| UniProt: | P69441 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10032 | ||
| Length: | 214 (209) | ||
| Sequences: | 2890 | ||
| Seq/Len: | 13.83 |
| KAD
Paralog alert: 0.08 [within 20: 0.02] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 113_D | 172_H | 3.293 | 1.00 | |
| 23_K | 210_E | 2.781 | 1.00 | |
| 35_L | 64_V | 2.743 | 1.00 | |
| 115_L | 118_D | 2.728 | 1.00 | |
| 50_K | 54_D | 2.718 | 1.00 | |
| 52_I | 60_T | 2.687 | 1.00 | |
| 200_K | 208_D | 2.624 | 1.00 | |
| 169_V | 173_Q | 2.511 | 1.00 | |
| 110_D | 195_K | 2.379 | 1.00 | |
| 65_I | 86_F | 2.362 | 1.00 | |
| 48_Q | 51_D | 2.309 | 1.00 | |
| 71_R | 76_D | 2.274 | 1.00 | |
| 97_K | 185_E | 2.224 | 1.00 | |
| 183_S | 195_K | 2.222 | 1.00 | |
| 118_D | 136_K | 2.221 | 1.00 | |
| 109_F | 198_G | 2.22 | 1.00 | |
| 120_I | 164_V | 2.205 | 1.00 | |
| 38_A | 70_E | 2.184 | 1.00 | |
| 37_A | 41_S | 2.134 | 1.00 | |
| 19_F | 206_R | 2.124 | 1.00 | |
| 200_K | 204_E | 2.11 | 1.00 | |
| 23_K | 206_R | 2.037 | 1.00 | |
| 44_E | 48_Q | 2.027 | 1.00 | |
| 39_V | 53_M | 1.995 | 1.00 | |
| 69_K | 98_E | 1.994 | 1.00 | |
| 170_E | 174_M | 1.966 | 1.00 | |
| 112_P | 199_T | 1.946 | 1.00 | |
| 126_H | 129_S | 1.936 | 1.00 | |
| 157_K | 160_Q | 1.936 | 1.00 | |
| 44_E | 47_K | 1.863 | 1.00 | |
| 24_Y | 210_E | 1.857 | 1.00 | |
| 108_E | 195_K | 1.844 | 1.00 | |
| 19_F | 203_A | 1.807 | 1.00 | |
| 127_A | 154_T | 1.804 | 1.00 | |
| 117_V | 165_R | 1.78 | 1.00 | |
| 161_E | 165_R | 1.741 | 1.00 | |
| 51_D | 55_A | 1.717 | 1.00 | |
| 201_P | 204_E | 1.635 | 1.00 | |
| 111_V | 198_G | 1.631 | 1.00 | |
| 124_R | 135_V | 1.626 | 1.00 | |
| 194_A | 212_I | 1.607 | 1.00 | |
| 65_I | 95_A | 1.6 | 1.00 | |
| 105_Y | 194_A | 1.595 | 1.00 | |
| 38_A | 43_S | 1.595 | 1.00 | |
| 60_T | 63_L | 1.574 | 1.00 | |
| 176_A | 180_G | 1.541 | 1.00 | |
| 160_Q | 163_T | 1.505 | 1.00 | |
| 142_V | 145_K | 1.504 | 1.00 | |
| 122_G | 125_V | 1.496 | 1.00 | |
| 42_G | 47_K | 1.494 | 1.00 | |
| 6_L | 179_I | 1.488 | 1.00 | |
| 122_G | 134_H | 1.468 | 1.00 | |
| 204_E | 208_D | 1.445 | 1.00 | |
| 145_K | 152_E | 1.444 | 1.00 | |
| 48_Q | 66_A | 1.432 | 1.00 | |
| 146_D | 149_T | 1.427 | 1.00 | |
| 27_P | 71_R | 1.419 | 1.00 | |
| 73_A | 99_A | 1.414 | 1.00 | |
