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OPENSEQ.org

RS21 - 30S ribosomal protein S21
UniProt: P68679 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10920
Length: 71 (66)
Sequences: 525
Seq/Len: 7.95

RS21
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
39_E 47_R 3.117 1.00
31_E 35_R 2.699 1.00
61_A 64_N 1.571 1.00
6_V 15_A 1.563 1.00
20_K 29_L 1.461 0.99
29_L 32_V 1.4 0.99
45_R 49_K 1.394 0.99
22_S 25_K 1.377 0.99
59_K 62_R 1.358 0.99
46_K 51_S 1.345 0.99
16_L 22_S 1.29 0.98
31_E 34_R 1.287 0.98
12_F 46_K 1.28 0.98
61_A 65_A 1.278 0.98
23_C 28_V 1.257 0.98
17_R 55_R 1.188 0.96
26_A 33_R 1.181 0.96
15_A 52_A 1.179 0.96
14_V 17_R 1.174 0.96
47_R 50_A 1.153 0.96
8_E 20_K 1.147 0.95
50_A 55_R 1.143 0.95
33_R 36_E 1.122 0.95
1_M 15_A 1.112 0.94
52_A 55_R 1.109 0.94
2_P 54_K 1.099 0.94
50_A 53_V 1.093 0.94
34_R 48_A 1.068 0.93
26_A 30_A 1.045 0.91
14_V 24_E 1.041 0.91
39_E 44_E 1.02 0.90
31_E 43_T 1.004 0.89
21_R 41_P 1.003 0.89
27_G 41_P 1.002 0.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kiyU1199.80.113Contact Map0.064
3bbnU1199.80.168Contact Map0.1
2qpvA20.36627.10.895Contact Map0.254
3s5mA10.40856.80.896Contact Map0.114
1w3iA40.43665.10.901Contact Map0.504
1ob8A20.42254.10.906Contact Map0.235
3v4gA10.38034.10.906Contact Map0.318
2ghaA20.49340.906Contact Map0.313
2z8uA40.40853.70.908Contact Map0.468
3k5iA40.43663.50.909Contact Map0.25

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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