0.98 | |
| 108_D | 111_V | 1.374 | 0.98 | |
| 136_S | 140_E | 1.373 | 0.98 | |
| 75_G | 115_L | 1.368 | 0.98 | |
| 6_A | 9_M | 1.349 | 0.97 | |
| 91_N | 139_R | 1.329 | 0.97 | |
| 93_A | 133_L | 1.322 | 0.97 | |
| 77_L | 146_I | 1.309 | 0.97 | |
| 91_N | 115_L | 1.293 | 0.97 | |
| 24_F | 28_R | 1.277 | 0.96 | |
| 73_A | 141_Q | 1.267 | 0.96 | |
| 25_V | 29_T | 1.257 | 0.96 | |
| 137_Q | 140_E | 1.228 | 0.95 | |
| 29_T | 33_Q | 1.224 | 0.95 | |
| 50_S | 53_E | 1.198 | 0.94 | |
| 98_I | 142_L | 1.197 | 0.94 | |
| 111_V | 114_K | 1.195 | 0.94 | |
| 129_V | 135_V | 1.195 | 0.94 | |
| 14_A | 18_C | 1.19 | 0.94 | |
| 37_C | 42_E | 1.182 | 0.93 | |
| 91_N | 136_S | 1.177 | 0.93 | |
| 24_F | 32_L | 1.171 | 0.93 | |
| 47_K | 51_K | 1.149 | 0.92 | |
| 21_L | 25_V | 1.147 | 0.92 | |
| 51_K | 54_Y | 1.128 | 0.91 | |
| 91_N | 138_L | 1.126 | 0.91 | |
| 98_I | 129_V | 1.125 | 0.91 | |
| 115_L | 135_V | 1.118 | 0.91 | |
| 26_V | 30_L | 1.115 | 0.91 | |
| 129_V | 138_L | 1.109 | 0.90 | |
| 3_S | 6_A | 1.1 | 0.90 | |
| 87_S | 99_A | 1.092 | 0.89 | |
| 18_C | 26_V | 1.087 | 0.89 | |
| 99_A | 126_A | 1.069 | 0.88 | |
| 103_M | 125_D | 1.066 | 0.88 | |
| 135_V | 138_L | 1.04 | 0.86 | |
| 90_N | 93_A | 1.036 | 0.86 | |
| 47_K | 54_Y | 1.035 | 0.86 | |
| 93_A | 134_H | 1.023 | 0.85 | |
| 112_F | 117_A | 1.015 | 0.84 | |
| 90_N | 139_R | 1.013 | 0.84 | |
| 48_L | 51_K | 1.006 | 0.83 | |
| 25_V | 28_R | 1.001 | 0.83 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3bp3A | 2 | 0.5093 | 99.9 | 0.566 | Contact Map | 0.733 |
| 1ibaA | 1 | 0.6211 | 99.9 | 0.574 | Contact Map | 0.22 |
| 3ipjA | 2 | 0.5528 | 99.9 | 0.596 | Contact Map | 0.713 |
| 3qnqA | 4 | 0.3354 | 81.8 | 0.916 | Contact Map | 0.557 |
| 1ldfA | 1 | 0.354 | 17.7 | 0.947 | Contact Map | 0.435 |
| 3hd7A | 2 | 0.1988 | 6.5 | 0.956 | Contact Map | 0.62 |
| 2kncA | 1 | 0.3043 | 6.3 | 0.957 | Contact Map | 0.485 |
| 3arcI | 2 | 0.236 | 5.9 | 0.957 | Contact Map | 0.599 |
| 1mhsA | 2 | 0.4099 | 4.5 | 0.96 | Contact Map | 0.197 |
| 3lw5I | 1 | 0.1863 | 4.1 | 0.961 | Contact Map | 0.398 |
Sequence Conservation (Image Generated using WebLogo v3)