| 16_Q | 209_L | 1.394 | 0.99 | |
| 166_K | 169_V | 1.377 | 0.99 | |
| 126_H | 149_T | 1.376 | 0.99 | |
| 129_S | 146_D | 1.357 | 0.99 | |
| 129_S | 149_T | 1.356 | 0.99 | |
| 126_H | 146_D | 1.339 | 0.99 | |
| 180_G | 183_S | 1.334 | 0.99 | |
| 38_A | 67_L | 1.321 | 0.99 | |
| 8_A | 171_Y | 1.316 | 0.99 | |
| 63_L | 66_A | 1.312 | 0.99 | |
| 75_E | 78_R | 1.312 | 0.99 | |
| 97_K | 181_Y | 1.302 | 0.99 | |
| 115_L | 199_T | 1.288 | 0.99 | |
| 71_R | 74_Q | 1.276 | 0.99 | |
| 127_A | 151_E | 1.259 | 0.99 | |
| 180_G | 184_K | 1.256 | 0.99 | |
| 128_P | 149_T | 1.245 | 0.98 | |
| 200_K | 205_V | 1.231 | 0.98 | |
| 106_V | 193_Y | 1.231 | 0.98 | |
| 52_I | 57_K | 1.23 | 0.98 | |
| 32_G | 36_R | 1.22 | 0.98 | |
| 172_H | 176_A | 1.184 | 0.98 | |
| 107_L | 209_L | 1.152 | 0.97 | |
| 102_N | 192_K | 1.142 | 0.97 | |
| 19_F | 22_E | 1.14 | 0.97 | |
| 197_D | 200_K | 1.138 | 0.97 | |
| 69_K | 99_A | 1.125 | 0.97 | |
| 91_P | 94_D | 1.123 | 0.97 | |
| 204_E | 207_A | 1.123 | 0.97 | |
| 69_K | 73_A | 1.113 | 0.96 | |
| 127_A | 152_E | 1.108 | 0.96 | |
| 94_D | 97_K | 1.107 | 0.96 | |
| 207_A | 211_K | 1.09 | 0.96 | |
| 43_S | 46_G | 1.079 | 0.95 | |
| 166_K | 170_E | 1.067 | 0.95 | |
| 57_K | 166_K | 1.063 | 0.95 | |
| 196_V | 212_I | 1.063 | 0.95 | |
| 208_D | 211_K | 1.061 | 0.95 | |
| 51_D | 54_D | 1.054 | 0.95 | |
| 171_Y | 175_T | 1.047 | 0.94 | |
| 121_V | 161_E | 1.033 | 0.94 | |
| 61_D | 89_T | 1.025 | 0.93 | |
| 108_E | 179_I | 1.015 | 0.93 | |
| 49_A | 53_M | 1.011 | 0.93 | |
| 11_A | 111_V | 1.006 | 0.93 | |
| 109_F | 209_L | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1e4vA | 2 | 1 | 100 | 0.36 | Contact Map | 0.759 |
| 3gmtA | 2 | 1 | 100 | 0.366 | Contact Map | 0.694 |
| 3be4A | 1 | 0.972 | 100 | 0.381 | Contact Map | 0.703 |
| 2xb4A | 1 | 0.972 | 100 | 0.384 | Contact Map | 0.639 |
| 3tlxA | 4 | 0.9766 | 100 | 0.391 | Contact Map | 0.663 |
| 3fb4A | 1 | 0.9766 | 100 | 0.396 | Contact Map | 0.808 |
| 3dl0A | 2 | 0.9766 | 100 | 0.399 | Contact Map | 0.75 |
| 1ak2A | 1 | 0.9766 | 100 | 0.401 | Contact Map | 0.665 |
| 1akyA | 1 | 0.9766 | 100 | 0.401 | Contact Map | 0.658 |
| 1zd8A | 1 | 0.9626 | 100 | 0.408 | Contact Map | 0.699 |
Sequence Conservation (Image Generated using WebLogo v3)